TGF-beta (Transforming Growth Factor beta) MBS438778 from MyBioSource.com

Product Specs
ItemTGF-beta (Transforming Growth Factor beta)
CompanyMyBioSource.com
Price $275.00Supplier Page View Company Product Page
Catalog NumberMBS438778
Quantity0.1 mg
ApplicationsCytokine Neutralization, Functional Assay
ConcentrationPurified Ab with BSA and Azide at 200ug/ml
Conjugate/TagUnconjugated
Format200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml
ReactivityHuman, Monkey, Cow, Dog, Mouse, Rat, Hamster
TargetTGF-beta
IsotypeIgG1 kappa
Molecular WeightAntigen: 13kDa
Clone1D11.16.8
HostMouse
ImmunogenThis MAb recognizes TGF beta 1, 2 and 3. Three TGFbs have been identified in mammals. TGFb1, TGFb2 and TGFb3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGFb requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGFb3 protein has approximately 80% identity to the mature region of both TGFb1 and TGFb2. However, the NH2 terminals or precursor regions of their molecules share only 27% sequence identity. TGFb's inhibit the growth of epithelial cells and stimulate the growth of mesenchymal cells
NCBI Full Gene Nametransforming growth factor, beta 1
NCBI Gene AliasesTGFbeta, TGFB, LAP, CED, DPD1
ClonalityMonoclonal