PanCK for Thymic Epithelial Cells

Our laboratory studies T Cell Acute Lymphoblastic Leukemia (T-ALL), a cancer of developing T cells. In order to examine the composition and organization of the tumor microenvironment, our lab utilizes a wide variety of markers to identify specific cellular subsets of the tumor microenvironment. We picked this antibody for immunofluorescence imaging knowing that it would characterize the architecture of the tumor microenvironment in T-ALL in our mouse model. PanCK will stain for cortical thymic epithelial cells (cTECs). I used it to examine thymic epithelial cell architecture on fresh, frozen tissue with IF imaging.