MyBioSource.com's HSF1 polyclonal antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, Immunoprecipitation, Super Shift Assay, and Western Blot. The HSF1 polyclonal antibody was generated using HSF1, and Hsf3 as the antigen and it reacts with Human, Mouse, Rat, Non-Human Primate, Rabbit, and Other Mammalian.
Description
HSFs (Heat Shock family of transcription factors), which consists of HSF 1-4, bind to highly conserved Heat shock elements (HSEs) in the promoter regions of heat shock genes, ultimately regulating the expression of Heat shock proteins (Hsps). On exposure to heat shock and other stresses, HSF1 localizes within seconds to discrete nuclear granules and on recovery from stress, HSF1 rapidly dissipates from the stress granules to a diffuse nucleoplasmic distribution