Bispecific antibodies are a focal point in antibody drug development. However, conventional monoclonal antibodies may encounter challenges with light and heavy chain mismatch when used in bispecific antibodies. KYinno has developed CLC mice, featuring a fixed light chain sequence. This innovative approach circumvents light and heavy chain mismatch issues right from the beginning. Additionally, the CLC mouse’s light chain boasts high solubility and stability. Its CDR region exhibits low immunogenicity and is easily humanized. This combination of features positions CLC mice as an ideal animal model for the development of bispecific antibodies. Download this white paper to learn more.
Please check the highlighted fields and try again.
Please enter your first and last name.
Please enter the name of the company or institution you work at.
Please enter your mailing address.
Please enter the e-mail address you would like to be contacted at.