Immune Checkpoint Inhibitors

Immune Checkpoint Inhibitors

Cancer cells often evade an immune system attack by co-opting immune checkpoint proteins like PD1 and PD-L1. The details behind how immune checkpoint inhibitors are being developed to expose and correct this covert process are covered here.

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Combination Therapy in Cancer Treatment
PD-1/PD-L1 blockade-based combination therapies have shown potent antitumor effects but primary ...
Biomarkers for Immune Checkpoint Inhibitor Therapy
New efforts seek to improve the efficacy of ICIs
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CAR T-cell Therapy: A New Era in Cancer Treatment
Download this white paper for more information on CAR T-cell therapy.
Spatial Profiling of the Tumor Microenvironment
A glimpse at how this tech is helping provide new insights into TME.
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Cytokine and Anticytokine Therapies for Cancer Treatment
In these studies, recombinant cytokines of high purity and activity are indispensable for various ...
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Cytokine Application in Cancer Immunotherapy
Recombinant cytokines have a great potential for cancer immunotherapy.
Immune Checkpoint Inhibitor Combination Therapy
Exploiting the best of two worlds
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Research Tools for Anti-Cancer Drug Targets
Immunotherapy harnesses the ability of the immune system to fight cancer.
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Tools for TIGIT Research
TIGIT is an emerging checkpoint inhibitor and blocking CD155:TIGIT interaction represents an ...
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Antibody Discovery Platforms to Support Functional Monoclonal Antibody ...
This webinar explores antibody discovery platforms and discusses how single b-cell sorting can be ...
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Promising Targets for Cancer Immunotherapy
This eBook investigate some of the most exciting research topics in this area, including targeting ...
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Immune Checkpoints and Drug Discovery
Biochemical assays are complemented by quantitative cell-based reporter assays which provide ...
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Tools for Immune Checkpoint Therapeutic Antibodies ResearchThis application note...
This application note summarizes recent tools developed for immune checkpoint therapeutic antibodies...
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Generation of Functional Monoclonal Antibodies by Single B Cell Cloning
Study looks at the reactivity profiles and biophysical characteristics of monoclonal antibodies ...
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Reagents for Drug Target Research
Drug target research is crucial in mechanism-based drug discovery and development.
Predicting the Response to Checkpoint Inhibitors
Despite some successes, CPIs are not magic bullets.
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Recombinant Protein Expression, Challenges and Solutions
High-quality recombinant proteins are important starting materials for successful research efforts ...
Infographic: Checkpoint Inhibitors: Centuries in the Making
Find out who coined the term vaccination and what Coley’s toxins were.
The Tumor Microenvironment and Immune Checkpoint Inhibition
Turning foe into friend.
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Reagents for Oncology Research
Oncology research encompasses many processes that have a role in cancer development and progression....
Checkpoint Protein Analysis and Characterization
Frontiers in CPI analysis involve optimizing today's analytic paradigm.
Unleashing Immunity Against Cancer
Engineering an immune system–driven attack on cancer is getting easier.
Unleashing Immunity Against Cancer
Engineering an immune system–driven attack on cancer is getting easier.
Flow Cytometry in Immuno-oncology Research
New developments are extending the utility of flow.

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