High Sugar Diet for NASH Mice Model

June 08, 2022

BlueskyReddit
UC Davis
Molecular Biology
Graduate Student

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Company:

Research Diets

Product Name:

Rodent Diet With 40 kcal% Fat (Mostly Palm Oil), 20 kcal% Fructose and 2% Cholesterol

Catalog Number:

D09100310

We are interested in studying the potential functions of a novel class of small peptides. Preliminary data suggest certain peptides may inhibit lipid synthesis in the liver. Therefore we use this high sugar diet to induce fatty liver in mice and test if these peptides might prevent lipid accumulation. This diet feeding in two weeks can cause profound lipid accumulation in mice.

Experimental Design and Results Summary

Application

High sugar diet to rapidly cause lipid accumulation in the liver of mice.

Starting Material

N/A

Tips

This diet tends to sticky together. Needs to monitor the accessibility of mice to the diet every day.

Results Summary

We are interested in studying the potential functions of a novel class of small peptides. Preliminary data suggest certain peptides may inhibit lipid synthesis in the liver. Therefore we use this high sugar diet to induce fatty liver in mice and test if these peptides might prevent lipid accumulation. This diet feeding in two weeks can cause profound lipid accumulation in mice.

DOI or PMID #

N/A

Image Gallery

Summary

The Good

Consistent quality.

The Bad

Sticky.

The Bottom Line

We are interested in studying the potential functions of a novel class of small peptides. Preliminary data suggest certain peptides may inhibit lipid synthesis in the liver. Therefore we use this high sugar diet to induce fatty liver in mice and test if these peptides might prevent lipid accumulation. This diet feeding in two weeks can cause profound lipid accumulation in mice.

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