PTMScan ® Phospho-Tyrosine Rabbit mAb (P-Tyr-1000) Kit 8803S from Cell Signaling Technology

Product Specs
ItemPTMScan ® Phospho-Tyrosine Rabbit mAb (P-Tyr-1000) Kit
CompanyCell Signaling Technology
Price $2,502.00 Inquire
Catalog Number8803S
Quantity1 Kit
ApplicationsPTMScan

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Cell Signaling Technology

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Danvers, Massachusetts 01923

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Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
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Website: http://www.cellsignal.com/

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(1) Scalable phosphotyrosine enrichment with SH2 superbinder enables deep profiling of EGF responsesEMBO JJuly 3, 2026Alexis T Chang, Ricard A Rodriguez-Mias, Matthew D Berg, Sophie Moggridge, Judit Villén(CST®) sells PTMScan® antibody-conjugated magnetic beads for $2540 per 800 µL of bead slurry (Catalog #8803). Following the EasyAb-recommended use of 100 µL CST PTMScan® magnetic bead slurry per sample, the cost

(2) Regulation of cAMP levels in osteocytes by mechano-sensitive focal adhesion kinase and phosphodiesterase 8AiScienceJune 19, 2026Garyfallia Papaioannou, Tadatoshi Sato, Caroline Houghton, Chuanqing Yan, Parthena E. Kotsalidis, Katelyn E. Strauss, Thomas Dean, Courtney M. Mazur, Alissa J. Nelson, Matthew P. Stokes, et al.over C18 columns (Waters #WAT051910) and enriched using the PTMScan Phosphotyrosine pY-1000 Kit (CST #8803) as previously described.93 Samples were desalted over C18 tips prior to LC-MS/MS analysis. LC-MS/MS

(3) STING-induced blood-brain barrier opening combined with radiotherapy potentiates antitumor response in a high-grade glioma modelJ Clin InvestFebruary 16, 2026Shashwat Tripathi, Hinda Najem, Lisa Hurley, Ruochen Du, Crismita Dmello, Heba Ali, Kathleen McCortney, Karl J. Habashy, Peng Zhang, Craig M. Horbinski, et al.from Cell Signaling Technology, used at a dilution of 1:8,000. In vivo treatments. The STING agonist 8803 was administered i.c. via cannula, as per the treatment schema, at a concentration of 2.5 or 5 μg/mouse.

(4) STING-induced blood-brain barrier opening combined with radiotherapy potentiates antitumor response in a high-grade glioma modelJ Clin InvestFebruary 16, 2026Shashwat Tripathi, Hinda Najem, Lisa Hurley, Ruochen Du, Crismita Dmello, Heba Ali, Kathleen McCortney, Karl J. Habashy, Peng Zhang, Craig M. Horbinski, et al.from Cell Signaling Technology, used at a dilution of 1:8,000. In vivo treatments. The STING agonist 8803 was administered i.c. via cannula, as per the treatment schema, at a concentration of 2.5 or 5 μg/mouse.

(5) Dynamic feedback control of oncogenic tyrosine kinase signaling in acute leukemiaSci SignalFebruary 10, 2026Jaewoong Lee, Ruifeng Sun, Kohei Kume, Mark E. Robinson, Zhangliang Cheng, Kadriye Nehir Cosgun, Ning Ma, Christian Hurtz, Huimin Geng, Selina M. Luger, et al.phosphoproteomics, dried samples were resuspended and enriched with the Phosphotyrosine pY-1000 Motif Antibody (CST #8803) and were purified over C18 STAGE tips (Rappsilber). Replicate injections of each sample were run non-sequentially

(6) Alternatively spliced mini-exon B in PTPδ regulates excitatory synapses through cell-type-specific trans-synaptic PTPδ-IL1RAP interactionNat CommunMay 13, 2025Seoyeong Kim, Jae Jin Shin, Muwon Kang, Yeji Yang, Yi Sul Cho, Hyojung Paik, Jimin Kim, Yunho Yi, Suho Lee, Hei Yeun Koo, et al.#WAT051910), and enriched using the PTMScan Phospho-tyrosine pY-1000 Kit (Cell Signaling Technology, #8803). Peptides containing phospho-tyrosine were then eluted for LC-MS/MS analysis. LC-MS/MS was performed

(7) PYK2 promotes cell proliferation and epithelial-mesenchymal transition in endometriosis by phosphorylating Snail1Mol MedApril 27, 2025Lu Liu, Lan Liu, Chenjing Yue, Shiyu Du, Jiayu Liu, Zhenhai Yu(Cell Signaling Technology, #3895S, 1:2000), Phospho-Tyrosine Rabbit mAb, (Cell Signaling Technology, #8803, 1:3000). Immunofluorescent analysis The transfected cells in the logarithmic growth stage were seeded

(8) GUK1 activation is a metabolic liability in lung cancerCellMarch 6, 2025Schneider JL, Kurmi K, Dai Y, Dhiman I, Joshi S, Gassaway BM, Johnson CW, Jones N, Li Z, Joschko CP, et al.enrichment was done with phospho-tyrosine (P-Tyr-1000) immunoaffinity beads (Cell Signaling Technology Cat# 8803) and adapted from method previously described57. Briefly, approximately 2 × 108 cells were grown for

(9) CCT3/ACTN4/TFRC axis protects hepatocellular carcinoma cells from ferroptosis by inhibiting iron endocytosisJournal of Experimental & Clinical Cancer ResearchAugust 29, 2024Huihui Zhu, Qiuhong Liu, Qinna Meng, Lingjian Zhang, Siwei Ju, Jiaheng Lang, Danhua Zhu, Yongxia Chen, Nadire Aishan, Xiaoxi Ouyang, et al.(Selleck, S8037), PTMScan Phospho-Tyrosine Rabbit mAb (P-Tyr-1000) Kit (Cell Signaling Technology, 8803), PTMScan Ubiquitin Remnant Motif (K-ε-GG) Kit (Cell Signaling Technology, 5562), PTMScan Acetyl-Lysine Motif [Ac-K] Kit

(10) SHP2 as a primordial epigenetic enzyme expunges histone H3 pTyr-54 to amend androgen receptor homeostasisNature CommunicationsJuly 4, 2024Surbhi Chouhan, Dhivya Sridaran, Cody Weimholt, Jingqin Luo, Tiandao Li, Myles C. Hodgson, Luana N. Santos, Samantha Le Sommer, Bin Fang, John M. Koomen, et al.Phosphotyrosine-containing peptides (pY) were immunoprecipitated with p-Tyr-1000 beads (Cell Signaling Technology #8803 S). A nanoflow ultra-high-performance liquid chromatograph and nanoelectrospray orbitrap mass spectrometer

(11) The mitochondrial multi-omic response to exercise training across rat tissuesCell MetabolismJune 4, 2024David Amar, Nicole R. Gay, David Jimenez-Morales, Pierre M. Jean Beltran, Megan E. Ramaker, Archana Natarajan Raja, Bingqing Zhao, Yifei Sun, Shruti Marwaha, David A. Gaul, et al.endopeptidase,Wako Chemicals,NC9223464 PTMScan Phospho-Tyrosine Rabbit mAb beads,Cell Signaling Technologies,#8803 LC-MS grade water,Fisher Scientific,W64; CAS:7732–18-5 LC-MS grade 2-propanol,Fisher Scientific,A461–4;

(12) Molecular targets of glucocorticoids that elucidate their therapeutic efficacy in aggressive lymphomasCancer CellMay 13, 2024Jaewoo Choi, Michele Ceribelli, James D. Phelan, Björn Häupl, Da Wei Huang, George W. Wright, Tony Hsiao, Vivian Morris, Francesco Ciccarese, Boya Wang, et al.,Cell Signaling Technology,Cat.# 5562 PTMScan Phospho-Tyrosine Rabbit mAb Kit,Cell Signaling Technology,Cat.# 8803 Pierce BCA protein assay kit,Thermo Fisher Scientific,Cat.# 23225 Deposited data,Deposited data,Deposited

(13) Craniofacial chondrogenesis in organoids from human stem cell-derived neural crest cellsiScienceApril 19, 2024Foltz L, Avabhrath N, Lanchy JM, Levy T, Possemato A, Ariss M, Peterson B, Grimes M.sequential immunoaffinity purifications using PTM-scan kits from CST, including anti phospho-tyrosine (#8803), AKT substrate (#5561, #5563), ATM/ATR (#12267), acetyl-lysine (#13416), pan-methyl lysine (#14809),

(14) Differential network analysis of ROS1 inhibitors reveals lorlatinib polypharmacology through co-targeting PYK2Cell Chemical BiologyFebruary 15, 2024Yi Liao, Lily L. Remsing Remsing Rix, Xueli Li, Bin Fang, Victoria Izumi, Eric A. Welsh, Andrii Monastyrskyi, Eric B. Haura, John M. Koomen, Robert C. Doebele, et al.bursts, 15 seconds each, power of 15 W), purified using the Sep-Pak C18 peptide purification protocol (#8803, PTMScan Kit, Cell Signaling). Purified eluates were split into a 1.0 mg and 0.2 mg portions for pY

(15) PTEN Lipid Phosphatase Activity Suppresses Melanoma Formation by Opposing an AKT/mTOR/FRA1 Signaling AxisCancer ResearchFebruary 1, 2024Xiaonan Xu, Ilah Bok, Neel Jasani, Kaizhen Wang, Manon Chadourne, Nicol Mecozzi, Ou Deng, Eric A. Welsh, Fumi Kinose, Uwe Rix, et al.Phosphotyrosine-containing peptides were immunoprecipitated using PTMScan p-Tyr-1000 immunoaffinity beads (Cell Signaling #8803). Subsequently, samples were labeled using TMT reagents according to the manufacturer instructions (TMTpro™

(16) PTEN Lipid Phosphatase Activity Suppresses Melanoma Formation by Opposing an AKT/mTOR/FRA1 Signaling AxisCancer researchFebruary 1, 2024Xu X, Bok I, Jasani N, Wang K, Chadourne M, Mecozzi N, Deng O, Welsh EA, Kinose F, Rix U, et al.Phosphotyrosine-containing peptides were immunoprecipitated using PTMScan p-Tyr-1000 immunoaffinity beads (Cell Signaling #8803). Subsequently, samples were labeled using TMT reagents according to the manufacturer instructions (TMTpro™

(17) Development and Characterization of Selective FAK Inhibitors and PROTACs with In Vivo ActivityChemBioChemOctober 4, 2023Eriko Koide, Mikaela L. Mohardt, Zainab M. Doctor, Annan Yang, Mingfeng Hao, Katherine A. Donovan, Christina C. Kuismi, Alissa J. Nelson, Kathryn Abell, Mike Aguiar, et al.columns (Waters), and enriched using phosphotyrosine pY-1000 antibody (Cell Signaling Technology, #8803) or Fe-NTA magnetic beads (Cell Signaling Technology, #20432) as previously described[25]. 100 μg of

(18) PhosY-secretome profiling combined with kinase-substrate interaction screening defines active c-Src-driven extracellular signalingCell reportsJune 27, 2023Backe SJ, Votra SD, Stokes MP, Sebestyén E, Castelli M, Torielli L, Colombo G, Woodford MR, Mollapour M, Bourboulia D.commercial assays ,, PTMScan®PhosphoTyrosine Rabbit mAb (P-Tyr-1000) Kit,Cell Signaling Technology,Cat#8803 QIAprep Spin Miniprep Kit (250),QIAGEN,Cat#/ID: 27106 Bradford Assay,Bio-Rad,Cat#5000205 Mirus reagent

(19) Network models of protein phosphorylation, acetylation, and ubiquitination connect metabolic and cell signaling pathways in lung cancerPLOS Computational BiologyMarch 30, 2023Karen E. Ross, Guolin Zhang, Cuneyt Akcora, Yu Lin, Bin Fang, John Koomen, Eric B. Haura, Mark Grimesand purified using PTMScan Phospho-Tyrosine Rabbit mAb (P-Tyr-1000) Kit (Cell Signaling Technology #8803), PTMScan Ubiquitin Remnant Motif (K-ε-GG) Kit (Cell Signaling Technology #5562), and PTMScan Acetyl-Lysine Motif (Ac-K) Kit

(20) Integrated proteomics identifies PARP inhibitor-induced prosurvival signaling changes as potential vulnerabilities in ovarian cancerThe Journal of biological chemistryNovember 1, 2022Deng O, Dash S, Nepomuceno TC, Fang B, Yun SY, Welsh EA, Lawrence HR, Marchion D, Koomen JM, Monteiro AN, et al.using a microtip sonicator, and digested. Peptides were extracted using the Cell Signaling protocol (#8803 Cell Signaling Technology). TMT labeling, IMAC enrichment, MS analysis, and data search were performed

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PTMScan ® Phospho-Tyrosine Rabbit mAb (P-Tyr-1000) Kit

PTMScan ® Phospho-Tyrosine Rabbit mAb (P-Tyr-1000) Kit from Cell Signaling Technology

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Cell Signaling Technology

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PTMScan ® Phospho-Tyrosine Rabbit mAb (P-Tyr-1000) Kit from Cell Signaling Technology

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