Anti-MUC2 antibody [C3], C-term GTX100664 from GeneTex

Product Specs
ItemAnti-MUC2 antibody [C3], C-term
CompanyGeneTex
Price $169.00Supplier Page
Catalog NumberGTX100664
ReactivityHuman, Mouse, Rat, Pig
Quantity25 µl
ClonalityPolyclonal
Conjugate/TagUnconjugated
ApplicationsWB, ICC/IF, IHC-P, IHC-Fr
FormatPBS, 20% Glycerol, 0.025% ProClin 300
HostRabbit
ImmunogenCarrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human MUC2. The exact sequence is proprietary
Concentration1.43mg/ml
IsotypeIgG
Antibody TypePrimary Antibodies
NCBI Full Gene Namemucin 2, oligomeric mucus/gel-forming
NCBI Gene Aliasesmucin 2, oligomeric mucus/gel-forming, MLP, MUC-2, SMUC, MUC-2, MLP, SMUC
PurityPurified by antigen-affinity chromatography
TargetMUC2
Research AreaCancer, Cell Biology, Tumor Markers
Gene NameMUC2
Molecular Weight540

Questions and Answers

Can this antibody be used for immunofluorescence applications in my studies on intestinal inflammation?

Yes, the Anti-MUC2 antibody [C3], C-term has been shown to work in immunofluorescence applications. For instance, it was utilized to stain Caco-2 cells and intestinal tissues in studies investigating the role of MUC2 in various gastrointestinal conditions, highlighting its effectiveness in visualizing mucin expression in these contexts.

Is this antibody effective for detecting MUC2 in mouse models of colitis?

The Anti-MUC2 antibody [C3], C-term has been cited in studies involving mouse models of colitis, where it was used to assess MUC2 expression in intestinal tissues. This suggests that it is effective for detecting MUC2 in such experimental setups, contributing to the understanding of mucin dynamics during inflammatory bowel disease.

What species can this antibody recognize, and is it suitable for cross-species studies?

This antibody recognizes MUC2 from multiple species, including human, mouse, rat, and pig. This broad reactivity makes it suitable for cross-species studies, allowing researchers to investigate MUC2 expression and function across different animal models and human samples.

Has this antibody been used in any recent research related to gastrointestinal diseases?

Yes, the Anti-MUC2 antibody [C3], C-term has been referenced in recent studies focusing on gastrointestinal diseases, including its role in mucosal barrier function and inflammation. For example, it was used in research examining the effects of dietary components on MUC2 expression in the context of inflammatory bowel disease, demonstrating its relevance in current gastrointestinal research.

GeneTex

GeneTex, Inc. 2456 Alton Parkway

Irvine, California 92606

United States

Phone: 1-877-GeneTex (436-3839) or 949-553-1900
Fax: 949-309-2888

Company Profile

Website: http://www.genetex.com

(1) The HUNT study identifies host genetic factors reproducibly associated with human gut microbiota compositionNature GeneticsFebruary 13, 2026Marta Riise Moksnes, Eivind Coward, Maria Nethander, Koen Dekkers, Louise Grahnemo, Anna E. Törnqvist, Lei Li, Per Lundmark, Kamalita Pertiwi, Gabriel Baldanzi, et al.antibodies against either EpCAM (1:250, Abcam, ab71916, lot #1076051-3) and MUC2-C3 (1:100, GeneTex, GTX100664, lot #44818) or EpCAM and MUC12-S2 (1:250), which were diluted in blocking serum and left to incubate

(2) Bacteroides intestinalis -Driven Arabinoxylan Fermentation Mitigates Inflammatory and Metabolic DysfunctionbioRxivFebruary 11, 2026Wenyan Zhou, Ka Lam Nguyen, Ka Lam Nguyen, Yuexi Chen, Yuexi Wang, David M. Bianchi, Weihao Bianchi, Shanny Hsuan Kuo, Shanny Gharieb, Emily Tung, et al.for 20 minutes. Sections were incubated overnight at 4°C with a rabbit anti-MUC2 antibody (Genetex, GTX100664) diluted in PBS containing 5% normal serum and 1% BSA. Detection was performed using Alexa Fluor 488-conjugated

(3) The RNA-binding protein Imp1 promotes a Spdef transcriptional program and mucus fucosylation during necrotizing enterocolitisbioRxivJanuary 31, 2026Kevin A. Swift, Alexandria J. Shumway, Molly Aloia, Madeline Hedges, Rachel Pung, Cariam Rodriguez Santiago, Michael Shanahan, Alexander Drake, Melanie H. Hakar, Leigh Selesner, et al.Bioreagents, Waltman, MA) in PBS for 90 minutes at room temperature. Slides were incubated with anti-Muc2, GTX100664, (GeneTex, Irvine, CA) overnight at 4 °C. Following three washes with PBS, sections were incubated with

(4) Local Interactions Between Innate Immune Signaling, Microbiota, and Bile Acids Drive the Development of Duodenal AdenomasCellular and Molecular Gastroenterology and HepatologyJanuary 1, 2026Juan F. Burgueño, Hajar Hazime, Julia Fritsch, Gillian E. Jacobsen, Henry D. Dione, Trevor Cickovski, Eddy E. González, Ana M. Santander, Irina Fernández, Nivis Brito, et al.(SP6),Abcam,Ab16667,IHC,1/100 Rabbit anti-MPO,Abcam,Ab9535,IHC,1/50 Rabbit anti-MUC2 (C3),GeneTex,GTX100664,IHC,1/1000 Rabbit anti-phospho γH2AX,Cell Signaling,9718,IHC,1/250 Rabbit anti-mouse S100A8 (EPR3554),Novus Biological

(5) Gut microbiota dysbiosis affects intestinal sensitivity through epithelium-to-neuron signaling: novel insights from a colon organoid-based model to improve visceral pain therapyGut microbesDecember 1, 2025Margiotta F, Lucarini E, Toti A, Curti L, Masi A, Mello T, Le Gall G, Mattei G, Magi A, Vauzour D, et al.E-Cadherin (AF748, Lot CYG0420091, R&D Systems-Bio-Techne, Milan, Italy); 1:200 Rabbit anti-Mouse Mucin 2 (GTX100664, Lot 44,447, GeneTex, Irvine, CA, USA); 1:100 Rabbit anti-Mouse Carbonic Anhydrase IV (PA5-81329, Lot

(6) Maternal emulsifier consumption alters the offspring early-life microbiota and goblet cell function leading to long-lasting diseases susceptibilityNat CommunJuly 29, 2025Clara Delaroque, Héloïse Rytter, Erica Bonazzi, Marine Huillet, Sandrine Ellero-Simatos, Eva Chatonnat, Fuhua Hao, Andrew Patterson, Benoit Chassaingin PBS) was added for 30 min at 4 °C. Mucin-2 primary antibody (rabbit H-300, [C3], C-term, Genetex, GTX100664) was diluted to 1:100 in block solution and applied overnight at 4 °C. After washing 3 × 10 min in PBS,

(7) Goblet Cell Loss Linked to NOD2 and Secondary Resection in Crohn’s Disease Is Induced by Dysbiosis and Epithelial MyD88Cellular and Molecular Gastroenterology and HepatologyMay 14, 2025Serre-Yu Wong, Maria Manuela Estevinho, Thomas Heaney, Allison A. Marshall, Elisabeth Giselbrecht, Scott G. Daniel, Chaoting Zhou, Adriana Rosas-Villegas, Kyung Ku Jang, Hairu Yang, et al.and cell conditioning. Single staining was performed using the primary antibody (MUC2 antibody [C3] GTX100664 [1:50], GeneTex, and Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP® Rabbit mAb #4370 [1:2000],

(8) In vitro microbiota model recapitulates and predicts individualised sensitivity to dietary emulsifierGutApril 7, 2025Rytter H, Naimi S, Wu G, Lewis J, Duquesnoy M, Vigué L, Tenaillon O, Belda E, Vazquez-Gomez M, Touly N, et al.used to mark around the section. Mucin-2 primary antibody (rabbit MUC2 antibody (C3), C-term, Genetex, GTX100664) was diluted 1:100 in block solution and applied overnight at 4°C. After washing 3×10 min in PBS, block

(9) Hirsutella sinensis polysaccharides and Parabacteroides goldsteinii reduce lupus severity in imiquimod-treated miceBiomedical journalApril 1, 2025Chang SH, Ko YF, Liau JC, Wu CY, Hwang TL, Ojcius DM, Young JD, Martel J.were hybridized with antibodies directed against claudin-3 (GTX00665), occludin (GTX114949), mucin-2 (GTX100664), and ZO-1 (GTX108592), all purchased from GeneTex (Irvine, USA). Cell nuclei were counterstained with

(10) The Ulcerative Colitis-Associated Gene NXPE1 Catalyzes Glycan Modifications on Colonic MucinJournal of the American Chemical SocietyMarch 26, 2025Ranad Humeidi, Noriko Oshiro-Rapley, Xiebin Gu, Joon Soo An, Ashwin N. Ananthakrishnan, Elizabeth A. Creasey, Mark J. Daly, Stuart L. Schreiber, Daniel B. Graham, Mohammad R. Seyedsayamdost, et al.(Cell Signaling Technology, #5033), GM130 (abcam, #ab52649), CCDC186 (Novus Bio NBP1–90440), and MUC2 (GeneTex, #GTX100664) in IF buffer at 4°C overnight. Cells were washed and incubated with Alexa plus 488- or Alexa plus 594-conjugated

(11) PIEZO-dependent mechanosensing is essential for intestinal stem cell fate decision and maintenanceScience (New York, N.Y.)November 29, 2024Baghdadi MB, Houtekamer RM, Perrin L, Rao-Bhatia A, Whelen M, Decker L, Bergert M, Pérez-Gonzàlez C, Bouras R, Gropplero G, et al.

(12) Itaconic Acid Alleviates Perfluorooctanoic Acid-Induced Oxidative Stress and Intestinal Damage by Regulating the Keap1/Nrf2/Ho-1 Pathway and Reshaping the Gut MicrobiotaInternational journal of molecular sciencesSeptember 11, 2024Wu L, Hu Z, Luo X, Ge C, Lv Y, Zhan S, Huang W, Shen X, Yu D, Liu B.temperature. Occludin antibody (dilution 1:500, 27260-1-AP, Proteintech), MUC-2 antibody (dilution 1:500, gtx100664, Genetex, Irvine, CA, USA), and Nrf2 antibody (dilution 1:500, 16396-1-AP, Proteintech, Sankt Leon-Rot,

(13) Therapeutic potential of the secreted Kazal-type serine protease inhibitor SPINK4 in colitisNature communicationsJuly 12, 2024Wang Y, Han J, Yang G, Zheng S, Zhou G, Liu X, Cao X, Li G, Zhang B, Xie Z, et al.

(14) Stress-induced mucin 13 reductions drive intestinal microbiome shifts and despair behaviorsBrain, behavior, and immunityJuly 1, 2024Rivet-Noor CR, Merchak AR, Render C, Gay NM, Beiter RM, Brown RM, Keeler A, Moreau GB, Li S, Olgun DG, et al.stained with 1:1000 Mucin 13 (G-10) (Santa Cruz Biotechnology #sc-390115) and 1:1000 Mucin 2 (GeneTex #GTX100664) overnight at 4 °C in blocking solution (1x PBS, 0.5 g bovine serum albumin, 0.5 % Triton X-100) + 2

(15) TLR7-dependent eosinophil degranulation links psoriatic skin inflammation to small intestinal inflammatory changes in miceExperimental & molecular medicineMay 1, 2024Kim HJ, Jang J, Na K, Lee EH, Gu HJ, Lim YH, Joo SA, Baek SE, Roh JY, Maeng HJ, et al.incubated overnight with mucin 2 polyclonal antibody (1:200 dilution, GeneTex, Irvine, CA, USA; cat# GTX100664) or occludin polyclonal antibody (1:100 dilution, Thermo Fisher Scientific, Waltham, MA, USA; cat# 40-4700).

(16) Gut-liver axis calibrates intestinal stem cell fitnessCellFebruary 15, 2024Girak Kim, Zuojia Chen, Jian Li, Jialie Luo, Felipe Angeles Castro Castro-Martinez, Jan Wisniewski, Kairong Cui, Yan Wang, Jialei Sun, Xiaobai Ren, et al.lysozyme,Proteintech,Cat# 15013-1-AP; RRID: AB_10639507 Rabbit polyclonal anti-human/mouse MUC2,GeneTex,Cat# GTX100664; RRID: AB_1950958 Rabbit polyclonal anti-human POU2F3,Sigma,Cat# HPA019652; RRID: AB_1855585 Rabbit

(17) Dietary emulsifier consumption accelerates type 1 diabetes development in NOD miceNPJ biofilms and microbiomesJanuary 6, 2024Delaroque C, Chassaing B.in PBS) was added for 30 min at 4 °C. Mucin-2 primary antibody (rabbit H-300, [C3], C-term, Genetex, GTX100664) was diluted to 1:100 in block solution and applied overnight at 4 °C. After washing 3 × 10 min in PBS,

(18) Fecal let-7b and miR-21 directly modulate the intestinal microbiota, driving chronic inflammationGut microbesJanuary 1, 2024Casado-Bedmar M, Roy M, Berthet L, Hugot JP, Yang C, Manceau H, Peoc'h K, Chassaing B, Merlin D, Viennois E.solution (5% fetal bovine serum in PBS) for 30 min at 4°C. Rabbit mucin-2 primary antibody (1:100, GTX100664, Genetex) was incubated overnight at 4°C. After washing in PBS (3 × 10 min), secondary anti-rabbit Alexa

(19) Innate mechanism of mucosal barrier erosion in the pathogenesis of acquired colitisiScienceOctober 20, 2023Yang WH, Aziz PV, Heithoff DM, Kim Y, Ko JY, Cho JW, Mahan MJ, Sperandio M, Marth JD.

(20) MRTF-A gain-of-function in mice impairs homeostatic renewal of the intestinal epitheliumCell death & diseaseSeptember 28, 2023Singh AK, Rai A, Weber A, Gericke M, Janssen KP, Moser M, Posern G.Sodium citrate, 0.05% Tween 20, pH 6.0) for 30 min prior to incubation with Muc2 antibodies (1:500, GTX100664, GeneTex). Additional antibodies used were cleaved caspase-3 (1:500, #9664, Cell Signaling, Leiden,

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Anti-MUC2 antibody [C3], C-term

Anti-MUC2 antibody [C3], C-term

Anti-MUC2 antibody [C3], C-term

Anti-MUC2 antibody [C3], C-term

Anti-MUC2 antibody [C3], C-term

Anti-MUC2 antibody [C3], C-term from GeneTex

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Anti-MUC2 antibody [C3], C-term from GeneTex

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