DNA sequencing is any process used to map out the sequence of the nucleotides that comprise a strand of DNA. Sequencing is used by researchers in molecular biology or genetics laboratories as well as clinically to make medical treatment decisions and aid in genetic counseling. Manual DNA sequencing was described in 1977 by Maxim and Gilbert’s radiolabelling method, and further refined by Sanger’s chain termination method. The Sanger method, in mass production form, is the technology which produced the first human genome in 2001, ushering in the age of genomics. SInce then, drastic new approaches and automation have been successful in making DNA sequencing faster, easier and more cost effective. However, manual DNA sequencing techniques continue to be used by smaller scale laboratories.
No single method is ideal for every application, but each has benefits.
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Decision driven by one of three general end uses.
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The MilliSentials™ Lab Labeling System provides a complete laboratory labeling solution with laboratory grade labels, a compact WIFI capable printer, and custom-designed laboratory labeling software. Features:
Laboratory grade labels
Labels can ...
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The Sapphire FL Biomolecular Imager is a field-upgradable laser scanner, with a wide selection of user-adjustable lasers and filters. It features 5-micron resolution, adjustable Z-plane focus and a wide field of view of 25cm X 25cm. Applications ...
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In the modern molecular world almost every biology lab today finds itself working with plasmid DNA in some capacity. One of the simplest tasks required is purifying plasmid DNA from small...
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The Sequi-Gen® GT is a vertical slab gel electrophoresis unit used for high resolution nucleic acid gel electrophoresis, which is crucial in experiments like DNase foot-printing, DNA finger-printing, RNase protection assay...
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