MyBioSource.com's Rabbit anti-human Ras-related protein Rab-5A polyclonal Antibody(RAB5A) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, Immunohistochemistry, and Western Blot. The Rabbit anti-human Ras-related protein Rab-5A polyclonal Antibody(RAB5A) was generated using RAB5A as the antigen and it reacts with Human, and Mouse.
Description
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulation of filopodia extension