The Rabbit anti-human Substance-P receptor polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to tachykinin receptor 1, and Tacr1. This antibody recognizes Human antigen. The Rabbit anti-human Substance-P receptor polyclonal Antibody has been shown to work in the following applications: ELISA, and Immunohistochemistry.
Description
This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.
This gene belongs to a gene family of tachykinin receptors. These tachykinin receptors are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin substance P, also referred to as neurokinin 1. The encoded protein is also involved in the mediation of phosphatidylinositol metabolism of substance P