Anti-HMGB1 antibody GTX101277 from GeneTex

Product Specs
ItemAnti-HMGB1 antibody
CompanyGeneTex
Price $169.00Supplier Page
Catalog NumberGTX101277
Quantity25 µl
FormatPBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300
ApplicationsWB, ICC/IF, IHC-P, IHC-Wm, IHC, IHC (Free Floating)
Conjugate/TagUnconjugated
Concentration0.43mg/ml
ReactivityHuman, Mouse, Rat, Zebrafish, Pig
HostRabbit
IsotypeIgG
PurityPurified by antigen-affinity chromatography
TargetHMGB1
Molecular Weight25
ClonalityPolyclonal
ImmunogenRecombinant protein encompassing a sequence within the center region of human HMGB1. The exact sequence is proprietary
Antibody TypePrimary Antibodies
NCBI Full Gene Namehigh mobility group box 1
NCBI Gene Aliaseshigh mobility group box 1, HMG-1, HMG1, HMG3, SBP-1, HMG-1, HMG1, SBP-1, HMG3
Research AreaEpigenetics
Gene NameHMGB1

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GeneTex

GeneTex, Inc. 2456 Alton Parkway

Irvine, California 92606

United States

Phone: 1-877-GeneTex (436-3839) or 949-553-1900
Fax: 949-309-2888

Company Profile

Website: http://www.genetex.com

(1) Aclacinomycin enhances the killing effect of allogeneic NK cells on acute myeloid leukemia cells by inducing immunogenic cell deathFrontiers in immunologyJanuary 1, 2025Ye Y, Liu N, Zeng Y, Guo Z, Wang X, Xu X.

(2) Knockdown of HMGB1 inhibits the crosstalk between oral squamous cell carcinoma cells and tumor-associated macrophagesInternational immunopharmacologyJune 1, 2023Wen J, Yin P, Su Y, Gao F, Wu Y, Zhang W, Chi P, Chen J, Zhang X.

(3) ATR prevents Ca²⁺ overload-induced necrotic cell death through phosphorylation-mediated inactivation of PARP1 without DNA damage signalingFASEB journal : official publication of the Federation of American Societies for Experimental BiologyMay 1, 2021Li Z, Wang-Heaton H, Cartwright BM, Makinwa Y, Hilton BA, Musich PR, Shkriabai N, Kvaratskhelia M, Guan S, Chen Q, et al.from Bethyl Laboratories. The phospho‐ATR antibody (T1989; cat# GTX128145) and HMGB1 antibody (cat# GTX101277) were from GeneTex. Antibody against poly (ADP‐ribose) (PAR) (Cat#4338‐MC‐50) was from Trevigin. 2.2

(4) N-(2'-Hydroxyphenyl)-2-Propylpentanamide (HO-AAVPA) Inhibits HDAC1 and Increases the Translocation of HMGB1 Levels in Human Cervical Cancer CellsInternational journal of molecular sciencesAugust 16, 2020Sixto-López Y, Rosales-Hernández MC, Contis-Montes de Oca A, Fragoso-Morales LG, Mendieta-Wejebe JE, Correa-Basurto AM, Abarca-Rojano E, Correa-Basurto J.Tween-Triton 0.5%) for 5 min. Subsequently, the cells were washed and the primary antibody, anti-HMGB1 (GTX101277, GeneTex, Alton Pkwy Irvine, CA, USA), was added at a ratio of 1:1000 and incubated overnight. The secondary

(5) Alternatively activated macrophages are associated with the α2AP production that occurs with the development of dermal fibrosis : The role of alternatively activated macrophages on the development of fibrosisArthritis research & therapyApril 10, 2020Kanno Y, Shu E, Niwa H, Kanoh H, Seishima M.

(6) RPN2 promotes metastasis of hepatocellular carcinoma cell and inhibits autophagy via STAT3 and NF-κB pathwaysAgingSeptember 3, 2019Huang L, Jian Z, Gao Y, Zhou P, Zhang G, Jiang B, Lv Y.

(7) N-(2'-Hydroxyphenyl)-2-propylpentanamide (OH-VPA), a histone deacetylase inhibitor, induces the release of nuclear HMGB1 and modifies ROS levels in HeLa cellsOncotargetSeptember 7, 2018Contis-Montes de Oca A, Rodarte-Valle E, Rosales-Hernández MC, Abarca-Rojano E, Rojas-Hernández S, Fragoso-Vázquez MJ, Mendieta-Wejebe JE, Correa-Basurto AM, Vázquez-Moctezuma I, Correa-Basurto J.(PBS TweenTriton 0.5%). Subsequently, cells were washed and primary antibodies, including anti-HMGB1 (GTX101277, GeneTex, USA) and anti-β Actin (ab8229, Abcam, USA), were added at a ratio of 1:1000 and incubated

(8) HMGB1/IL-1β complexes regulate neuroimmune responses in alcoholismBrain, behavior, and immunityAugust 1, 2018Coleman LG Jr, Zou J, Qin L, Crews FT.

(9) PARP-1 protects against colorectal tumor induction, but promotes inflammation-driven colorectal tumor progressionProceedings of the National Academy of Sciences of the United States of AmericaApril 24, 2018Dörsam B, Seiwert N, Foersch S, Stroh S, Nagel G, Begaliew D, Diehl E, Kraus A, McKeague M, Minneker V, et al.cyclin D1 (2978, 1:50; Cell Signaling Technology), F4/80 (BM4007, 1:400; Acris Antibodies), HMGB1 (GTX101277, 1:400; GeneTex), LC3B (3868, 1:250; Cell Signaling Technology), PCNA (sc-56, 1:400; Santa Cruz Biotechnology),

(10) Heparanase regulates the M1 polarization of renal macrophages and their crosstalk with renal epithelial tubular cells after ischemia/reperfusion injuryFASEB journal : official publication of the Federation of American Societies for Experimental BiologyFebruary 1, 2018Masola V, Zaza G, Bellin G, Dall'Olmo L, Granata S, Vischini G, Secchi MF, Lupo A, Gambaro G, Onisto M.

(11) MicroRNA-200c inhibits epithelial-mesenchymal transition, invasion, and migration of lung cancer by targeting HMGB1PloS oneJanuary 1, 2017Liu PL, Liu WL, Chang JM, Chen YH, Liu YP, Kuo HF, Hsieh CC, Ding YS, Chen WW, Chong IW.

(12) ASC filament formation serves as a signal amplification mechanism for inflammasomesNature communicationsJune 22, 2016Dick MS, Sborgi L, Rühl S, Hiller S, Broz P.

(13) Resources for the Comprehensive Discovery of Functional RNA ElementsMolecular cellMarch 17, 2016Sundararaman B, Zhan L, Blue SM, Stanton R, Elkins K, Olson S, Wei X, Van Nostrand EL, Pratt GA, Huelga SC, et al.

(14) Simultaneous induction of apoptosis and necroptosis by Tanshinone IIA in human hepatocellular carcinoma HepG2 cellsCell death discoveryJanuary 1, 2016Lin CY, Chang TW, Hsieh WH, Hung MC, Lin IH, Lai SC, Tzeng YJ.

(15) Dual therapeutic functions of F-5 fragment in burn wounds: preventing wound progression and promoting wound healing in pigsMolecular therapy. Methods & clinical developmentJanuary 1, 2016Bhatia A, O'Brien K, Chen M, Wong A, Garner W, Woodley DT, Li W.Immunohistochemistry studies on skin wounds were conducted with anti-HMGB1 antibody for necrosis (1:100, GTX101277, GeneTex, Irvine, CA), anti-activated caspase 3a antibody for apoptosis (1:200, GTX61121, GeneTex).

(16) Caspase-11 activates a canonical NLRP3 inflammasome by promoting K(+) effluxEuropean journal of immunologyOctober 1, 2015Rühl S, Broz P.

(17) Shikonin-enhanced cell immunogenicity of tumor vaccine is mediated by the differential effects of DAMP componentsMolecular cancerSeptember 24, 2015Lin TJ, Lin HT, Chang WT, Mitapalli S P, Hsiao PW, Yin SY, Yang NS.

(18) High-mobility group box 1 expression and lymph node metastasis in intrahepatic cholangiocarcinomaWorld journal of gastroenterologyMarch 21, 2015Xu YF, Ge FJ, Han B, Yang XQ, Su H, Zhao AC, Zhao MH, Yang YB, Yang J.heat-mediated retrieval by microwave for 15 min. The slides were incubated with primary antibodies for HMGB1 (GTX101277, 1:500; GeneTex Inc., Irvine, CA, United States) and VEGF-C (ab9546, 1:500; Abcam, Cambridge, United

(19) Receptor for Advanced Glycation End Products and its Inflammatory Ligands are Upregulated in Amyotrophic Lateral SclerosisFrontiers in cellular neuroscienceJanuary 1, 2015Juranek JK, Daffu GK, Wojtkiewicz J, Lacomis D, Kofler J, Schmidt AM.anti-RAGE (GTX23611, 1:1000, GeneTex); rabbit anti-S100B (ab52642, 1:5000, Abcam); and rabbit anti-HMGB1 (GTX101277, 1:1000, GeneTex). After incubation with indicated antibodies, protein signals were visualized with

(20) Amitriptyline pharmacologically preconditions rat hearts against cardiac ischemic-reperfusion injuryInternational journal of cardiologyJanuary 1, 2015Lee SM, Hutchinson M, Staikopoulos V, Saint DA.

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Anti-HMGB1 antibody

Anti-HMGB1 antibody

Anti-HMGB1 antibody

Anti-HMGB1 antibody from GeneTex

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GeneTex

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Anti-HMGB1 antibody from GeneTex

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