Description
Product Characteristics: The AssayMax Human Protein S ELISA (Enzyme-Linked Immunosorbent Assay) kit is designed for detection of human protein S in plasma and serum. This assay employs a quantitative competitive enzyme immunoassay technique that measures human protein S in less than 3 hours. A polyclonal antibody specific for human protein S has been pre-coated onto a 96-well microplate with removable strips. Protein S in standards and samples is competed by a biotinylated protein S sandwiched by the immobilized antibody and streptavidin-peroxidase conjugate. All unbound material is then washed away and a peroxidase enzyme substrate is added. The color development is stopped and the intensity of the color is measured.
Target Information: This gene encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in this gene result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3. [provided by RefSeq, Feb 2009]