Pharmaceuticals have been detected in bodies of water globally for years, and various studies have shown that their presence impacts wildlife and ecosystems. A new study looked specifically at the impact of Escitalopram (Lexapro), a selective serotonin reuptake inhibitor (SSRI) that is used to treat depression and anxiety, on male and female zebrafish.
According to the paper published yesterday in Environmental Toxicity and Chemistry, escitalopram—at concentrations similar to those measured in the environment—can inhibit zebrafish foraging and eating behavior.
Using a video tracking system, the team from Aarhus University found a more pronounced effect of escitalopram in males than females, with male total feeding duration significantly reduced (by 73%) at the highest concentration of escitalopram.
"It is disturbing that psychoactive drugs affect vital life processes in aquatic wildlife," said corresponding author Erik Baatrup, Ph.D.
Image: Medication in the environment affects feeding behavior of fish. Image courtesy of Erik Baatrup.