TOX3 / TNRC9 Antibody MBS439154 from MyBioSource.com

Product Specs
ItemTOX3 / TNRC9 Antibody
CompanyMyBioSource.com
Price $275.00Supplier Page View Company Product Page
Catalog NumberMBS439154
ReactivityHuman (Hu)
ClonalityMonoclonal
NCBI Gene AliasesTNRC9, CAGF9
NCBI Full Gene NameTOX high mobility group box family member 3
ApplicationsWB, FCM, IF
ImmunogenIt recognizes a 63kDa protein, which is identified as TOX3. It contains a high mobility group (HMG)-box, which regulates Ca2+-dependent transcription in neurons through interaction with the cAMP-response-element-binding protein (CREB). TOX3 appears to be associated with breast cancer susceptibility and is expressed downstream of a cytoprotective cascade together with CITED1, a transcriptional regulator that does not bind directly to DNA. TOX3 is predominantly expressed in the brain and forms homodimers. TOX3 overexpression protects neuronal cells from cell death caused by endoplasmic reticulum stress or BAX overexpression through the induction of anti-apoptotic transcripts and repression of pro-apoptotic transcripts
HostMouse
CloneTOX3/1124
Molecular WeightAntigen: 63kDa
IsotypeIgG1 kappa
TargetTOX3 / TNRC9
Format200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 1mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml
Conjugate/TagUnconjugated
ConcentrationPurified Ab with BSA and Azide at 200ug/ml
Quantity0.1 mg