Cytokine and Anticytokine Therapies for Cancer Treatment
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Cytokine and Anticytokine Therapies for Cancer Treatment

Cytokine and Anticytokine therapies

Depending on the antitumor or protumor effects of various cytokines, two opposing cytokine-based immunotherapy strategies are used for cancer treatment: (1) cytokine therapy, in which recombinant cytokines or cytokine derivatives with antitumor effects are used directly to fight cancer cells, and (2) anticytokine therapy, in which the antagonists of cytokines or cytokine receptors are harnessed to inhibit the protumor effects of cytokines. In these studies, recombinant cytokines of high purity and activity are indispensable for various functional assays, such as cytotoxicity assay and control experiment of the cytokine drug candidates.

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