NMDAR2B Antibody

Product Specs
ItemNMDAR2B Antibody - C-terminus - Azide Free
CompanyNovus Biologicals, a Bio-Techne Brand
Price $399.00Supplier Page View Company Product Page
Catalog NumberNB300-106-100ul
Quantity100 ul
ApplicationsIF/IHC,Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence
Conjugate/TagUnconjugated
Format10mM HEPES (pH 7.5), 0.15M NaCl, 0.1 mg/ml BSA and 50% Glycerol
ReactivityHuman,Mouse,Rat
PurityAntigen Affinity-purified
TargetNMDAR2B
HostRabbit
Molecular Weight180 kDa
IsotypeIgG
Antibody TypePrimary Antibodies
ImmunogenFusion protein from the C-terminal region of the NR2B subunit. Accession # Q00960
ClonalityPolyclonal
Research AreaAutophagy, Neurodegeneration, Neuroendocrinology, Neuronal Cell Markers, Neuroscience
NCBI Full Gene Nameglutamate ionotropic receptor NMDA type subunit 2B
NCBI Gene AliasesMRD6, EIEE27, NR2B, DEE27, hNR3, GluN2B, NR3, NMDAR2B
StorageStore at -20C. Avoid freeze-thaw cycles

Specifications/Features

Available conjugates: Unconjugated

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Novus Biologicals, a Bio-Techne Brand

United States: 10771 E Easter Ave

Centennial, Colorado 80112

United States

Phone:
303-730-1950
888-506-6887

Email: novus@novusbio.com

Company Profile

Website: https://www.novusbio.com

(1) A sensory and motor neuropathy caused by a genetic variant of NAMPTScience advancesSeptember 26, 2025Zhang Z, Pilch J, Lundt S, Zhang N, Chang Y, Singer T, Śladowski D, Hu XL, Zheng L, Ge WP, et al.anti-NMDAR2A (1:1000, NB300-105, Novus Biologicals; RRID:AB_10001400), rabbit anti-NMDAR2B (1:1000, NB300-106, Novus Biologicals; RRID:AB_10000537), mouse anti-GluA1 (1:1000, NBP2-22399, Novus Biologicals), rabbit

(2) Reactive Astrocytes Release GDNF to Promote Brain Recovery and Neuronal Survival Following Ischemic StrokeNeurochemical researchMarch 14, 2025Zhang Z, Zhang N, Ding S.anti-NMDAR2A polyclonal antibody (1:500, NB300-105, Novus), a rabbit anti-NMDAR2B polyclonal antibody (1:500, NB300-106, Novus), a mouse anti-β-actin monoclonal antibody (1:5000, Cat. No. SC-47778, Santa Cruz Biotechnology). Immunochemical

(3) TwinF interface inhibitor FP802 stops loss of motor neurons and mitigates disease progression in a mouse model of ALSCell Reports MedicineFebruary 20, 2024Jing Yan, Yu Meng Wang, Andrea Hellwig, Hilmar Badingpolyclonal anti-GluN2A,Millipore,Cat#AB1555;RRID: AB_2112325 Rabbit polyclonal anti-GluN2B,Novus,Cat#NB300-106;RRID: AB_10000537 Rabbit polyclonal anti-Myt1L,"Dr. Moritz Mall, DKFZ, Heidelberg",N/A Mouse monoclonal

(4) The Golgi-Associated PDZ Domain Protein Gopc/PIST Is Required for Synaptic Targeting of mGluR5Molecular neurobiologyNovember 1, 2021Klüssendorf M, Song I, Schau L, Morellini F, Dityatev A, Koliwer J, Kreienkamp HJ.powder/TBS-T,Novus Biologicals(NB300-105) GluN2B,Rabbit,WB 1:1000,5% milk powder/TBS-T,Novus Biologicals(NB300-106) Gopc,Rabbit,WB 1:1000,5% milk powder/TBS-T,Sigma-Aldrich(HPA024018) Gopc,Guinea pig,WB 1:1000IF 1:1000,5%

(5) Imbalanced post- and extrasynaptic SHANK2A functions during development affect social behavior in SHANK2-mediated neuropsychiatric disordersMolecular psychiatryNovember 1, 2021Eltokhi A, Gonzalez-Lozano MA, Oettl LL, Rozov A, Pitzer C, Röth R, Berkel S, Hüser M, Harten A, Kelsch W, et al.

(6) Effects of Nrf1 in Hypothalamic Paraventricular Nucleus on Regulating the Blood Pressure During HypertensionFrontiers in neuroscienceJanuary 1, 2021Yu XJ, Xiao T, Liu XJ, Li Y, Qi J, Zhang N, Fu LY, Liu KL, Li Y, Kang YM.(12482-1-AP, Proteintech), GluN1 (A7677, ABclonal), GluN2A (NB300-105, Novus Biologicals), GluN2B (NB300-106, Novus Biologicals). They were purchased from Santa Cruz Biotechnology. After washing with wash buffer

(7) GLAST-CreER^T2 mediated deletion of GDNF increases brain damage and exacerbates long-term stroke outcomes after focal ischemic stroke in mouse modelGliaNovember 1, 2020Zhang N, Zhang Z, He R, Li H, Ding S.anti-NMDAR2A (1:1000; NB300-105, Novus Biologicals, LLC. RRID:AB_10001400), rabbit anti-NMDAR2B (1:1000; NB300-106, Novus Biologicals, LLC. RRID:AB_10000537), mouse anti-GluA1 (1:1000; NBP2-22399, Novus Biologicals,

(8) Targeting of δ-catenin to postsynaptic sites through interaction with the Shank3 N-terminusMolecular autismOctober 28, 2020Hassani Nia F, Woike D, Martens V, Klüssendorf M, Hönck HH, Harder S, Kreienkamp HJ.rabbit anti-NMDAR2A (Novus Biologicals NB300-105; WB 1:1000); rabbit anti-NMDAR2B (Novus Biologicals NB300-106; WB 1:1000) HRP-labeled goat secondary antibodies were from Jackson ImmunoResearch and used for WB at

(9) It Is All in the Right Amygdala: Increased Synaptic Plasticity and Perineuronal Nets in Male, But Not Female, Juvenile Rat Pups after Exposure to Early-Life StressThe Journal of neuroscience : the official journal of the Society for NeuroscienceOctober 21, 2020Guadagno A, Verlezza S, Long H, Wong TP, Walker CD.GluN1 (G8913, Sigma Millipore, 1:1000), GluN2A (#4205, Cell Signaling Technology, 1:1000), GluN2B (NB300-106, Novus Biologicals, 1:1000), GluA1 (AB1504, Millipore, 1:500), GluA2 (MAB397, 1:1000), and actin (A2066,

(10) VEGFD Protects Retinal Ganglion Cells and, consequently, Capillaries against Excitotoxic InjuryMolecular therapy. Methods & clinical developmentJune 12, 2020Schlüter A, Aksan B, Diem R, Fairless R, Mauceri D.rabbit-GluN2A (1:500 in 5% milk; AB1555, Merck Millipore), rabbit anti-GluN2B (1:1,000 in 5% milk; NB300-106, Novus Biologicals, Centennial, CO, USA), rabbit anti-GluN2C (1:1,000 in 5% milk; PAB9705, Abnova, Taiwan,

(11) The green tea polyphenol epigallocatechin-3-gallate (EGCG) restores CDKL5-dependent synaptic defects in vitro and in vivoNeurobiology of diseaseMay 1, 2020Trovò L, Fuchs C, De Rosa R, Barbiero I, Tramarin M, Ciani E, Rusconi L, Kilstrup-Nielsen C.ab11267; Abcam rabbit, ab32454), anti-NR2A (Merck Millipore, 07-632), anti-NR2B (Novus Biologicals, NB300-106), anti-PSD95 (Thermo Fischer Scientific, MA1045), anti-phospho-Tau-T212 (Invitrogen, 44-740G), anti-Tau

(12) Effects of chronic NMDA-NR2b inhibition in the median eminence of the reproductive senescent female ratJournal of neuroendocrinologyOctober 1, 2013Kermath BA, Riha PD, Sajjad A, Gore AC.(NHS) and 2% bovine serum albumin. Next, sections were incubated with 1) rabbit anti-NR2b [1:1000, NB300-106, Novus Biologicals, Littleton, CO; (20,21)] and the mouse monoclonal GnRH [1:1000, Hu11b, kindly provided

(13) Dextromethorphan attenuated the higher vulnerability to inflammatory thermal hyperalgesia caused by prenatal morphine exposure in rat offspringJournal of biomedical scienceAugust 23, 2011Tao PL, Chen CF, Huang EY.

(14) Estradiol potentiation of NR2B-dependent EPSCs is not due to changes in NR2B protein expression or phosphorylationHippocampusApril 1, 2011Snyder MA, Cooke BM, Woolley CS.

(15) Modulation of synaptic plasticity by stress hormone associates with plastic alteration of synaptic NMDA receptor in the adult hippocampusPloS oneJanuary 1, 2011Tse YC, Bagot RC, Hutter JA, Wong AS, Wong TP.

(16) Age- and hormone-regulation of N-methyl-D-aspartate receptor subunit NR2b in the anteroventral periventricular nucleus of the female rat: implications for reproductive senescenceJournal of neuroendocrinologyMay 1, 2009Maffucci JA, Noel ML, Gillette R, Wu D, Gore AC.

(17) Direct-current electrical field guides neuronal stem/progenitor cell migrationStem CellsAugust 1, 2008Li L, El-Hayek YH, Liu B, Chen Y, Gomez E, Wu X, Ning K, Li L, Chang N, Zhang L, et al.

(18) Caveolin-1 expression is essential for N-methyl-D-aspartate receptor-mediated Src and extracellular signal-regulated kinase 1/2 activation and protection of primary neurons from ischemic cell deathFASEB journal : official publication of the Federation of American Societies for Experimental BiologyMarch 1, 2008Head BP, Patel HH, Tsutsumi YM, Hu Y, Mejia T, Mora RC, Insel PA, Roth DM, Drummond JC, Patel PM.

(19) alpha-Isoform of calcium-calmodulin-dependent protein kinase II and postsynaptic density protein 95 differentially regulate synaptic expression of NR2A- and NR2B-containing N-methyl-d-aspartate receptors in hippocampusNeuroscienceJanuary 2, 2008Park CS, Elgersma Y, Grant SG, Morrison JH.kDa band. Polyclonal anti-NMDA receptor 2B antibodies (Novus Biologicals, Littleton, CO, catalog # NB300-106) were raised in rabbits to a fusion Neuroscience. Author manuscript; available in PMC 2009 January 2. Park

(20) Decrease in N-methyl-D-aspartic acid receptor-NR2B subunit levels by intrathecal short-hairpin RNA blocks group I metabotropic glutamate receptor-mediated hyperalgesiaThe Journal of pharmacology and experimental therapeuticsJuly 1, 2007Gabra BH, Kessler FK, Ritter JK, Dewey WL, Smith FL.

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