Anti-HDAC2 antibody GTX109642 from GeneTex

Product Specs
ItemAnti-HDAC2 antibody
CompanyGeneTex
Price $169.00Supplier Page
Catalog NumberGTX109642
Quantity25 µl
Conjugate/TagUnconjugated
ApplicationsWB, ICC/IF, IHC-P, IP, ChIP assay
FormatPBS, 20% Glycerol, 0.025% ProClin 300
Concentration0.83mg/ml
ReactivityHuman, Mouse, Rat, Xenopus tropicalis
HostRabbit
PurityPurified by antigen-affinity chromatography
TargetHDAC2
IsotypeIgG
Molecular Weight55
ClonalityPolyclonal
ImmunogenCarrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human HDAC2. The exact sequence is proprietary
Antibody TypePrimary Antibodies
NCBI Full Gene Namehistone deacetylase 2
NCBI Gene AliasesRPD3, histone deacetylase 2, HD2, KDAC2, RPD3, YAF1, KDAC2, HD2, YAF1
Research AreaEpigenetics
Gene NameHDAC2

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GeneTex

GeneTex, Inc. 2456 Alton Parkway

Irvine, California 92606

United States

Phone: 1-877-GeneTex (436-3839) or 949-553-1900
Fax: 949-309-2888

Company Profile

Website: http://www.genetex.com

(1) Fructose-2,6-bisphosphate restores TDP-43 pathology-driven genome repair deficiency in motor neuron diseasesCommunications BiologyMarch 10, 2026Anirban Chakraborty, Joy Mitra, Vikas H. Malojirao, Manohar Kodavati, Santi M. Mandal, Satkarjeet K. Gill, Sravan Gopalkrishnashetty Sreenivasmurthy, Velmarini Vasquez, Mikita Mankevich, Ludo Van Den Bosch, et al.GTX108335), PNKP (BioBharati Life Science, BB-AB0105), TDP-43 (Protein tech, 10782-2-AP) and HDAC2 (GeneTex, GTX109642); all used in 1:500 dilution. For IB with insoluble fractionates, the pellet from the soluble fractionation

(2) F2,6BP restores mitochondrial genome integrity in Huntington’s diseaseJournal of Biological ChemistryMarch 1, 2026Anirban Chakraborty, Santi M. Mandal, Mikita Mankevich, Rajam S. Mani, Shandy Shahabi, Manohar Kodavati, Sravan Gopalkrishnashetty Sreenivasmurthy, Nisha Tapryal, Dale J. Hamilton, Balaji Krishnan, et al.their purity was checked by immunoblotting with GAPDH (BB-AB0060 BioBharati Life Science) and HDAC2 (GTX109642, GeneTex) antibodies (Abs), respectively. The antibodies were validated by the respective vendors. Immunopulldown

(3) F2,6BP restores mitochondrial genome integrity in Huntington's DiseasebioRxiv : the preprint server for biologyNovember 4, 2024Chakraborty A, Mandal SM, Mankevich M, Sreenivasmurthy SG, Hegde ML, Krishnan B, Ghosh G, Hazra T.their purity were checked by immunoblotting with GAPDH (BB-AB0060 BioBharati Life Science) and HDAC2 (GTX109642, GeneTex) antibodies, respectively. Human tissue samples Deidentified human post-mortem frontal cortex

(4) Nerve injury augments Cacna2d1 transcription via CK2-mediated phosphorylation of the histone deacetylase HDAC2 in dorsal root gangliaThe Journal of biological chemistryNovember 1, 2024Ghosh K, Huang Y, Chen SR, Pan HL.protein G agarose fast flow beads (#16–266, Millipore Sigma) and 2 μg of rabbit anti-HDAC2 antibody (#GTX109642, GeneTex) or normal rabbit IgG (#2729S, Cell Signaling Technology, Danvers, MA). Following incubation,

(5) Fructose-2,6-bisphosphate restores DNA repair activity of PNKP and ameliorates neurodegenerative symptoms in Huntington's diseaseProceedings of the National Academy of Sciences of the United States of AmericaSeptember 24, 2024Chakraborty A, Sreenivasmurthy SG, Miller W, Huai W, Biswas T, Mandal SM, Boscá L, Krishnan B, Ghosh G, Hazra T.depletion of individual proteins by immunoblot analysis using specific Abs. HDAC2 (Histone deacetylase 2; GTX109642, GeneTex) was used as nuclear loading control. Coimmunoprecipitation (Co-IP). Approximately 100 mg

(6) HDAC3 genetic and pharmacologic inhibition radiosensitizes fusion positive rhabdomyosarcoma by promoting DNA double-strand breaksCell death discoveryAugust 6, 2024Cassandri M, Porrazzo A, Pomella S, Noce B, Zwergel C, Aiello FA, Vulcano F, Milazzo L, Camero S, Pajalunga D, et al.

(7) Fructose-2,6-bisphosphate restores DNA repair activity of PNKP and ameliorates neurodegenerative symptoms in Huntington's diseasebioRxiv : the preprint server for biologyJuly 16, 2024Chakraborty A, Sreenivasmurthy SG, Miller W, Huai W, Biswas T, Mandal SM, Boscá L, Krishnan B, Ghosh G, Hazra T.depletion of individual proteins by immunoblot analysis using specific Abs. HDAC2 (Histone deacetylase 2; GTX109642, GeneTex) was used as loading controls. Co-immunoprecipitation (Co-IP) Approximately 100 mg of brain

(8) Site-specific acetylation of polynucleotide kinase 3'-phosphatase regulates its distinct role in DNA repair pathwaysNucleic acids researchMarch 21, 2024Islam A, Chakraborty A, Sarker AH, Aryal UK, Pan L, Sharma G, Boldogh I, Hazra T.(H5),Biolegend,920 202,1:500 p300,Active Motif,61 401,1:500 GAPDH,GeneTex,GTX100118,1:7000 HDAC2,GeneTex,GTX109642,1:500 XRCC1,GeneTex,GTX111712,1:500 XRCC4,GeneTex,GTX109632,1:500 DNA ligase III,In house (18),,1:500 DNA

(9) The DNA glycosylase NEIL2 is protective during SARS-CoV-2 infectionNature communicationsDecember 9, 2023Tapryal N, Chakraborty A, Saha K, Islam A, Pan L, Hosoki K, Sayed IM, Duran JM, Alcantara J, Castillo V, et al.generated86), NEIL1 and APE1 (in-house generated87), and HDAC2 (Histone deacetylase 2, GeneTex, catalog no. GTX109642). The membranes were extensively washed with 1% TBST followed by incubation with anti-isotype secondary

(10) Histone deacetylase 1 maintains lineage integrity through histone acetylome refinement during early embryogenesiseLifeMarch 27, 2023Zhou JJ, Cho JS, Han H, Blitz IL, Wang W, Cho KWY.then subjected to western blotting using anti-HDAC1 (Cell Signaling, 34589S), anti-HDAC2 (Genetex, GTX109642), and anti-Tubulin (Sigma, T5168). For histone modifications, acid-extracted histone lysate was prepared

(11) Novel Function of Avian p53 in Binding to ALV-J LTR Contributes to Its Antiviral RolesmBioFebruary 22, 2022Duan Y, Cao L, Yuan C, Suo X, Kong X, Gao Y, Li X, Zheng H, Wang X, Wang Q.

(12) Anti-Excitotoxic Effects of N-Butylidenephthalide Revealed by Chemically Insulted Purkinje Progenitor Cells Derived from SCA3 iPSCsInternational journal of molecular sciencesJanuary 26, 2022Yang HH, Chiang IT, Liu JW, Hsieh J, Lee JH, Lu HE, Tso HS, Deng YC, Kao JC, Wu JR, et al.(1:1000, MAB600, R&D), GAPDH (1:10,000, ab8245, Abcam), β-actin (1:5000; MAB8929, R&D), and HDAC2 (1:5000; GTX109642, GeneTex). 4.11. Statistics The statistical comparisons from at least three technical replicates and

(13) Epigenetic therapy combination of UNC0638 and CI-994 suppresses breast cancer via epigenetic remodeling of BIRC5 and GADD45ABiomedicine & pharmacotherapy = Biomedecine & pharmacotherapieJanuary 1, 2022Lin HY, Wu HJ, Chen SY, Hou MF, Lin CS, Chu PY.

(14) Intrapulmonary administration of purified NEIL2 abrogates NF-κB-mediated inflammationThe Journal of biological chemistryJanuary 1, 2021Tapryal N, Shahabi S, Chakraborty A, Hosoki K, Wakamiya M, Sarkar G, Sharma G, Cardenas VJ, Boldogh I, Sur S, et al.no. AB0020) antibodies. Anti-GAPDH (GeneTex, catalog no. GTX100118), anti-HDAC2 (GeneTex, catalog no. GTX109642), or anti-tubulin (Biobharati, Catalog no. BB-AB0119) antibodies were used as loading controls. In each

(15) The DNA Glycosylase NEIL2 Suppresses Fusobacterium-Infection-Induced Inflammation and DNA Damage in Colonic Epithelial CellsCellsAugust 28, 2020Sayed IM, Chakraborty A, Abd El-Hafeez AA, Sharma A, Sahan AZ, Huang WJM, Sahoo D, Ghosh P, Hazra TK, Das S.

(16) Hydroxygenkwanin Inhibits Class I HDAC Expression and Synergistically Enhances the Antitumor Activity of Sorafenib in Liver Cancer CellsFrontiers in oncologyJanuary 1, 2020Chen CY, Chen CC, Chuang WY, Leu YL, Ueng SH, Hsueh C, Yeh CT, Wang TH.

(17) Xanthohumol Suppresses NPC1L1 Gene Expression through Downregulation of HNF-4α and Inhibits Cholesterol Uptake in Caco-2 CellsJournal of agricultural and food chemistryOctober 9, 2019Thang SK, Chen PY, Gao WY, Wu MJ, Pan MH, Yen JH.

(18) A Tangeretin Derivative Inhibits the Growth of Human Prostate Cancer LNCaP Cells by Epigenetically Restoring p21 Gene Expression and Inhibiting Cancer Stem-like Cell ProliferationThe AAPS journalJuly 10, 2019Wei GJ, Chao YH, Tung YC, Wu TY, Su ZY.

(19) Adipose-derived Stem Cells Attenuates Diabetic Osteoarthritis via Inhibition of Glycation-mediated Inflammatory CascadeAging and diseaseJune 1, 2019Dubey NK, Wei HJ, Yu SH, Williams DF, Wang JR, Deng YH, Tsai FC, Wang PD, Deng WP.

(20) The Cholesterol-Modulating Effect of Methanol Extract of Pigeon Pea (Cajanus cajan (L.) Millsp.) Leaves on Regulating LDLR and PCSK9 Expression in HepG2 CellsMolecules (Basel, Switzerland)January 30, 2019Chang HY, Wu JR, Gao WY, Lin HR, Chen PY, Chen CI, Wu MJ, Yen JH.

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Anti-HDAC2 antibody

Anti-HDAC2 antibody

Anti-HDAC2 antibody

Anti-HDAC2 antibody

Anti-HDAC2 antibody from GeneTex

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GeneTex

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Anti-HDAC2 antibody from GeneTex

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