MyBioSource.com's Rabbit anti-human Splicing factor 3B subunit 2 polyclonal Antibody(SF3B2) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, and Immunohistochemistry. The Rabbit anti-human Splicing factor 3B subunit 2 polyclonal Antibody(SF3B2) was generated using SF3B2 as the antigen and it reacts with Human.
Description
Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron