Anti-AKR1C1 antibody GTX105620 from GeneTex

Product Specs
ItemAnti-AKR1C1 antibody
CompanyGeneTex
Price $169.00Supplier Page
Catalog NumberGTX105620
Quantity25 µl
ApplicationsWB, ICC/IF, IHC-P, IHC
FormatPBS, 20% Glycerol, 0.025% ProClin 300
Conjugate/TagUnconjugated
Concentration0.6mg/ml
HostRabbit
ReactivityHuman, Mouse
PurityPurified by antigen-affinity chromatography
TargetAKR1C1
IsotypeIgG
Molecular Weight37
ClonalityPolyclonal
ImmunogenRecombinant protein encompassing a sequence within the center region of human AKR1C1. The exact sequence is proprietary
Antibody TypePrimary Antibodies
NCBI Full Gene Namealdo-keto reductase family 1 member C1
NCBI Gene Aliases20-ALPHA-HSD, DDH1, DD1, HBAB, MBAB, HAKRC, DD1/DD2, C9, DDH, aldo-keto reductase family 1 member C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB, H-37, 2-ALPHA-HSD
Research AreaCancer
Gene NameAKR1C1

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GeneTex

GeneTex, Inc. 2456 Alton Parkway

Irvine, California 92606

United States

Phone: 1-877-GeneTex (436-3839) or 949-553-1900
Fax: 949-309-2888

Company Profile

Website: http://www.genetex.com

(1) Targeting AKR1C1 overcomes lenvatinib resistance in hepatocellular carcinoma through the STAT3-ABC transporters pathwayJournal of Gastrointestinal OncologyApril 30, 2026Yue Zhang, Lu Zheng, An-Qiang Feng, Cheng-Wen Zhao, Xin-Wei Xu, Han Wu, Yang Yu, Feng Gu, Yong-Qiang ChenIL, USA). MRP2 (also known as ABCC2, A5785) was purchased from Selleck (Houston, TX, USA). AKR1C1 (GTX105620) was purchased from GeneTex (Irvine, CA, USA). Secondary antibodies conjugated with HRP were obtained

(2) Age-related downregulation of dihydrotestosterone-inactivating enzymes in human scalp sebaceous glandsInflamm RegenApril 7, 2026Yasuaki Ikuno, Yukie Kande, Akiko Arakawa, Akihiko Yamaguchi, Toshifumi Takahashi, Noriki Fujimoto, Hayato Naka-Kanedaembryonic kidney 293 T (HEK293T) cells overexpressing each AKR1C. The anti-AKR1C1 antibody (GeneTex, GTX105620) recognized AKR1C1/2/3 proteins, whereas the anti-AKR1C4 antibody (Atlas antibodies, HPA044720) selectively

(3) Study of an N6-methyladenosine- and ferroptosis-related prognostic model and the mechanisms underlying the molecular network in neuroblastoma based on multiple datasetsDiscov OncolFebruary 18, 2025Chu J.performed according to previous experimental procedures [24]. Primary antibodies included AKR1C1 (GeneTex, GTX105620, diluted at 1:1000), and β-Actin (Cell Signaling, #4967, diluted at 1:1000) was used to normalize the

(4) Promegestone Prevents Lipopolysaccharide-Induced Cervical Remodeling in Pregnant MiceCellsFebruary 7, 2025Nadeem A, Nadeem L, Lye SJ, Shynlova O.primary antibodies for SRD5A1 (ProteinTech, 26001-1AP, Chicago, IL, USA), 20α-HSD (aka AKR1C1) (GeneTex, GTX105620, Hercules, CA, USA), HABP (Amsbio, AMS.HKD-BC41, Abingdon, UK) proteins, and F4/80, a specific marker

(5) Proteogenomic Landscape of Breast Ductal Carcinoma Reveals Tumor Progression Characteristics and Therapeutic TargetsAdvanced science (Weinheim, Baden-Wurttemberg, Germany)December 1, 2024Xu G, Yu J, Lyu J, Zhan M, Xu J, Huang M, Zhao R, Li Y, Zhu J, Feng J, et al.

(6) A pro-metastatic tRNA fragment drives aldolase A oligomerization to enhance aerobic glycolysis in lung adenocarcinomaCell reportsAugust 27, 2024Wang Q, Song X, Zhang Y, Liang S, Zhang M, Wang H, Feng Y, Li R, Ding H, Chen Y, et al.

(7) Progesterone inactivation in decidual stromal cells: A mechanism for inflammation-induced parturitionProceedings of the National Academy of Sciences of the United States of AmericaJune 18, 2024DeTomaso A, Kim H, Shauh J, Adulla A, Zigo S, Ghoul M, Presicce P, Kallapur SG, Goodman W, Tilburgs T, et al.in antibody diluent (Cell Signaling Technology cat no. 8112L) or rabbit anti-AKR1C1 (GeneTex cat no. GTX105620) each in antibody diluent (Cell Signaling Technology cat no. 8112L). The following day, sections were

(8) NEAT1_1 confers gefitinib resistance in lung adenocarcinoma through promoting AKR1C1-mediated ferroptosis defenceCell death discoveryMarch 12, 2024Zhen S, Jia Y, Zhao Y, Wang J, Zheng B, Liu T, Duan Y, Lv W, Wang J, Xu F, et al.incubation at 4 °C with different dilutions of the primary antibodies, including antibodies to AKR1C1 (GTX105620, GeneTex, Alton Pkwy Irvine, CA, USA), MET (#3127, Cell Signaling Technology, Danvers, MA, USA), GAPDH

(9) Regulation of 20α-Hydroxysteroid Dehydrogenase Expression in Term Pregnant Human Myometrium Ex VivoReproductive sciences (Thousand Oaks, Calif.)January 1, 2024Paul M, Barreda AP, Gregson A, Kahl R, King M, Hussein WM, Walker FR, Smith R, Zakar T, Paul JW.500 mM NaCl, 20 mM Tris, 0.01% Tween-20) overnight at 4 °C. Antibodies against AKR1C1 (GeneTex, cat# GTX105620, rabbit polyclonal) and a β-actin (Abcam, cat# ab8226, mouse monoclonal) were applied at 1∶1,000 dilution.

(10) 20α-Hydroxysteroid Dehydrogenase Expression in the Human Myometrium at Term and Preterm Birth: Relationships to Fetal Sex and Maternal Body Mass IndexReproductive sciences (Thousand Oaks, Calif.)August 1, 2023Paul M, Zakar T, Phung J, Gregson A, Barreda AP, Butler TA, Walker FR, Pennell C, Smith R, Paul JW.(TBS-T; 500 mM NaCl, 20 mM Tris, 0.01% Tween-20) overnight at 4°C. Antibodies against AKR1C1 (cat# GTX105620, GeneTex, rabbit polyclonal; and cat# PA5-84776, ThermoFisher, rabbit polyclonal) and a β-actin (cat#

(11) AKR1C1 promotes non-small cell lung cancer proliferation via crosstalk between HIF-1α and metabolic reprogrammingTranslational oncologyJune 1, 2022Chang LL, Lu PH, Yang W, Hu Y, Zheng L, Zhao Q, Lin NM, Zhang WZ.9710, MAIXIN, Fuzhou, Fujian, China) was applied to the pretreated tumour tissues. AKR1C1 antibody (GTX105620, GeneTex, Irvine, California, USA) was diluted in 1:2000. Images were photographed by an inverted microscope

(12) Pro-inflammatory signals induce 20α-HSD expression in myometrial cells: A key mechanism for local progesterone withdrawalJournal of cellular and molecular medicineJuly 1, 2021Nadeem L, Balendran R, Dorogin A, Mesiano S, Shynlova O, Lye SJ.Antibody,Catalogue #,Dilution,Source 20α‐HSD/AKR1C1,GTX105620,WB ‐ 1:1000 IF ‐ 1:100,GeneTex SMA,M0851,1:100,DAKO ERK2,sc‐154,1:2000,Santa Cruz p‐cFOS,5348,1:500,Cell Signaling

(13) Upregulation of AKR1C1 in mesenchymal stromal cells promotes the survival of acute myeloid leukaemia cellsBritish journal of haematologyMay 1, 2020Jiang Y, Li Y, Cheng J, Ma J, Li Q, Pang T.

(14) Upregulation of lipid metabolism genes in the breast prior to cancer diagnosisNPJ breast cancerJanuary 1, 2020Marino N, German R, Rao X, Simpson E, Liu S, Wan J, Liu Y, Sandusky G, Jacobsen M, Stoval M, et al.washed in distilled water, and counterstained with hematoxylin. Antibodies specific for AKR1C1 (GeneTex, GTX105620, 1:100), HSL (ThermoFisher Scientific, PA5-2638, 1:250), CD36 (Sigma, HPA002018, 1:500), AQP7 (Novus,

(15) The SIRT2-mediated deacetylation of AKR1C1 is required for suppressing its pro-metastasis function in Non-Small Cell Lung CancerTheranosticsJanuary 1, 2020Zhu H, Hu Y, Zeng C, Chang L, Ge F, Wang W, Yan F, Zhao Q, Cao J, Ying M, et al.1139ML500). After blocking, the primary antibodies were used overnight at 4°C as follows: AKR1C1 (GeneTex, GTX105620), SIRT2 (Sigma-Aldrich, S8447).After washed with PBS three times, cells were incubated for 1 h at room

(16) Liquiritin, as a Natural Inhibitor of AKR1C1, Could Interfere With the Progesterone MetabolismFrontiers in physiologyJanuary 1, 2019Zeng C, Zhu D, You J, Dong X, Yang B, Zhu H, He Q.(Zhou et al., 2016). Primary antibodies were as follows: GAPDH (Santa Cruz, sc-25778), AKR1C1 (GeneTex, GTX105620), and GST (Santa Cruz, sc-138). Evaluation of Inhibitors in the Cells HEC-1-B cell line was purchased

(17) AKR1C1 Activates STAT3 to Promote the Metastasis of Non-Small Cell Lung CancerTheranosticsJanuary 1, 2018Zhu H, Chang LL, Yan FJ, Hu Y, Zeng CM, Zhou TY, Yuan T, Ying MD, Cao J, He QJ, et al.LaminB (Santa Cruz, sc-6216), β-Actin (Santa Cruz, sc-1615), HA (Santa Cruz, sc-805), AKR1C1 (GeneTex, GTX105620), flag (Sigma, 7425), GST (Santa Cruz, sc-138). Immunofluorescence Cells were plated at a confluence

(18) AgRP-Expressing Adrenal Chromaffin Cells Are Involved in the Sympathetic Response to FastingEndocrinologyAugust 1, 2017Gupta R, Ma Y, Wang M, Whim MD.

(19) Preferential expression of potential markers for cancer stem cells in large cell neuroendocrine carcinoma of the lung. An FFPE proteomic studyJournal of clinical bioinformaticsSeptember 3, 2011Nomura M, Fukuda T, Fujii K, Kawamura T, Tojo H, Kihara M, Bando Y, Gazdar AF, Tsuboi M, Oshiro H, et al.

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Anti-AKR1C1 antibody

Anti-AKR1C1 antibody

Anti-AKR1C1 antibody

Anti-AKR1C1 antibody from GeneTex

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Anti-AKR1C1 antibody from GeneTex

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