The SAP97 monoclonal antibody (RPI 197.4) from MyBioSource.com is a Mouse Monoclonal antibody to DLG1. This antibody recognizes Human, Mouse, Rat, and Canine antigen. The SAP97 monoclonal antibody (RPI 197.4) has been shown to work in the following applications: Electron Microscopy, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, and Western Blot.
Description
Synapse-associated proteins SAP97 and SAP102 display extensive sequence homology to the PSD 95 family of proteins that facilitate ion channel clustering at synaptic terminals. In addition to the CNS, SAP97 is also detected at the basal lateral membrane between a variety of epithelial cells. SAP102 associates with NMDA receptors through the C-terminal NR2B subunit of the receptor. The N-terminal SAP97 PDZ domain mediates its interaction with the synaptic ras-GTPase activating protein SynGAP