CD3e (T-Cell Marker) MBS438979 from MyBioSource.com

Product Specs
ItemCD3e (T-Cell Marker)
CompanyMyBioSource.com
Price $275.00Supplier Page View Company Product Page
Catalog NumberMBS438979
Quantity0.1 mg
ApplicationsInduce T cell activation and proliferation, Flow Cytometry (FC/FACS), Immunofluorescence (IF)
ConcentrationPurified Ab with BSA and Azide at 200ug/ml
Conjugate/TagUnconjugated
Format200ug/ml of Ab purified from rabbit anti-serum by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0mg/ml
ReactivityHuman, Monkey
TargetCD3e
IsotypeIgG2a kappa
Molecular WeightAntigen: 20kDa
CloneCRIS-7
HostMouse
ImmunogenRecognizes the -chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms
NCBI Full Gene NameCD3e molecule, epsilon (CD3-TCR complex)
NCBI Gene AliasesIMD18, T3E, TCRE
ClonalityMonoclonal