Description
Creatinine reagent is used for the quantitative determination of creatinine in human serum. Creatinine, an anhydride of creatine, is a waste product formed by the spontaneous dehydration of kidneys. Most of the creatinine is found in muscle tissue where it is present as creatine phosphate and serve, as a high-energy storage reservoir for conversion to ATP. Independent of diet serum creatinine concentrations depends almost entirely upon its excretion rate by the kidneys. For this reason its elevation is highly specific for kidney diseases.