IL-6R alpha ELISA DY227 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemIL-6R alpha ELISA
CompanyR&D Systems, a Bio-Techne Brand
Price $890.00Supplier Page View Company Product Page
Catalog NumberDY227
Quantity1 Kit (for 15 Plates)
ApplicationsELISA
Detection Range15.60 - 1000 pg/mL
ReactivityHuman
Detection TargetIL-6R alpha
StorageStore the unopened product at 2 - 8 °C. Do not use past expiration date
NCBI Full Gene Nameinterleukin 6 receptor
NCBI Gene AliasesCD126, HIES5, IL-1Ra, IL-6R, IL-6R-1, IL-6RA, IL6Q, IL6QTL, IL6RA, IL6RQ, gp80

Specifications/Features

Available conjugates: Sizes Available: 1 Kit (for 15 Plates)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Post‐exercise hot or cold water immersion does not alter perception of effort or neuroendocrine responses during subsequent moderate‐intensity exerciseExperimental PhysiologySeptember 1, 2024Campbell Menzies, Neil D. Clarke, Christopher J. A. Pugh, Charles J. Steward, C. Douglas Thake, Tom Culleninterleukin‐6 (IL‐6) (D6050, Bio‐Techne, Minneapolis, MN, USA), the soluble IL‐6 receptor (sIL‐6r) (DY227, Bio‐Techne), adrenaline (KA3768, Abnova), noradrenaline (KA3768, Abnova, Taipei City, Taipai, Taiwan)

(2) Post‐exercise hot or cold water immersion does not alter perception of effort or neuroendocrine responses during subsequent moderate‐intensity exerciseExp PhysiolJuly 6, 2024Campbell Menzies, Neil D. Clarke, Christopher J. A. Pugh, Charles J. Steward, C. Douglas Thake, Tom Culleninterleukin‐6 (IL‐6) (D6050, Bio‐Techne, Minneapolis, MN, USA), the soluble IL‐6 receptor (sIL‐6r) (DY227, Bio‐Techne), adrenaline (KA3768, Abnova), noradrenaline (KA3768, Abnova, Taipei City, Taipai, Taiwan)

(3) The Role of Pretreatment Serum Interleukin 6 in Predicting Short-Term Mortality in Patients with Advanced Pancreatic CancerBiomedicinesApril 18, 2024Se Jun Park, Ju Yeon Park, Kabsoo Shin, Tae Ho Hong, Younghoon Kim, In-Ho Kim, MyungAh Leereceptor α (sIL-6Rα) protein were measured employing DuoSet ELISA kits for each respective protein (#DY227, R&D Systems, Minneapolis, MN, USA), adhering to the provided instructions. 2.3. Defining a Cohort

(4) Associations between serum estradiol and IL-6/sIL-6R/sgp130 complex in female patients with major depressive disorderBMC PsychiatryOctober 12, 2023Ting Sun, Qian Chen, Junchi Mei, Yan Lisgp130, and sIL-6Rα were detected by enzyme-linked immunosorbent assay (ELISA) kits (Quantikine DY206, DY227, DY008, and DY228; R&D Systems, USA). The serum levels of IL-6 were measured without diluting the sample,

(5) Characterization of HZ0412a, a novel potent humanized anti-IL-6 receptor antibody that blocks IL-6R binding to gp130Antibody TherapeuticsMay 11, 2023Jianzhong Han, Xiaolei Liu, Yue Xu, Qian Wang, Li Li, Kehe Du, Chenchen Li, Hongjun Liu, Yu Chen, Jian Huangassay Antigen-binding by anti-IL-6R antibodies was measured by using an ELISA kit from R&D Systems (Cat# DY227). Briefly, 96-well plates were coated with sIL-6R-mFc fusion protein (100 μg/ml, 100 μl per well) in

(6) SARS-CoV-2 infection results in immune responses in the respiratory tract and peripheral blood that suggest mechanisms of disease severityNature communicationsMay 19, 2022Zhang W, Chua BY, Selva KJ, Kedzierski L, Ashhurst TM, Haycroft ER, Shoffner-Beck SK, Hensen L, Boyd DF, James F, et al.

(7) Reduced Expression of PD-1 in Circulating CD4+ and CD8+ Tregs Is an Early Feature of RRMSInternational journal of molecular sciencesMarch 16, 2022Machcińska M, Kierasińska M, Michniowska M, Maruszewska-Cheruiyot M, Szewczak L, Rola R, Karlińska A, Stear M, Donskow-Łysoniewska K.

(8) Tumor necrosis factor is a necroptosis-associated alarminFrontiers in immunologyJanuary 1, 2022Pinci F, Gaidt MM, Jung C, Nagl D, Kuut G, Hornung V.(BD Biosciences, Cat#550926), mmTNF (BD Biosciences, Cat#558534) and hIL-6Rα ELISA (R&D Systems, Cat#DY227) were performed according to provider’s protocol. LDH Pierce LDH Cytotoxicity Assay Kit (Thermo Fisher Scientific

(9) Discovery and characterization of a monoclonal antibody targeting a conformational epitope of IL-6/IL-6Rα to inhibit IL-6/ IL-6Rα/gp130 hexameric signaling complex formationmAbsJanuary 1, 2022Chou CC, Hua KT, Chen MW, Wu CJ, Hsu CH, Wang JT, Hsiao M, Wei LH.1 hr at room temperature. Afterward, primary anti-sIL-6Rα mouse monoclonal antibody (R&D systems, #DY227) and horseradish peroxidase (HRP)-coupled horse anti-mouse IgG secondary antibody (Cell Signaling Technology,

(10) Immune responses in COVID-19 respiratory tract and blood reveal mechanisms of disease severityResearch squareAugust 26, 2021Zhang W, Chua B, Selva K, Kedzierski L, Ashhurst T, Haycroft E, Shoffner S, Hensen L, Boyd D, James F, et al.

(11) Perturbation of the Actin Cytoskeleton in Human Hepatoma Cells Influences Interleukin-6 (IL-6) Signaling, but Not Soluble IL-6 Receptor Generation or NF-κB ActivationInternational journal of molecular sciencesJuly 2, 2021Georgieva E, Leber SL, Wex C, Garbers C.

(12) Preeclampsia Status Controls Interleukin-6 and Soluble IL-6 Receptor Release from Neutrophils and Endothelial Cells: Relevance to Increased Inflammatory ResponsesPathophysiologyApril 8, 2021Yuping Wang, Yang Gu, J. Steven Alexander, David F. Lewisby enzyme-linked immunosorbent assay (ELISA). DuoSet ELISA development kits of IL-6 (DY206), sIL-6R (DY227), and sgp130 (DY228) were purchased from R&D systems (Minneapolis, MN, USA). ELISA assay was performed

(13) Perinatal granulopoiesis and risk of pediatric asthmaeLifeFebruary 10, 2021Benjamin A Turturice, Juliana Theorell, Mary Dawn Koenig, Lisa Tussing-Humphreys, Diane R Gold, Augusto A Litonjua, Emily Oken, Sheryl L Rifas-Shiman, David L Perkins, Patricia W FinnHuman PGLYRP1/PGRP-S DuoSet ELISA R and D Systems DY2590 Commercial assay or kit Human IL6Ra DuoSet ELISA R and D Systems DY227 Commercial assay or kit RNeasy Mini Kit Qiagen 74104 Commercial assay or kit RNA 6000 Nano Kit Agilent 5067–1511 Commercial assay

(14) Interleukin-6 controls recycling and degradation, but not internalization of its receptorsThe Journal of biological chemistryJanuary 1, 2021Flynn CM, Kespohl B, Daunke T, Garbers Y, Düsterhöft S, Rose-John S, Haybaeck J, Lokau J, Aparicio-Siegmund S, Garbers C.

(15) Cathepsin S provokes interleukin-6 (IL-6) trans-signaling through cleavage of the IL-6 receptor in vitroScientific reportsDecember 10, 2020Flynn CM, Garbers Y, Düsterhöft S, Wichert R, Lokau J, Lehmann CHK, Dudziak D, Schröder B, Becker-Pauly C, Rose-John S, et al.

(16) Interleukin-6 trans-signaling is a candidate mechanism to drive progression of human DCCs during clinical latencyNature communicationsOctober 5, 2020Werner-Klein M, Grujovic A, Irlbeck C, Obradović M, Hoffmann M, Koerkel-Qu H, Lu X, Treitschke S, Köstler C, Botteron C, et al.

(17) Trans IL-6 signaling does not appear to play a role in renal scarring after urinary tract infectionJournal of pediatric urologyOctober 1, 2020Gupta S, Junquera GY, Nicassio L, Becknell B, Ching CB.

(18) Associations between the IL-6-neutralizing sIL-6R-sgp130 buffer system and coronary artery disease in postmenopausal womenAnnals of Translational MedicineMay 2, 2020Man Zhou, Wen Dai, Yan Cui, Huan Liu, Yan Lienzyme-linked immunosorbent assay (ELISA) kits that were specific for human antigens (Quantikine DY206, DY227, DY228, and DY008; R&D Systems, Minneapolis, MN, USA) (14). Serum samples were undiluted to measure

(19) Activation of Toll-like Receptor 2 (TLR2) induces Interleukin-6 trans-signalingScientific reportsMay 13, 2019Flynn CM, Garbers Y, Lokau J, Wesch D, Schulte DM, Laudes M, Lieb W, Aparicio-Siegmund S, Garbers C.detection of sIL-6R the DuoSet Human IL-6Rα ELISA kit from R&D systems (Minneapolis, MN, USA; Cat.-No. DY227) was used. Both ELISAs were performed according to the manufacturer’s instructions. For the detection

(20) Therapeutic blockade of the interleukin-6 receptor (IL-6R) allows sIL-6R generation by proteolytic cleavageCytokineFebruary 1, 2019Prenissl N, Lokau J, Rose-John S, Haybaeck J, Garbers C.

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IL-6R alpha ELISA

Human IL-6R alpha DuoSet ELISA

IL-6R alpha ELISA from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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IL-6R alpha ELISA from R&D Systems, a Bio-Techne Brand

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