The Rabbit anti-human Ciliary neurotrophic factor polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Ciliary Neurotrophic Factor, and CNTF. This antibody recognizes Human antigen. The Rabbit anti-human Ciliary neurotrophic factor polyclonal Antibody has been shown to work in the following applications: ELISA, and Immunohistochemistry.
Description
CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
This protein is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of ZFP91 and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse