Anti-HMGA2 antibody - ChIP grade GTX100519 from GeneTex

Product Specs
ItemAnti-HMGA2 antibody - ChIP grade
CompanyGeneTex
Price $169.00Supplier Page
Catalog NumberGTX100519
ClonalityPolyclonal
ReactivityHuman, Mouse, Rat
ApplicationsWB, ICC/IF, IHC-P, IP, ChIP assay
HostRabbit
FormatPBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300
Quantity25 µl
Conjugate/TagUnconjugated
ImmunogenRecombinant protein encompassing a sequence within the center region of human HMGA2. The exact sequence is proprietary
Concentration0.13mg/ml
IsotypeIgG
Antibody TypePrimary Antibodies
NCBI Full Gene Namehigh mobility group AT-hook 2
NCBI Gene AliasesHMGIC, SRS5, BABL, LIPO, HMGI-C, STQTL9, high mobility group AT-hook 2, BABL, HMGI-C, HMGIC, LIPO, STQTL9
PurityPurified by antigen-affinity chromatography
TargetHMGA2
Research AreaCell Biology
Gene NameHMGA2
Molecular Weight12

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GeneTex

GeneTex, Inc. 2456 Alton Parkway

Irvine, California 92606

United States

Phone: 1-877-GeneTex (436-3839) or 949-553-1900
Fax: 949-309-2888

Company Profile

Website: http://www.genetex.com

(1) Regulatory effect between HMGA2 and the Wnt/β-catenin signaling pathway in the carcinogenesis of sporadic colorectal tubular adenomaOncology lettersDecember 1, 2021Li D, Cao Y, Wang J, Yang H, Liu W, Cui J, Wu W.room temperature. Slides were then incubated with primary antibodies against HMGA2 (1:300 dilution; GTX100519; GeneTex, Irvine), Wnt (1:200 dilution; FNab09517; FineTest, Wuhan Fine Biotech Co.); β-catenin (1:50

(2) Multiple myeloma driving factor WHSC1 is a transcription target of oncogene HMGA2 that facilitates colon cancer proliferation and metastasisBiochemical and biophysical research communicationsAugust 27, 2021Liu HH, Lee CH, Hsieh YC, Hsu DW, Cho EC.

(3) HMGA1B/2 transcriptionally activated-POU1F1 facilitates gastric carcinoma metastasis via CXCL12/CXCR4 axis-mediated macrophage polarizationCell death & diseaseApril 29, 2021Tang C, Lei X, Xiong L, Hu Z, Tang B.

(4) E-cadherin Interacts With Posttranslationally-Modified AGO2 to Enhance miRISC ActivityFrontiers in cell and developmental biologyJanuary 1, 2021Li JN, Sun HL, Wang MY, Chen PS.

(5) Identification of HMGA2 inhibitors by AlphaScreen-based ultra-high-throughput screening assaysScientific reportsNovember 2, 2020Su L, Bryan N, Battista S, Freitas J, Garabedian A, D'Alessio F, Romano M, Falanga F, Fusco A, Kos L, et al.

(6) New molecular insights into the pathogenesis of lipoblastomas: clinicopathologic, immunohistochemical, and molecular analysis in pediatric casesHuman pathologyOctober 1, 2020Lopez-Nunez O, Alaggio R, Ranganathan S, Schmitt L, John I, Church AJ, Picarsic J.

(7) An HMGA2-p62-ERα axis regulates uterine leiomyomas proliferationFASEB journal : official publication of the Federation of American Societies for Experimental BiologyAugust 1, 2020Liu B, Chen G, He Q, Liu M, Gao K, Cai B, Qu J, Lin S, Geng A, Li S, et al.

(8) The regulation of acetylation and stability of HMGA2 via the HBXIP-activated Akt-PCAF pathway in promotion of esophageal squamous cell carcinoma growthNucleic acids researchMay 21, 2020Wu Y, Wang X, Xu F, Zhang L, Wang T, Fu X, Jin T, Zhang W, Ye L.

(9) Dicoumarol suppresses HMGA2-mediated oncogenic capacities and inhibits cell proliferation by inducing apoptosis in colon cancerBiochemical and biophysical research communicationsApril 16, 2020Chen CH, Hsieh YC, Yang PM, Liu YR, Cho EC.

(10) Metformin alleviates breast cancer through targeting high-mobility group AT-hook 2Thoracic cancerMarch 1, 2020Li Y, Wang D, Ren H, Feng W.

(11) An Integrated Bioinformatics Analysis Repurposes an Antihelminthic Drug Niclosamide for Treating HMGA2-Overexpressing Human Colorectal CancerCancersOctober 2, 2019Leung SW, Chou CJ, Huang TC, Yang PM.

(12) Tetrac downregulates β-catenin and HMGA2 to promote the effect of resveratrol in colon cancerEndocrine-related cancerMarch 1, 2018Nana AW, Chin YT, Lin CY, Ho Y, Bennett JA, Shih YJ, Chen YR, Changou CA, Pedersen JZ, Incerpi S, et al.were individually incubated for overnight with COX-2 (Santa Cruz 1745 1:200 dilution), HMGA2 (Genetex GTX100519; 1:200 dilution), β-catenin (BD Bioscience 1:200 dilution) or chibby family member 1 ((s-13) Sc-86379

(13) Replication stress-induced endogenous DNA damage drives cellular senescence induced by a sub-lethal oxidative stressNucleic acids researchOctober 13, 2017Venkatachalam G, Surana U, Clément MV.rabbit-Lamin B1 (#ab16048) and rabbit-MPG (#ab155092) were purchased from Abcam. Rabbit-HMGA2 antibody (#GTX100519) was purchased from GeneTex. Mouse-PAR antibody (#ALX-804–220-R100) was purchased from Enzo lifesciences.

(14) Effect of RNA interference of the expression of HMGA2 on the proliferation and invasion ability of ACHN renal cell carcinoma cellsMolecular medicine reportsOctober 1, 2017Liu Y, Fu QZ, Pu L, Song LL, Wang YY, Liu J, Wang ZL, Wang ZM.Thermo Fisher Scientific, Inc. (Waltham, MA, USA). Mouse anti-human HMGA2 monoclonal antibody (cat.no: GTX100519) was purchased form GeneTex, Inc. (Irvine, CA, USA) and the secondary goat anti-mouse IgG antibody (cat

(15) The long noncoding RNA HULC promotes liver cancer by increasing the expression of the HMGA2 oncogene via sequestration of the microRNA-186The Journal of biological chemistrySeptember 15, 2017Wang Y, Chen F, Zhao M, Yang Z, Li J, Zhang S, Zhang W, Ye L, Zhang X.

(16) Tough decoy targeting of predominant let-7 miRNA species in adult human hematopoietic cellsJournal of translational medicineAugust 2, 2017de Vasconcellos JF, Byrnes C, Lee YT, Allwardt JM, Kaushal M, Rabel A, Miller JL.

(17) HMGA2 promotes vasculogenic mimicry and tumor aggressiveness by upregulating Twist1 in gastric carcinomaScientific reportsMay 22, 2017Sun J, Sun B, Sun R, Zhu D, Zhao X, Zhang Y, Dong X, Che N, Li J, Liu F, et al.Primer sequences are listed in the Table S3. Antibodies used for the ChIP assays included anti-HMGA2 (GTX100519, GeneTex, USA) and irrelevant IgG control antibody (AB171870, Abcam, UK). Cell invasion and migration

(18) The Fragment HMGA2-sh-3p20 from HMGA2 mRNA 3'UTR Promotes the Growth of Hepatoma Cells by Upregulating HMGA2Scientific reportsMay 18, 2017Wang Y, Chen F, Yang Z, Zhao M, Zhang S, Gao Y, Feng J, Yang G, Zhang W, Ye L, et al.

(19) TRIM71 suppresses tumorigenesis via modulation of Lin28B-let-7-HMGA2 signalingOncotargetNovember 29, 2016Yin J, Kim TH, Park N, Shin D, Choi HI, Cho S, Park JB, Kim JH.

(20) MiR-107 suppresses proliferation of hepatoma cells through targeting HMGA2 mRNA 3'UTRBiochemical and biophysical research communicationsNovember 18, 2016Wang Y, Chen F, Zhao M, Yang Z, Zhang S, Ye L, Gao H, Zhang X.

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Anti-HMGA2 antibody - ChIP grade

Anti-HMGA2 antibody - ChIP grade

Anti-HMGA2 antibody - ChIP grade

Anti-HMGA2 antibody - ChIP grade from GeneTex

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Anti-HMGA2 antibody - ChIP grade from GeneTex

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