Description
For the quantitative determination of alkaline phosphatase in human serum. For the quantitative determination of alkaline phosphatase in human serum. Phosphatase (ALP) levels are of interest in the diagnosis of hepatobiliary disorder and bone disease. Most of the ALP in the normal adult serum is from the liver or biliary tract. Normal alkaline phosphatase levels are age dependent, and levels are elevated during periods of active bone growth. Moderate elevations of ALP (not involving the liver or bone) may be attributed to Hodgkin's disease, congestive heart failure, and abdominal bacterial infections. Elevations also occur in the third trimester of pregnancy. Alkaline phosphatase is determined by measuring the rate of hydrolysis of various phosphate esters.