The Rabbit anti-human Profilin-1 polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to PFN1, and profilin 1. This antibody recognizes Human antigen. The Rabbit anti-human Profilin-1 polyclonal Antibody has been shown to work in the following applications: ELISA, and Western Blot.
Description
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
This protein is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome