Fig 1: ROC characteristics for prediction of AKI in post-cardiac surgery patients (a) by the AKI peptide marker panel and (b) by the single markers NGAL and KIM-1. Whereas for the AKI peptide marker panel the sensitivity and specificity was determined at the previously established cut-off, these values were determined for NGAL and KIM-1 at the optimal cut-off according to the Youden index. AKI acute kidney injury, AUC area under the ROC curve, KIM-1 kidney injury molecule-1, NGAL neutrophil gelatinase-associated lipocalin, ROC receiver operating characteristic
Fig 2: Distribution of classification scores of the AKI marker pattern (upper panel) and NGAL levels in ng/mL (lower panel) in AKI and non-AKI patient subgroups showing either progression or lack of nonocclusive mesenteric ischemia (NOMI) or death. A post hoc test was performed for average rank differences between the different subgroups (each with p < 0.05) after a significant result in the global Kruskal-Wallis test (p < 0.0001). AKI acute kidney injury, NGAL neutrophil gelatinase-associated lipocalin
Fig 3: Classification accuracy of the AKI peptide marker pattern and the other AKI predictive markers NGAL, KIM-1 and EuroSCORE II for the AKI-associated endpoints nonocclusive mesenteric ischemia (NOMI) and death in comparative ROC analysis. Shown is a receiver operating curve (ROC) comparison of the different prognostic markers for the endpoints NOMI (upper left panel) and death (upper right panel) and a table summarizing the corresponding ROC-derived area under the curve (AUC) values of the different prognostic markers for these two AKI-associated endpoints. AKI acute kidney injury, KIM-1 kidney injury molecule-1, NGAL neutrophil gelatinase-associated lipocalin
Supplier Page from Enzo Life Sciences, Inc. for NGAL (human) ELISA kit