Human GDF-15 DuoSet ELISA DY957 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemHuman GDF-15 DuoSet ELISA
CompanyR&D Systems, a Bio-Techne Brand
Price $890.00Supplier Page View Company Product Page
Catalog NumberDY957
Quantity1 Kit (for 15 Plates)
ApplicationsELISA
Detection Range7.81 - 500 pg/mL
ReactivityHuman
Detection TargetGDF-15
StorageStore the unopened product at 2 - 8 °C. Do not use past expiration date
NCBI Full Gene Namegrowth differentiation factor 15
NCBI Gene AliasesGDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Systemic Drivers and Molecular Mechanisms of Sarcopenia in Aetiology-Specific End-Stage Liver DiseaseJ Cachexia Sarcopenia MuscleApril 26, 2026Thomas Nicholson, Sophie L. Allen, Jonathan I. Quinlan, Amritpal Dhaliwal, Michael Macleod, Joshua Price, Jon Hazeldine, Michael S. Sagmeister, Caitlin Ditchfield, Kirsty C. McGee, et al.Hertfordshire, UK) (Diabetes 10‐Plex #171A7001M, Bio‐Rad, Hertfordshire, UK) or individual ELISAs (DY957, DY788; R&D Systems, MN, USA) following manufacturer protocols. All the samples were measured in duplicate. 2.5

(2) Growth Differentiation Factor 15 and Physical Function Impairment in the SardiNIA StudyJournal of Clinical MedicineMarch 29, 2026Nicia I. Profili, Edoardo Fiorillo, Valeria Orrù, Maria Benelli, Francesco Cucca, Alessandro P. Delitalasamples were drawn in the morning after overnight fasting. Serum GDF-15 levels were measured by ELISA (DY957 R&D Systems Inc., 614 McKinley Place N.E. 55413 Minneapolis, MN, USA), as previously reported [21].

(3) Functional characterization of the GWAS lead SNP rs888663 and effects of GDF15 SNPs on GDF15 levels in gestational hypertension and preeclampsiaMol Biol RepMarch 7, 2026Daniela A. Pereira, Julyane N. S. Kaihara, Luis Fernando P. Passeti, João Locke F. Araújo, Renan P. Souza, Ana C. Palei, Ricardo C. Cavalli, Chengyu Deng, Nadav Ahituv, Valeria C. Sandrim, et al.measurement Plasma GDF-15 concentrations were assessed using Human GDF-15 DuoSet ELISA kit (Catalog#DY957, R&D Systems, Minneapolis, MN, USA), following the manufacturer’s instructions. Samples were diluted

(4) GDF15 orchestrates mitochondrial-immune crosstalk via SMAD7-HIF-1α-PKM2 cascade to attenuate septic liver injuryFrontiers in ImmunologyJanuary 22, 2026Xiandong Kuang, Zhili Niu, Wenqiang Liu, Zhaoyang Huang, Shuo Li, Ye Zhang, Li Wang, Xin Cai, Faxi Wang, Pingan Zhang24 hours of diagnosis. Serum GDF15 levels were quantified using a commercial ELISA kit (R&D Systems, DY957). Clinical and laboratory data were obtained from medical records. The study was approved by the Institutional

(5) The Effect of Thyroid Function on GDF15 LevelsInternational Journal of Molecular SciencesNovember 16, 2025Nicia I. Profili, Edoardo Fiorillo, Valeria Orrù, Francesco Cucca, Alessandro P. Delitalawas immediately isolated and stored at −80 °C until use. Serum GDF-15 levels were measured by ELISA (DY957 R&D Systems). The optical density of each sample was determined using a microplate reader set to 450

(6) Effects of a two-week modified ketogenic diet on circulating lipoprotein subclasses, GDF15, and FGF21 in obese adultsJournal of Translational MedicineNovember 7, 2025Nana Zhang, Na Liu, Guoxia Zhao, Juan Yan, Pinghua Zhang, Xiaomiao Li, Jie Zhouusing ELISA assays: GDF15 was measured with Human GDF15 Quantikine ELISA Kit (R&D Systems, USA; Cat# DY957; range: 31.2–2000 pg/mL; sensitivity: <10 pg/mL), and FGF21 with Human FGF21 Quantikine ELISA Kit (Cat#

(7) GDF15 regulates development and growth of sympathetic neurons to enhance energy expenditure and thermogenesisExperimental & Molecular MedicineOctober 1, 2025Jinyoung Kim, Annie Zhao, Seo Hyun Park, Jaeseok Han, Deok-Hyeon Cheon, Sang-Hyeon Ju, Yoonhyuk Jang, Kon Chu, Hyung Jin Choi, Jiyoon Kim, et al.separated from the peripheral blood were determined using Human GDF-15 DuoSet ELISA Kit (R&D Systems, DY957) and Mouse GDF-15 DuoSet ELISA Kits (R&D Systems, DY6385), according to the manufacturer’s instructions. Statistical

(8) Dynamics of the Novel Cardiac Biomarkers sST2, H-FABP, GDF-15 and suPAR in HFrEF Patients Undergoing Heart Failure Therapy, a Pilot StudyJournal of clinical medicineAugust 11, 2025Ohnewein B, Shomanova Z, Jirak P, Paar V, Topf A, Pylypenko L, Schäbinger M, Volg F, Hoppe UC, Pistulli R, et al.analysis. 2.4. Biomarker Analysis Serum concentrations of sST2 (DY523B-05), suPAR (DY807), GDF-15 (DY957) and H-FABP (DY1678) were measured by commercially available enzyme-linked immunosorbent assays (ELISAs),

(9) Biomarkers of progressive multiple sclerosis decrease following autologous hematopoietic stem cell transplantationJ NeuroinflammationJuly 17, 2025Ida Erngren, Katarina Lundblad, Ivan Pavlovic, Asma Al-Grety, Anders Larsson, Kim Kultima, Joachim Burmanwas analyzed with a Human GDF-15 DuoSet ELISA (R&D Systems, Minneapolis, MN, United States. Cat. No. DY957) in the same laboratory by board certified technicians who were blinded to clinical data. YKL-40 was

(10) Restoration of the Tumor Suppressor Function of Y220C-Mutant p53 by Rezatapopt, a Small-Molecule ReactivatorCancer discoveryJune 3, 2025Puzio-Kuter AM, Xu L, McBrayer MK, Dominique R, Li HH, Fahr BJ, Brown AM, Wiebesiek AE, Russo BM, Mulligan CL, et al.performed according to the manufacturer’s instructions (R&D Systems, Cat. # DYC1047, DYC1244-2, and DY957). In brief, 96-well plates were coated with the respective capture antibody and incubated overnight

(11) Age‐Associated Increase in Growth Differentiation Factor 15 Levels Correlates With Central Arterial Stiffness and Predicts All‐Cause Mortality in a Sardinian Population CohortJournal of the American Heart AssociationMay 20, 2025Richard Oppong, Valeria Orru, Michele Marongiu, Yong Qian, Carlo Sidore, Alessandro Delitala, Marco Orru, Antonella Mulas, Maria Grazia Piras, Christopher H. Morrell, et al.Assays Serum fraction was aliquoted and stored at −80° until assay. GDF‐15 levels were assessed by ELISA (DY957 R&D Systems). The optical density of each sample was determined using a microplate reader set to 450

(12) Interplay between sarcopenia, GDF-15, and the efficacy of nivolumab plus ipilimumab in patients with mismatch repair deficient metastatic colorectal cancer: final survival analysis of the phase II GERCOR NIPICOL studyJ Immunother CancerMay 19, 2025Leonard Depotte, Paula Nay, Christophe Borg, Aurélia Meurisse, Julie Henriques, Jaafar Bennouna, Christelle De La Fouchardière, David Tougeron, Thibault Mazard, Benoist Chibaudel, et al.plasma freezing. GDF-15 levels were determined using the Human GDF-15 DuoSet ELISA Kit (R&D Systems, DY957), according to the manufacturer’s instructions. Each sample was analyzed in duplicate, and robustness

(13) Elevated Plasma Level of Arginine and Its Metabolites at Labor Among Women With Preeclampsia: A Prospective Cohort StudyAmerican Journal of HypertensionFebruary 18, 2025Tansim Akhter, Mikael Hedeland, Jonas Bergquist, Anders Larsson, Ove Axelsson, Susanne Hesselman, Alkistis SkalkidouLaboratories (6K26-41, Abbott Park, IL). Analyses of TNF-R1 (DY225) and TNF-R2 (DY726) and GDF-15 (DY957) were performed using commercial sandwich ELISA kits (R&D Systems, Minneapolis, MN). Ethical approval Apart

(14) Effect of rhGH treatment on lipidome and brown fat activity in prepuberal small for gestational age children: a pilot studySci RepFebruary 8, 2025Lorena González, Carolina Gonzalez-Riano, Pablo Fernández-García, Rubén Cereijo, Aina Valls, Andrea Soria-Gondek, Nativitat Real, Belén Requena, Joan Bel-Comos, Patricia Corrales, et al.protein-8b (BMP8B) (MBS944757, MyBioSource), Growth-and-differentiation factor-15 (GDF15) (Duo set ELISA DY957 Bio-Techne and Duo set ELISA ancillary reagent kit 2 DY008 Bio-Techne), Adiponectin (EZHADP-61 K, Merck

(15) The emerging role of growth differentiation factor 15 as a potential disease biomarker in juvenile dermatomyositisRheumatology (Oxford)February 1, 2025Bhargavi Duvvuri, Jorge A Gonzalez-Chapa, Lauren M Pachman, Gabrielle A Morgan, Nidhi Naik, Susan Shenoi, Christian LoodHuman GDF-15 DuoSet ELISA GDF-15 levels in plasma (dilution 1:10) were measured using the human GDF-15 DuoSet ELISA (DY957, R&D Systems) following the manufacturer’s instructions. Statistical analyses Statistical analyses

(16) Neutralizing GDF-15 can overcome anti-PD-1 and anti-PD-L1 resistance in solid tumoursNatureJanuary 1, 2025Melero I, de Miguel Luken M, de Velasco G, Garralda E, Martín-Liberal J, Joerger M, Alonso G, Goebeler ME, Schuler M, König D, et al.according to the manufacturer’s instructions (R&D Systems; human GDF-15 DuoSet ELISA Kit, catalogue no. DY957). Total GDF-15 levels (free GDF-15 plus visugromab-GDF-15 complex) during treatment were determined

(17) Growth Differentiation Factor 15 as a Marker for Chronic Ventricular PacingJournal of clinical medicineDecember 18, 2024Edlinger C, Bannehr M, Lichtenauer M, Paar V, Jankowska P, Hauptmann L, Hoppe UC, Butter C, Schernthaner C.

(18) GDF15 and LCN2 for early detection and prognosis of pancreatic cancerTranslational OncologyDecember 1, 2024Xinxia Zhu, Brennan Olson, Dove Keith, Mason A Norgard, Peter R Levasseur, Parham Diba, Sara Protzek, Ju Li, Xiaolin Li, Tetiana Korzun, et al.enzyme-linked immunosorbent assay (ELISA) kits following the manufacturers’ instructions (R&D Systems, catalog # DY957, DY1757-05, DY206-05, DY6385-05, DY1857-05, DY406-05). Human CA19-9 in patient serum was also measured

(19) Daily GDF15 treatment has sex‐specific effects on body weight and food intake and does not enhance the effects of voluntary physical activity in miceThe Journal of PhysiologyDecember 1, 2024Stewart Jeromson, Michael Akcan, Bradley Baranowski, Meagan Arbeau, Annalaura Bellucci, David C. Wrightstored at –80°C until further analysis. Circulating hormones and metabolites Human (catalog. no. DY957; R&D Systems, Minneapolis, MN, USA) and mouse (catalog. no. DY6385; R&D Systems) serum GDF15 concentrations

(20) Novel Biomarkers as Potential Predictors of Decompensated Advanced Chronic Heart Failure-Single Center StudyJournal of clinical medicineNovember 14, 2024Fröhling T, Semo D, Mirna M, Paar V, Shomanova Z, Motloch LJ, Rukosujew A, Sindermann JR, Lichtenauer M, Pistulli R.biomarkers were measured with commercially available ELISA kits (DuoSet ELISA DY1678, DY523B, DY807, DY957 and DFTA00, R&D Systems, Minneapolis, MN, USA) according to the manufacturer’s instructions. In addition,

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GDF-15 ELISA

Human GDF-15 DuoSet ELISA

Human GDF-15 DuoSet ELISA from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Human GDF-15 DuoSet ELISA from R&D Systems, a Bio-Techne Brand

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