FLIPR® Calcium & Calcium 3, 4, & 5 Assay Kits from Molecular Devices

Product Specs
ItemFLIPR® Calcium & Calcium 3, 4, & 5 Assay Kits
CompanyMolecular Devices
Price Supplier Page View Company Product Page
Catalog NumberFLIPR

Add to Compare List

Molecular Devices

3860 N First Street

San Jose, California 95134

United States

Phone: 408-747-1700

Company Profile

Website: www.moleculardevices.com

(1) Toxicological and pharmacodynamic evaluation of Nixodine-S [(S)-6-Methylnicotine] relative to (S)-nicotineToxicol RepAugust 15, 2026Marissa L. Smith, Sandra Costigan, J. Preston Campbell, Rick Avila, Roxana E. Weil, Willie J. McKinneyplated at 15,000–30,000 cells per well and incubated until reaching a near confluent monolayer. The FLIPR Tetra® assay was conducted according to the FLIPR membrane potential red dye kit manufacturer’s instructions

(2) Selective Brain-Penetrant TTBK1 Inhibitors Modulate TDP-43 Pathology and Rescue Cognitive Deficits in a Mouse Model of TDP-43 ProteinopathyJ Med ChemAugust 13, 2026Cecilia Sanchez-Santos, Alberto Jimenez-Amor, Loreto Martinez-Gonzalez, Vanesa Nozal, Raquel Martin-Morales, Elnaz Aledavood, Daniel Bausela, Kayla Merrigan, Karen Diaz-Palacios, Rezart Zhubi, et al.intracellular calcium are monitored using a calcium-sensitive fluorescent dye Fluo-4 (Invitrogen) in a FLIPR TETRA plate reader (Molecular Devices), with israpidine (250 nM) as a positive control. Sodium channel

(3) Activation of the angiotensin II type I receptor by a nonpeptide agonistProc Natl Acad Sci U S AAugust 11, 2026Meredith A. Skiba, Jinghan Liu, Pengxiang Shen, Jihee Kim, Elizabeth Wren, Morgan S. A. Gilman, Dean Staus, Conor McMahon, Jeffrey S. Smith, Robert J. Lefkowitz, et al.monophosphate in response to L-162,313 and AngII (IPone, CisBio). (C) G⍺q mediated calcium mobilization (FLIPR Calcium 6, Molecular Devices). (D) AT1R mediated dissociation of the Gq heterotrimer monitored via BRET

(4) TRPM8 is a non-canonical target of 7-nitrobenzodiazepinesCell Chem BiolJuly 29, 2026Logan Elkin, Evgeny G. Chulkov, Jonathan D. Enders, Anthony D. Menzel, Sang-Kyu Park, Cheryl L. Stucky, Jonathan S. Marchantsupplemented with reporter dye (10 μl) added prior to incubation (37⁰C, 40 mins). Plates were then placed in a FLIPR (Molecular Devices, serial no: FX01138), and fluorescence monitored (488nm/510–570nm) every second prior

(5) Selective GPR17 antagonism enhances structural and functional recovery in animal models of demyelinationPLoS OneJuly 27, 2026Dille De Herdt, Evy Lefevere, Véronique Brouwers, Line Hartvig, Emiel Geeraerts, Cheng-Chih Hsiao, J. Q. Alida Chen, Rui Pinto, Guillaume Duvey, Stephen Burbidge, et al.were performed by the CRO Axxam S.p.A. (Bresso, Italy) using the Fluorescence Imaging Plate Reader FLIPR TETRA ICCD camera (Molecular Devices) including the selective GPR17 agonist, MDL-29951. Additional automated liquid handling

(6) Discovery of Novel Synthetic Cyclohexene-Based Small Molecules Targeting Senescence against Age-Related Pulmonary FibrosisJ Med ChemJuly 23, 2026Iván Arribas-Álvarez, Sergio Algar, Pilar Picallos-Rabina, Anabel Sánchez-Merino, Beatriz Marcos-Ramiro, Manuel Collado, Henar Vázquez-Villa, María L. López-Rodríguez, Bellinda Benhamúpassage 18. The assay was performed as outlined in the Invitrogen information sheet and performed on the FLIPR TETRA (Molecular Devices). Powerload concentrate and water-soluble probenecid were added in the first

(7) Discovery of a peripherally restricted α2AAR agonist as a safe and broad-spectrum oral analgesicCell Rep MedJuly 21, 2026Zhiqiang Cheng, Cedric Moore, Haijiao Li, Yang Xu, Larry Zhucompound solution was added to each well. Fluorescence signals were recorded in real time using an FLIPR instrument (Tetra+ system, Molecular Devices). Activation (%) was calculated as (RFU_sample - RFU_DMSO)/(RFU_HC

(8) Gαq activation of free fatty acid receptor 4 suppresses metabolic dysfunction by disrupting Nr1h3-PPARγ axisNature CommunicationsJuly 15, 2026Yulin Kong, Jixia Wang, Zhen Wang, Shuting Yang, Xianlong Ye, Wei Wang, Hui Wang, Wanjun Deng, Yanfang Liu, Fangfang Xu, et al.were added, and the DMR signal was monitored continuously for 1 h. Fuorometric imaging plate reader (FLIPR) assay Calcium release was detected by the FLIPR Tetra instrument (Molecular Devices). Stable CHO-K1-FFAR4

(9) Probabilistic Concentration–Response Modeling and Risk Prioritization of Defined Mixtures of PFAS Using Human In Vitro AssaysEnvironmental Science & TechnologyJune 30, 2026Lucie C. Ford, Hsing-Chieh Lin, Weihsueh A. Chiu, Ivan Rusynproduction was evaluated using the Cell-Titer Glo reagent (cat. No. G2941; Promega, Madison, WI) using the FLIPR Tetra and Penta imaging device and Screenworks 4.0 Software (Molecular Devices). Some functional and

(10) NF-κB-Dependent Transcriptional Regulation of Piezo1 Mediates Bacterial Clearance on Infected Lung StiffnessAmerican Journal of Respiratory Cell and Molecular BiologyJune 25, 2026Erica M. Orsini, Adam M. Boulton, Susamma Abraham, Alyson Brown, Haley Ricci, Akash Ahuja, Bishnu Pant, Caitlin M. Snyder, Amanda Reinhardt, Amy H. Attaway, et al.(https://imagej.net/ij/). Piezo1 Ca2+ Channel Function Piezo1 Ca2+ channel function was measured using the FLIPR 5 Ca2+ assay kit (Molecular Devices, Cat. No. R8185). BMDMs were stimulated by P. aeruginosa flagellin

(11) Structural Modification and Development of N-(1,2,3,4-Tetrahydro-3-isoquinolinylmethyl)benzamide, BPR1M492, as a Potent and Rapid-Onset Opioid Analgesic with Reduced Withdrawal SymptomsJ Med ChemJune 11, 2026Po-Wei Chang, Yung-Chiao Chang, Ya-Wen Tien, Hsiao-Fu Chang, Sheng-Ren Chen, Ya-Ping Chen, Wei-Cheng Huang, Chih-Chien Hsieh, Ling Chang, Hong Zhuang, et al.medium and incubated overnight at 37 °C in a humidified atmosphere containing 5% CO2. On the assay day, FLIPR calcium assay reagent (Cat# R8141; Molecular Devices, Sunnyvale, CA, USA) was reconstituted in 1× assay

(12) Cognitive Decline, Neurologic Involvement, and Neonatal Crisis in ABCC9-Related Intellectual Disability and Myopathy SyndromeNeurol GenetJune 10, 2026Vini Nagaraj, Quentin Hugo Thomas, Paulo Ribeiro Nóbrega, Jorge Luis Rodriguez Gil, Emily Garavatti, Marcello Scala, Mariasavina Severino, Stephanie Efthymiou, Simon Amaral, Tze Chang Ng, et al.CaCl2, 1 MgCl2, 10 HEPES, 10 Glucose (pH 7.4), and incubated with 80 µL assay buffer containing 1 x FLIPR Blue Membrane Potential Dye (Molecular Devices). To activate KATP channels, certain wells included 2.5

(13) Positive allosteric modulator selective for adult muscle nicotinic acetylcholine receptorProc Natl Acad Sci U S AJune 9, 2026Richard G. Webster, Setareh Alabaf, Anna Li, Rene Beerli, Sandra Siehler, Pierre-Eloi Imbert, Leonard Lee, Judith Cossins, Magdalena Koziczak-Holbro, Ludivine Flotte, et al.buffer was prepared freshly at the day of the experiment. From the Ca2+ kinetic curves generated by the FLIPR instrument (Molecular Devices, San Jose, CA) normalized fluorescence = dF/F = [(Fmax - Fbase line)/Fbase

(14) The Selectivity Implications of Docking Libraries with Greater and Lesser Similarities to Bio-like MoleculesJournal of Medicinal ChemistryMay 28, 2026Brendan W. Hall, Kensuke Sakamoto, Xi-Ping Huang, John J. Irwin, Brian K. Shoichet, Bryan L. Rothsource plate for additions yielding a 1× final concentration (3 μM). Fluorescence was recorded on a FLIPR-Tetra (Molecular Devices): a 10 s baseline (1 read/s) was followed by 120 s postaddition acquisition

(15) Positive allosteric modulator activity of ginsenosides is restricted to P2X7 and P2X4 receptorsPurinergic SignalMay 23, 2026Elizabeth Allum, Leanne Stokesmultiple P2X receptor responses have been measured using a single assay for screening purposes. The FLIPR membrane potential assay was easy to use and has potential value in future screening programs. We used

(16) Synaptosomes isolated from cryopreserved MND motor cortex reveal altered calcium handling and reduced complex IV–linked respirationFrontiers in Synaptic NeuroscienceMay 22, 2026Sean D. Morrison, Lotten Ragnarsson, Sarah O. Cook, Joseph A. Rothnagel, Ernst Wolvetang, Bahaa Al-mhanawi, Mohammed R. Shaker, Thomas Robertson, Peter R. Dodd, Peter G. Noakes(RFU) in response to potassium chloride (KCl) was measured in a Fluorometric Imaging Plate Reader (FLIPR™; Molecular Devices) using a cooled CCD camera with excitation at 470–495 nm and emission at 515–575

(17) Discovery and Characterization of a Nonacidic Small-Molecule Inhibitor of the Sodium-Coupled Dicarboxylate Transporter NaCTJournal of Medicinal ChemistryMay 14, 2026Andrew Quigley, Jörg T. Kley, Alexander Pautsch, Stefan G. Kauschke, Amy Chu-Antypas, Annamaria Tessitore, Claire Strain-Damerell, Leela Shrestha, Dieter Wiedenmayer, Nicola A. Burgess-Brown, et al.spectrometer (Agilent Technologies Inc., Palo Alto, CA, USA). Membrane Potential Assays Using the FLIPR Membrane Potential Kit for measuring membrane potential (Molecular Devices, catalog no. R-8123), compounds

(18) Neurokinin‐1 receptor activation protects against cardiac fibrosis, inflammation and diastolic dysfunction in type 2 diabetic miceBritish Journal of PharmacologyApril 25, 2026Alexander Widiapradja, Heather Connery, Brody J. Helmick, Kallie J. Schafner, Vamsi Manchikalapudi, Hannah Horvath, Sophia Gugino, Tamas Kriska, Anja Herrnreiter, Evan DeVallance, et al.intracellular calcium [Ca2+]i mobilisation assay was performed using a fluorescence imaging plate reader (FLIPR, Molecular Devices) as previously described (Kriska et al., 2022; Park et al., 2018). In brief, human

(19) The Discovery of RGH-706, a Highly Efficacious MCH1 Receptor Antagonist, for the Treatment of Obesity and Insatiable HungerJournal of Medicinal ChemistryApril 23, 2026Gyula Beke, András Boros, György M. Keserű, Balázs Krámos, Krisztina Katalin Szalai, Anikó Gere, Mónika Vastag, Márta Thán, Balázs Varga, Ottilia Balázs, et al.of measurement, the culture medium was removed from the cells, and a fluorescent Ca2+-sensitive dye (FLIPR calcium 5 kit, Molecular Devices R8186) was added to the cells at a 4× dilution compared to the recommended

(20) Monoclonal antibody inhibition of PAR2 reduces phenotype severity and pain in murine inflammatory bowel diseasePain RepApril 20, 2026Anne Ritoux, Laura J. Grundy, Pravallika Manjappa, Luke W. Paine, Jessica Neisen, John E. Linley, Ewan St. John SmithKit (ThermoFisher, Waltham, MA). Ca2+ responses measured using the fluorescence imaging plate reader (FLIPR) Tetra system (Molecular Devices, San Jose, CA); excitation and emission wavelengths: 470 to 495 nm

Be the First to Write a Review!

Scientific Reports

Proc Natl Acad Sci U S A

FLIPR® Calcium & Calcium 3, 4, & 5 Assay Kits from Molecular Devices

Description

Molecular Devices

Citations (1067)

Reviews

FLIPR® Calcium & Calcium 3, 4, & 5 Assay Kits from Molecular Devices

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map