MyBioSource.com's Rabbit anti-human WD repeat-containing protein 5 polyclonal Antibody(WDR5) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, Immunohistochemistry, and Western Blot. The Rabbit anti-human WD repeat-containing protein 5 polyclonal Antibody(WDR5) was generated using WDR5 as the antigen and it reacts with Human.
Description
Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation