Human Total Legumain DuoSet ELISA DY4769 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemHuman Total Legumain DuoSet ELISA
CompanyR&D Systems, a Bio-Techne Brand
Price $890.00Supplier Page View Company Product Page
Catalog NumberDY4769
NCBI Gene AliasesAEP, LGMN1, PRSC1
NCBI Full Gene Namelegumain
StorageStore the unopened product at 2 - 8 °C. Do not use past expiration date
Detection TargetLegumain/Asparaginyl Endopeptidase
ReactivityHuman
Detection Range31.20 - 2000 pg/mL
ApplicationsELISA
Quantity1 Kit (for 15 Plates)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Legumain is a paracrine regulator of osteoblast differentiation and mediates the inhibitory effect of TGF-β1 on osteoblast maturationFront Endocrinol (Lausanne)September 19, 2024Karl Martin Forbord, Ngoc Nguyen Lunde, Tatjana Bosnjak-Olsen, Harald Thidemann Johansen, Rigmor Solberg, Abbas Jafari(LI-COR). Legumain concentration in conditioned media was measured using a total legumain ELISA kit (DY4769; R&D Systems, RRID: AB_294369) according to the manufacturer’s protocol. 2.4 Legumain activity assay Cleavage

(2) The Cysteine Protease Legumain Is Upregulated by Vitamin D and Is a Regulator of Vitamin D Metabolism in MiceCellsDecember 22, 2023Forbord KM, Okla M, Lunde NN, Bosnjak-Olsen T, Arnekleiv G, Hesselson D, Johansen HT, Tang JCY, Kassem M, Solberg R, et al.media or mice plasma, respectively, according to the manufacturer’s protocol (R&D Systems, Catalog # DY4769, RRID: AB_294369 and MyBioSource, Catalog # MBS9718081, RRID: AB_2943631, respectively). Plasma VDBP

(3) Asparaginyl endopeptidase contributes to cetuximab resistance via MEK/ERK signaling in RAS wide-type metastatic colorectal cancerClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of MexicoMarch 1, 2023Xu X, Liu M, Peng K, Yu Y, Liu T.Biosciences). ELISA Levels of AEP protein in the cell supernatant were determined using ELISA kit (R&D Systems, DY4769) in accordance with the protocol provided by the manufacturer. Briefly, samples and standards were added

(4) Identification of the Cysteine Protease Legumain as a Potential Chronic Hypoxia-Specific Multiple Myeloma Target GeneCellsJanuary 15, 2022Clees AS, Stolp V, Häupl B, Fuhrmann DC, Wempe F, Seibert M, Weber S, Banning A, Tikkanen R, Williams R, et al.Enzyme-Linked Immunosorbent Assay (ELISA) The Human Total legumain DuoSet ELISA (R&D Systems Inc., #DY4769) was used following the manufactuers’ instructions. Supernatants of RPMI-8226, OPM-2, U266 cells cultured

(5) Legumain in Acute Coronary Syndromes: A Substudy of the PLATO (Platelet Inhibition and Patient Outcomes) TrialJournal of the American Heart AssociationSeptember 1, 2020Ida Gregersen, Annika E. Michelsen, Ngoc Nguyen Lunde, Axel Ã…kerblom, Tatevik G. Lakic, Mona Skjelland, Karolina Ryeng Skagen, Richard C. Becker, Johan LindbÃ¤ck, Anders Himmelmann, et al.analyses. Serum legumain concentrations were determined with sandwich immunoassay from R&D Systems (Duoset DY4769), Stillwater, MN. Total and differential (i.e., neutrophils, lymphocytes and monocytes) white blood cell

(6) The exosomal integrin α5β1/AEP complex derived from epithelial ovarian cancer cells promotes peritoneal metastasis through regulating mesothelial cell proliferation and migrationCellular oncology (Dordrecht)April 1, 2020Li X, Tang M, Zhu Q, Wang X, Lin Y, Wang X.detected in sera and ascites samplers by ELISA using a Human Total Legumain DuoSet ELISA kit (R&D Systems, DY4769), a Human Integrin α5 ELISA kit (R&D Systems, DY1864–05) and a Human Integrin β1 Antibody kit (R&D Systems,

(7) Mammalian legumain - A lysosomal cysteine protease with extracellular functions?BiochimieNovember 1, 2019Lunde NN, Bosnjak T, Solberg R, Johansen HT.proteins in body fluids or in vitro cell cultures. A commercially available human legumain ELISA kit (DY4769, R&D Systems) containing a legumain mAb for capture and a biotinylated legumain pAb (AF2199) for detection.

(8) Glycosylation is important for legumain localization and processing to active forms but not for cystatin E/M inhibitory functionsBiochimieAugust 1, 2017Lunde NN, Haugen MH, Bodin Larsen KB, Damgaard I, Pettersen SJ, Kasem R, Rut W, Drag M, Poreba M, Johansen HT, et al.estimation of glomerulus filtration rate [181, 182]. A commercially available human legumain ELISA-duokit (DY4769) from R&D Systems, 21 METHODOLOGICAL CONSIDERATIONS _____________________________________________________________________________ containing

(9) Asparaginyl endopeptidase improves the resistance of microtubule-targeting drugs in gastric cancer through IQGAP1 modulating the EGFR/JNK/ERK signaling pathwayOncoTargets and therapyJanuary 1, 2017Cui Y, Li Q, Li H, Wang Y, Wang H, Chen W, Zhang S, Cao J, Liu T.

(10) Development of a selected reaction monitoring mass spectrometry-based assay to detect asparaginyl endopeptidase activity in biological fluidsOncotargetOctober 25, 2016Dutta A, Potier DN, Walker MJ, Gray OJ, Parker C, Holland M, Williamson AJ, Pierce A, Unwin RD, Krishnan S, et al.

(11) Correction: Nuclear Legumain Activity in Colorectal CancerPLoS ONESeptember 19, 2013Mads H. Haugen, Harald T. Johansen, Solveig J. Pettersen, Rigmor Solberg, Klaudia Brix, Kjersti Flatmark, Gunhild M. Maelandsmocorresponding loading control (a-tubulin). ELISA measurements of human total legumain (R&D Systems, DY4769) from three separate protein isolations were performed in duplicate according to the manufacturers’

(12) Nuclear legumain activity in colorectal cancerPloS oneJanuary 1, 2013Haugen MH, Johansen HT, Pettersen SJ, Solberg R, Brix K, Flatmark K, Maelandsmo GM.corresponding loading control (α-tubulin). ELISA measurements of human total legumain (R&D Systems, DY4769) from three separate protein isolations were performed in duplicate according to the manufacturers'

(13) Integrated proteomic analysis of human cancer cells and plasma from tumor bearing mice for ovarian cancer biomarker discoveryPloS oneNovember 19, 2009Pitteri SJ, JeBailey L, Faça VM, Thorpe JD, Silva MA, Ireton RC, Horton MB, Wang H, Pruitt LC, Zhang Q, et al.

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Total Legumain/Asparaginyl Endopeptidase ELISA

Total Legumain/Asparaginyl Endopeptidase ELISA

Human Total Legumain DuoSet ELISA from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Human Total Legumain DuoSet ELISA from R&D Systems, a Bio-Techne Brand

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