Description
ScienCell's GeneQuery™ Human Pericyte Biology qPCR Array Kit (GQH-PER) profiles 88 key genes involved in pericyte function during angiogenesis and in immunity. In vasculature, pericytes function as mural cells on small blood vessels and they help maintain the blood-brain barrier (BBB), an integral homeostatic brain function. Pericytes also possess macrophage-like properties when functioning in the immune response. Defects in pericyte function can result in BBB breakdown and aberrant vasculature formation. GeneQuery™ qPCR array kits are qPCR ready in a 96-well plate format, with each well containing one primer set that recognizes and efficiently amplifies a specific target gene's cDNA. The carefully designed primers ensure that: (i) the optimal annealing temperature in qPCR analysis is 65°C (with 2 mM Mg2+and no DMSO); (ii) the primer set recognizes all known transcript variants of the target gene, unless otherwise noted; and (iii) only one gene is amplified. Each primer set has been validated by qPCR with melt curve analysis and gel electrophoresis