MyBioSource.com's IGF2R Polyclonal Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: EIA, Immunoassay, ELISA, and Western Blot. The IGF2R Polyclonal Antibody was generated using IGF2R as the antigen and it reacts with Human.
Description
This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located ondifferent segments of the receptor. This receptor functions in theintracellular trafficking of lysosomal enzymes, the activation oftransforming growth factor beta, and the degradation of insulin-likegrowth factor 2. While the related mouse gene shows exclusive expressionfrom the maternal allele, imprinting of the human gene appears to bepolymorphic, with only a minority of individuals showing expressionfrom the maternal allele