CD54 / ICAM-1 Antibody MBS439766 from MyBioSource.com

Product Specs
ItemCD54 / ICAM-1 Antibody
CompanyMyBioSource.com
Price $275.00Supplier Page View Company Product Page
Catalog NumberMBS439766
Quantity0.1 mg
ApplicationsFunctional Studies, Flow Cytometry (FC/FACS), Immunofluorescence (IF)
ConcentrationPurified Ab with BSA and Azide at 200ug/ml
Conjugate/TagUnconjugated
Format200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml
ReactivityHuman
TargetCD54 / ICAM-1
IsotypeIgG2a kappa
Molecular WeightAntigen: 85-115kDa
CloneF4-31C2
HostMouse
ImmunogenRecognizes an 85-115kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1). It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. ICAM-1 may also be related to progression and metastasis of tumors
NCBI Full Gene Nameintercellular adhesion molecule 1
NCBI Gene AliasesBB2, CD54, P3.58
ClonalityMonoclonal