Anti-LOXL2 antibody GTX105085 from GeneTex

Product Specs
ItemAnti-LOXL2 antibody
CompanyGeneTex
Price $169.00Supplier Page
Catalog NumberGTX105085
FormatPBS, 20% Glycerol, 0.025% ProClin 300
ApplicationsWB, ICC/IF, IHC-P, ELISA
ReactivityHuman
Conjugate/TagUnconjugated
ClonalityPolyclonal
Quantity25 µl
HostRabbit
ImmunogenRecombinant protein encompassing a sequence within the center region of human LOXL2. The exact sequence is proprietary
Concentration1.24mg/ml
Antibody TypePrimary Antibodies
NCBI Full Gene Namelysyl oxidase like 2
NCBI Gene AliasesLOR, lysyl oxidase like 2, LOR, LOR2, WS9-14, WS9-14, LOR2
PurityPurified by antigen-affinity chromatography
TargetLOXL2
IsotypeIgG
Research AreaCancer
Gene NameLOXL2
Molecular Weight87

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GeneTex

GeneTex, Inc. 2456 Alton Parkway

Irvine, California 92606

United States

Phone: 1-877-GeneTex (436-3839) or 949-553-1900
Fax: 949-309-2888

Company Profile

Website: http://www.genetex.com

(1) Tannic Acid Achieves Rapid Scar-Free Corneal Healing by Chelating Excess Copper to Suppress Aberrant LOX-Mediated FibrosisInvest Ophthalmol Vis SciMarch 6, 2026Maoyu Cai, Xindi Wang, Shiyi Sun, Zhengxi Yuan, Yan Wang, Xia Hua, Xiaoyong Yuanwere incubated with primary antibodies against LOX (1:1000, 17958-1-AP; Proteintech), LOXL2 (1:1000, GTX105085; GeneTex), CTR1 (1:5000, 67221-1-Ig; Proteintech), VIM (1:20000, 60330-1-Ig; Proteintech), α-SMA (1:5000,

(2) FGF-23 facilitates osteosarcoma metastasis by modulating the miR-4463/LOXL2 axis expression via the ERK, p38, and JNK signaling pathwayInternational Journal of Medical SciencesJanuary 1, 2026Chun-Han Hou, Chih-Yang LinCA, USA",Mouse,1:1000 JNK,,#9252,"Cell Signaling Technology, Danvers, MA, USA",Rabbit,1:1000 LOXL2,,GTX105085,"GeneTex, Hsinchu, Taiwan",Rabbit,1:1000 FGF-23,,PA5-121994,"Invitrogen, Carlsbad, CA, USA",Rabbit,1:1000 β-actin,,A5441,"Sigma-Aldrich,

(3) Pharmacological targeting of the mitochondrial calcium-dependent potassium channel KCa3.1 triggers cell death and reduces tumor growth and metastasis in vivoCell death & diseaseDecember 20, 2022Bachmann M, Rossa A, Varanita T, Fioretti B, Biasutto L, Milenkovic S, Checchetto V, Peruzzo R, Ahmad SA, Patel SH, et al.Cell Signaling Technologies (CST) #2535), α-HIF-1α (1:500 in TTBS, Genetex #GTX127309), α-LOXL-2 (1:1000 in TTBS, Genetex #GTX105085), α-Total OXPHOS Rodent WB Antibody Cocktail (1:3000 in TTBS, Abcam #ab110413), TOM-20 (1:1000 in TTBS,

(4) Reciprocal regulation of LOXL2 and HIF1α drives the Warburg effect to support pancreatic cancer aggressivenessCell death & diseaseNovember 26, 2021Li R, Li H, Zhu L, Zhang X, Liu D, Li Q, Ni B, Hu L, Zhang Z, Zhang Y, et al.and subjected to IHC staining. Primary antibodies used for IHC staining were LOXL2 (1:500, GeneTex, GTX105085) and PCNA (1:300, Cell Signaling Technology, #13110). Scoring was conducted based on both the ratio

(5) MIR29A Impedes Metastatic Behaviors in Hepatocellular Carcinoma via Targeting LOX, LOXL2, and VEGFAInternational journal of molecular sciencesJune 1, 2021Yang YL, Tsai MC, Chang YH, Wang CC, Chu PY, Lin HY, Huang YH.overnight. The primary antibodies included LOX (1:1000; NB100-2527, Novus, CO, USA), LOXL2 (1:1000; GTX105085, GeneTex, Irvine, USA), VEGFA (1:1000; ab46154, Abcam, Cambridge, UK), caspase 9 (1:1000; 10380-1-AP,

(6) Microarray expression profile of mRNAs and long noncoding RNAs and the potential role of PFK-1 in infantile hemangiomaCell divisionJanuary 11, 2021Yang K, Zhang X, Chen L, Chen S, Ji Y.Sections were blocked for 30 min in 5% serum at room temperature. Primary antibodies against LOXL2 (1:100, GTX105085, GeneTex) and PFK-1 (1:50, sc-377346, Santa Cruz) were added for incubation overnight at 4 °C. Slides

(7) The Expression Patterns and Roles of Lysyl Oxidases in Aortic DissectionFrontiers in cardiovascular medicineJanuary 1, 2021Yi X, Zhou Y, Chen Y, Feng X, Liu C, Jiang DS, Geng J, Li X, Jiang X, Fang ZM.(ab182858) which were bought from Abcam. LOXL1 (A10191) and LOXL4 (A13131) were got from ABclonal. LOXL2 (GTX105085), MMP2 (GTX634832), MMP9 (GTX100458), H3K9me3 (GTX121677), and PCNA (GTX100539) were purchased from

(8) LOXL2 promotes aggrecan and gender-specific anabolic differences to TMJ cartilageScientific reportsNovember 19, 2020Tashkandi MM, Alsaqer SF, Alhousami T, Ali F, Wu YC, Shin J, Mehra P, Wolford LM, Gerstenfeld LC, Goldring MB, et al.

(9) Mechanical injury and IL-1β regulated LOXs and MMP-1, 2, 3 expression in ACL fibroblasts co-cultured with synoviocytesBiotechnology lettersAugust 1, 2020Wang C, Chi Q, Sha Y, Xu K, Xu C, Chen C, Huang W, Chen P, Chen P, Yang L, et al.

(10) LOXL2 Expression Status Is Correlated With Molecular Characterizations of Cervical Carcinoma and Associated With Poor Cancer Survival via Epithelial-Mesenchymal Transition (EMT) PhenotypeFrontiers in oncologyJanuary 1, 2020Cao C, Lin S, Zhi W, Lazare C, Meng Y, Wu P, Gao P, Wei J, Wu P.Tris-EDTA (PH 9.0) using heat-induced protocol. And the slides were incubated at 4°C with LOXL2 antibody (GTX105085, GeneTex, 1:400) overnight. Staining detection was performed using DAB (Servicebo). Characteristics

(11) Withaferin A reverses bile duct ligation-induced liver fibrosis by modulating extracellular matrix deposition: Role of LOXL2/Snail1, vimentin, and NFκB signalingBioFactors (Oxford, England)November 1, 2019Sayed N, Khurana A, Saifi MA, Singh M, Godugu C.

(12) Mechanism for oral tumor cell lysyl oxidase like-2 in cancer development: synergy with PDGF-ABOncogenesisMay 13, 2019Mahjour F, Dambal V, Shrestha N, Singh V, Noonan V, Kantarci A, Trackman PC.Abcam) or anti-proliferating cell nuclear antigen antibody (PCNA, ab92552, Abcam), anti-LOXL2 antibody (GTX105085, GeneTex), anti-E-cadherin antibody (610181, BD Transduction Laboratories), and anti-vimentin antibody

(13) Aberrant Collagen Cross-linking in Human Oral Squamous Cell CarcinomaJournal of dental researchMay 1, 2019Saito T, Uzawa K, Terajima M, Shiiba M, Amelio AL, Tanzawa H, Yamauchi M.

(14) Multiple Functions of Lysyl Oxidase Like-2 in Oral Fibroproliferative ProcessesJournal of dental researchOctober 1, 2018Saxena D, Mahjour F, Findlay AD, Mously EA, Kantarci A, Trackman PC.concentration of 50,000 cells per well in 6-well plates. Lysyl oxidase like-2 antibody was from Genetex (GTX105085). Affinity purified LOX antibody was previously described (Khosravi et al. 2014), while LOXL1-, LOXL3-,

(15) C/EBPβ enhances platinum resistance of ovarian cancer cells by reprogramming H3K79 methylationNature communicationsApril 30, 2018Liu D, Zhang XX, Li MC, Cao CH, Wan DY, Xi BX, Tan JH, Wang J, Yang ZY, Feng XX, et al.

(16) FHL2 promotes tubular epithelial-to-mesenchymal transition through modulating β-catenin signallingJournal of cellular and molecular medicineMarch 1, 2018Cai T, Sun D, Duan Y, Qiu Y, Dai C, Yang J, He W.

(17) Anabolic role of lysyl oxidase like-2 in cartilage of knee and temporomandibular joints with osteoarthritisArthritis research & therapyAugust 2, 2017Alshenibr W, Tashkandi MM, Alsaqer SF, Alkheriji Y, Wise A, Fulzele S, Mehra P, Goldring MB, Gerstenfeld LC, Bais MV.

(18) HIF-1α promoted vasculogenic mimicry formation in hepatocellular carcinoma through LOXL2 up-regulation in hypoxic tumor microenvironmentJournal of experimental & clinical cancer research : CRApril 27, 2017Wang M, Zhao X, Zhu D, Liu T, Liang X, Liu F, Zhang Y, Dong X, Sun B.incubated with rabbit monoclonal anti-HIF-1α (ZA-0562, USA) and rabbit polyclonal anti-LOXL2 (1:800, Cat. #GTX105085; GeneTex, California, USA) primary antibodies overnight at 4 °C, and the secondary antibody was incubated

(19) Comparative analysis of lysyl oxidase (like) family members in pulmonary fibrosisScientific reportsMarch 10, 2017Aumiller V, Strobel B, Romeike M, Schuler M, Stierstorfer BE, Kreuz S.UK) (dilution 1:300); LOXL1: NBP1-82827, (Acris Antibodies GmbH, Germany) (dilution 1:100), LOXL2: GTX105085 (GeneTex Inc., Irvine, CA) (dilution 1:500), LOXL3: LS-C165846 (LSBio, Seattle, WA) (dilution 1:500),

(20) Orthotopic non-metastatic and metastatic oral cancer mouse modelsOral oncologyMay 1, 2015Bais MV, Kukuruzinska M, Trackman PC.#610181), MT-MMP1 (Abcam Inc;ab51074) DPAGT1 (Covance Research Products, Inc [20]) and LOXL2 (GeneTex #GTX105085). Statistical analysis All experiments were analyzed using two way ANOVA with Bonferroni post hoc

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Anti-LOXL2 antibody

Anti-LOXL2 antibody

Anti-LOXL2 antibody

Anti-LOXL2 antibody from GeneTex

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Anti-LOXL2 antibody from GeneTex

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