MyBioSource.com's Rabbit anti-human E3 Ribonucleoside-diphosphate reductase subunit M2 B polyclonal Antibody(RRM2B) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, Immunohistochemistry, and Western Blot. The Rabbit anti-human E3 Ribonucleoside-diphosphate reductase subunit M2 B polyclonal Antibody(RRM2B) was generated using RRM2B as the antigen and it reacts with Human.
Description
Plays a pivotal role in cell survival by repairing damaged DNA in a p53/TP53-dependent manner. Supplies deoxyribonucleotides for DNA repair in cells arrested at G1 or G2. Contains an iron-tyrosyl free radical center required for catalysis. Forms an active ribonucleotide reductase (RNR) complex with RRM1 which is expressed both in resting and proliferating cells in response to DNA damage