Fig 1: Expressions of the receptor for advanced glycation end products (RAGE) in the lung sections and bronchoalveolar lavage fluid (BALF) of ovalbumin (OVA)-challenged mice. Mice were treated or not with 0.5% methylglyoxal (MGO) for 12 weeks in the drinking water alone or combined with metformin (MET). Panels (A,B) show, respectively, representative images and percent quantification (% marked area) of RAGE by immunohistochemistry (IHC; brown staining) of the peribronchiolar regions (bar = 200 µm, 200× objective). Panel (C) shows the RAGE expression by RT-PCR in the lung homogenates, and panel (D) shows the levels in BALF. Data are expressed as mean ± SEM for (n = 7–8). * p < 0.05 compared with respective vehicle groups. # p< 0.05 compared with the MGO + OVA in vehicle groups.
Supplier Page from Abcam for Mouse RAGE ELISA Kit