MyBioSource.com's CNG-1beta Polyclonal Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: EIA, Immunoassay, ELISA, and Western Blot.
Description
In humans, the rod photoreceptor cGMP-gated cation channel helpsregulate ion flow into the rod photoreceptor outer segment in response tolight-induced alteration of the levels of intracellular cGMP. This channelconsists of two subunits, alpha and beta, with the protein encoded by thisgene representing the beta subunit. Defects in this gene are a cause ofcause of retinitis pigmentosa type 45. Three transcript variants encodingdifferent isoforms have been found for this gene.CNGB1 (CyclicNucleotide Gated Channel Beta 1) is a Protein Coding gene. Diseasesassociated with CNGB1 include Retinitis Pigmentosa 45 andCngb1-Related Retinitis Pigmentosa. Among its related pathways arePhototransduction and Metabolism of fat-soluble vitamins. GOannotations related to this gene include voltage-gated potassium channelactivity and cGMP binding. An important paralog of this gene is CNGB3