Bcl-2 Antibody PA1-30411 from Thermo Fisher Scientific

Product Specs
ItemBcl-2 Antibody
CompanyThermo Fisher Scientific
Price Supplier Page
Catalog NumberPA1-30411
NCBI Gene AliasesC430015F12Rik, PPP1R50, Bcl-2, D630044D05Rik, D830018M01Rik
Conjugate/TagUnconjugated
IsotypeIgG
HostRabbit
ApplicationsImmunohistochemistry (Frozen), Immunoprecipitation, Western Blot
ClonalityPolyclonal
Quantity1 mL
FormatPBS with 0.2% gelatin and 0.1% sodium azide
ReactivityHuman, Mouse, Rat
TargetBcl-2
NCBI Full Gene NameBCL2 apoptosis regulator, B cell leukemia/lymphoma 2, BCL2, apoptosis regulator
Concentration0.2 mg/mL
ImmunogenPeptide mapping to the amino terminus of Human Bcl-2
Storage Temperature4° C, do not freeze
PurityAffinity chromatography
Antibody TypePrimary
Storage4°C, do not freeze

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Thermo Fisher Scientific

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Waltham, MA 02451

United States

Phone: 800-678-5599
Fax: 800-331-2286

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Website: www.thermofisher.com

(1) Doxepin as OCT2 inhibitor ameliorates inflammatory response and modulates PI3K/Akt signaling associated with cisplatin-induced nephrotoxicity in ratsNaunyn-Schmiedeberg's archives of pharmacologyApril 1, 2025Fawzy MH, Moustafa YM, Khodeer DM, Saeed NM, El-Sayed NM.incubated overnight at 4 °C with BAX (Cat. No. MA5-14003, Thermo Fisher Scientific), Bcl-2 (Cat. No. PA1-30411, Thermo Fisher Scientific), and anti-Caspase 3 (Cat. No. RB-1197-R7, Thermo Fisher Scientific) primary

(2) Supplementation with Standardized Green/Black or White Tea Extracts Attenuates Hypertension and Ischemia-Reperfusion-Induced Myocardial Damage in Mice Infused with Angiotensin IIAntioxidants (Basel)January 3, 2025Mario de la Fuente-Muñoz, Marta Román-Carmena, Sara Amor, María C. Iglesias-de la Cruz, Patricia Martorell, Sonia Guilera-Bermell, Reme García Bou, Antonio M. Inarejos-García, Ángel L. García-Villalón, Miriam Granadoantibodies for Caspase 8 (1:2000; #PA5-20118; Thermo Scientific, Waltham, MA, USA) or Bcl-2 (1:1000; #PA1-30411; Thermo Scientific, Waltham, MA, USA) at 4 °C overnight. Next, membranes were washed with TBS-T and

(3) Enhanced upregulation of SIRT1 via pioglitazone and ligustrazine confers protection against ethanol-induced gastric ulcer in ratsNaunyn-Schmiedeberg's archives of pharmacologyAugust 1, 2024Mahmoud SA, Elkhoely A, El-Sayed EK, Ahmed AAE.antibody (Thermo Fisher, Catalog # MA5 -14003, USA) (1:100) and anti-Bcl2 (Thermo Fisher, Catalog # PA1-30411, USA) (1:100) for overnight at 4°C. Afterward, sections were washed out with PBS and incubated with

(4) Targeting Autophagy, Apoptosis, and Oxidative Perturbations with Dapagliflozin Mitigates Cadmium-Induced Cognitive Dysfunction in RatsBiomedicinesNovember 8, 2023Arab HH, Eid AH, Alsufyani SE, Ashour AM, El-Sheikh AAK, Darwish HW, Sabry FM.at 4 degrees Celsius with either anti-Bax (Cat. # 33-6600; dilution of 1:100) or anti-Bcl-2 (Cat. # PA1-30411; dilution of 1:100, Thermo Fisher Scientific, Rockford, IL, USA). The tissue sections were washed with

(5) Targeting Autophagy, Apoptosis, and SIRT1/Nrf2 Axis with Topiramate Underlies Its Neuroprotective Effect against Cadmium-Evoked Cognitive Deficits in RatsPharmaceuticals (Basel, Switzerland)August 29, 2023Arab HH, Eid AH, Yahia R, Alsufyani SE, Ashour AM, El-Sheikh AAK, Darwish HW, Saad MA, Al-Shorbagy MY, Masoud MA.Cat. # 33-6600; Thermo Fisher Scientific, Fremont, CA, USA), or anti-Bcl-2 (1:100 dilution; Cat. # PA1-30411). The tissue slices were rinsed in PBS and treated for 20 min with an HRP-labeled secondary antibody

(6) Neuroprotective Impact of Linagliptin against Cadmium-Induced Cognitive Impairment and Neuropathological Aberrations: Targeting SIRT1/Nrf2 Axis, Apoptosis, and AutophagyPharmaceuticals (Basel, Switzerland)July 27, 2023Arab HH, Eid AH, Alsufyani SE, Ashour AM, El-Sheikh AAK, Darwish HW, Georgy GS.then, overnight application of the primary antibodies was performed in the fridge: anti-Bcl-2 (Cat. # PA1-30411; 1:100 dilution) or anti-Bax (Thermo Fisher Scientific, Waltham, MA, USA; Cat. # 33-6600; 1:100 dilution).

(7) Stimulation of Autophagy by Dapagliflozin Mitigates Cadmium-Induced Testicular Dysfunction in Rats: The Role of AMPK/mTOR and SIRT1/Nrf2/HO-1 PathwaysPharmaceuticals (Basel, Switzerland)July 14, 2023Arab HH, Fikry EM, Alsufyani SE, Ashour AM, El-Sheikh AAK, Darwish HW, Al-Hossaini AM, Saad MA, Al-Shorbagy MY, Eid AH.primary antibodies: anti-Bcl-2 (Thermo Fisher Scientific, Waltham, MA, USA, 1:100 dilution; Cat. no. PA1-30411), or anti-Bax (Thermo Fisher Scientific, Waltham, MA, USA, 1:100 dilution, Cat. no. MA5-14003). The

(8) Calotropis gigantea stem bark extract activates HepG2 cell apoptosis through ROS and its effect on cytochrome P450HeliyonMay 1, 2023Suknoppakit P, Wangteeraprasert A, Simanurak O, Somran J, Parhira S, Pekthong D, Srisawang P.incubated overnight at 4 °C with primary antibodies, including rabbit polyclonal β-cell lymphoma 2 (Bcl-2) (PA1-30411, Thermo Fisher Scientific, USA), rabbit polyclonal SOD2/MnSOD (AF5144, Affinity bioscience, USA), rabbit

(9) Topiramate Reprofiling for the Attenuation of Cadmium-Induced Testicular Impairment in Rats: Role of NLRP3 Inflammasome and AMPK/mTOR-Linked AutophagyPharmaceuticals (Basel, Switzerland)November 14, 2022Arab HH, Abd El Aal HA, Alsufyani SE, El-Sheikh AAK, Arafa EA, Ashour AM, Kabel AM, Eid AH.Anti-NLRP3 (Catalog # GTX00763, GeneTex Inc., Irvine, CA, USA, 1:100 dilution), anti-Bcl-2 (Catalog # PA1-30411, 1:100 dilution, Thermo Fisher Scientific, Waltham, MA, USA) or anti-Bax (Cat. # MA5-14003, 1:100 dilution,

(10) Repositioning Linagliptin for the Mitigation of Cadmium-Induced Testicular Dysfunction in Rats: Targeting HMGB1/TLR4/NLRP3 Axis and AutophagyPharmaceuticals (Basel, Switzerland)July 11, 2022Arab HH, Elhemiely AA, El-Sheikh AAK, Khabbaz HJA, Arafa EA, Ashour AM, Kabel AM, Eid AH.dilution; Catalog # GTX00763, GeneTex Inc., Irvine, CA, USA), anti-Bcl-2 (1:100 dilution; Catalog # PA1-30411), or anti-Bax (1:100 dilution; Catalog # 33-6600; Thermo Fisher Scientific, Waltham, MA, USA). After

(11) Hesperidin and eugenol attenuate cadmium-induced nephrotoxicity via regulation of oxidative stress, Bax/Bcl2 and cleaved caspase 3 expressionTurkish Journal of BiochemistryDecember 23, 2020Rasha Hussein, Marwa Khalaf, Wafaa Mohamedmonoclonal antibody (Cat #: MA5 -14003, Thermo Fisher Scientiﬁc, USA) and Bcl2 polyclonal antibody (Cat #: PA1-30411, Thermo Fisher Scientiﬁc, USA) separately Results The effect of Hesp and Eug on Cd-induced functional

(12) Diallyl sulfide ameliorates carbon tetrachloride-induced hepatotoxicity in rats via suppressing stress-activated MAPK signaling pathwaysJournal of biochemical and molecular toxicologyJune 1, 2019Elkhoely A.

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Bcl-2 Antibody

Bcl-2 Antibody from Thermo Fisher Scientific

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Bcl-2 Antibody from Thermo Fisher Scientific

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