Description
CSF/Urine Total Protein reagent is used for the quantitative determination of total protein, using manual or automated procedure, in human urine or cerebrospinal fluid. Measurement of Urine Protein is becoming increasingly important in the detection of renal pathology. Proteinuria (increased amounts of protein in urine) can occur in increased glomerular permeability, defective tubular reabsorption and abnormal secretion of protein into the urinary tract. Albuminuria (increased amounts of albumin in urine) has been recognized as an early indicator of renal damage in diabetes, that can be reversed if detected and treated sufficiently early. The measurement of CSF total protein and specific protein is used to detect increased permeability of the blood/brain barrier (the capillary endothelium of vessels of the central nervous system) to plasma proteins or to detect increased intrathecal secretion of immunoglobins.