HLA-DP/-DR (MHC II) MBS439134 from MyBioSource.com

Product Specs
ItemHLA-DP/-DR (MHC II)
CompanyMyBioSource.com
Price $275.00Supplier Page View Company Product Page
Catalog NumberMBS439134
ReactivityHuman (Hu)
ClonalityMonoclonal
NCBI Gene AliasesHLA-DP, HLA-DP1B, DPB1, HLA-DPB
NCBI Full Gene Namemajor histocompatibility complex, class II, DP beta 1
ApplicationsFCM, IF, IHC-p
ImmunogenReacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DR and DP. Human MHC class II antigens are transmembrane glycoproteins composed of an chain (36kDa) and a chain (27kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six and ten chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles
HostMouse
CloneBra-14
Molecular WeightAntigen: 36kDa (alpha chain); 27kDa (beta chain)
IsotypeIgG3 kappa
TargetHLA-DP/-DR
Format200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml
Conjugate/TagUnconjugated
ConcentrationPurified Ab with BSA and Azide at 200ug/ml
Quantity0.1 mg