PI3 Kinase p110gamma (D55D5) Rabbit mAb 5405S from Cell Signaling Technology

Product Specs
ItemPI3 Kinase p110gamma (D55D5) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number5405S
Quantity100 µl
ApplicationsW, IP
ReactivityH, M
TargetPI3K p110 gamma
HostRabbit
NCBI Gene AliasesIMD97, PI3CG, PI3K, PI3Kgamma, PIK3, p110gamma, p120-PI3K
ClonalityMonoclonal
NCBI Full Gene Namephosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
Research AreaPI3K / Akt Signaling
IsotypeIgG
CloneD55D5
Molecular Weight110

Add to Compare List

Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Plagl1 regulates the retinal progenitor cell to Müller glial cell transitionPLoS GenetMarch 18, 2026Yacine Touahri, Alissa Pak, Luke Ajay David, Joseph Hanna, Hedy Liu, Yucheng Xiao, Lauren Belfiore, Yaroslav Ilnytskyy, Edwin van Oosten, Nobuhiko Tachibana, et al.#019–19741), rat anti-mKi67 (1/250, Invitrogen 14-5698-82), rabbit anti-M-opsin (1/250, Millipore #5405), rabbit anti-Pax6 (1/500, Convance #PRB-278P), rabbit anti-pERK (Map kinase p44/42 phospho-Thr202/Tyr204)

(2) SH3 domains selectively activate the PI3 kinase through non-conventional tertiary contactsCommunications BiologyJanuary 19, 2026Safia S. Aljedani, Anandsukeerthi Sandholu, Abdullah Aldehaiman, Siba Alharbi, Victor C. Y. Mak, Haiyan Wu, Panpan Wang, Afaque A. Momin, Upendra Singh, Adrien Lugari, et al.anti-p110β antibody (CST#3011; 1:1000), anti-p110δ antibody (CST#34050; 1:1000), anti-p110γ antibody (CST#5405; 1:1000), anti-p85α antibody (Santa Cruz sc-71892; 1:200), anti-p85β (Abcam, Cambridge, United Kingdom;

(3) Impaired macroautophagy confers substantial risk for intellectual disability in children with autism spectrum disordersMolecular PsychiatryDecember 11, 2025Ahrom Ham, Audrey Yuen Chang, Hongyu Li, Jennifer M. Bain, James E. Goldman, David Sulzer, Jeremy Veenstra-VanderWeele, Guomei TangProteintech, # 20986–1-AP), ATG9A (Abcam, #ab108338, anti-rabbit), PI3Kγ (Cell Signaling Technology, #5405, anti-rabbit), ACTIN (Sigma, #A5411, anti-mouse), LAMP1 (Abcam, #ab24170, anti-rabbit). Secondary antibodies

(4) Neutrophil extracellular trap-borne C3-driven endothelial dysfunction in Klebsiella pneumoniae liver abscessVirulenceOctober 28, 2025Hongguang Wang, Lulu Chen, Chuanzhuo Wang, Zhihui ChangUSA), anti-PI3 Kinase p110δ (Cat: 34,050, Cell Signaling Technology, USA), anti-PI3 Kinase p110γ (Cat: 5405, Cell Signaling Technology, USA), anti-PI3 Kinase p110β (Cat: 3011, Cell Signaling Technology, USA),

(5) TOPK Drives IL19-Mediated Crosstalk Between Cancer Cells and Fibroblasts to Promote Solar UV-Induced Skin Damage and CarcinogenesisCancers (Basel)June 20, 2025Asad U. Khan, Qiushi Wang, Eunmiri Roh, Sally E. Dickinson, Georg T. Wondrak, Clara Curiel-Lewandowski, Ann M. Bode, Tianshun ZhangUSA). Antibodies for total protein detection were also purchased from CST, including PI3K p110γ (D55D5, 5405s), AKT (C9272s), ERK p44/42 MAPK (9102), JNK (9252), p38 MAPK (D13E1, 8690), PKA C-α (4782), PKCι/C83H11

(6) A common variant in PIK3CG gene associated with the prognosis of heart failureJournal of Cellular and Molecular MedicineSeptember 8, 2024Dong Hu, Lei Xiao, Shiyang LiGermany). 3 MATERIALS Anti‐PIK3CG and anti‐ACTB antibody were purchased from Cell Signalling Technology (#5405) and ABclonal Technology (AC026), respectively. The sequence of siRNAs targeting PIK3CG gene was as

(7) Oral administration of IPI549 protects mice from neuropathology and an overwhelming inflammatory response during experimental cerebral malariaInternational Journal for Parasitology: Drugs and Drug ResistanceAugust 1, 2024Zhuoru Jin, Wei Pang, Yan Zhao, Hui Min, Shijie Yao, Zhifang Bian, Yixin Wen, Chuanyang Peng, Yaming Cao, Li Zheng(Thermo Scientific, USA, # 37,525). The membrane was incubated overnight at 4 °C with anti-P110γ (#5405S), anti-AKT (#9272S), anti-NF-κB (#8242S), or anti-mTOR (#2983S) (1:1000 dilution) antibodies (Cell Signaling Technology

(8) Degradation‐Based Protein Profiling: A Case Study of CelastrolAdvanced ScienceJuly 1, 2024Zhihao Ni, Yi Shi, Qianlong Liu, Liguo Wang, Xiuyun Sun, Yu Rao(Abcam, ab124957), anti‐PI3K p110α (CST, 4249S), anti‐PI3K p110β (CST, 3011S), anti‐PI3K p110γ (CST, 5405S), anti‐CHK1 (Abcam, ab32531), anti‐Flag (Abmart, M20008), anti‐NEK7 (Abcam, ab133514), anti‐OGA (Abcam,

(9) A prospective study of HER3 expression pre and post neoadjuvant therapy of different breast cancer subtypes: implications for HER3 imaging therapy guidanceBreast Cancer ResearchJune 29, 2024Nicoleta Sinevici, Christine E. Edmonds, Brian N. Dontchos, Gary Wang, Constance D. Lehman, Steven Isakoff, Umar Mahmood(4791, Cell Signaling), anti-AKT (2920, Cell Signaling) anti-pAKT (4060S, Cell Signaling), anti-Pi3K (5405, Cell Signaling), anti-p-Pi3K (4228, Cell Signaling), anti-ERK (4695, Cell Signaling), anti-pERK (4377,

(10) Therapeutic potential of anti-PIK3CG treatment for multiple myeloma via inhibiting c-Myc pathwayHeliyonDecember 6, 2023Xiaotang Di, Yiwen Pan, Jinhua Yan, Jing Liu, Doudou Wen, Hao Jiang, Shubing ZhangProteintech, No. 50599-2-Ig), Bcl-2 (1:1000; Proteintech, No. 12789-1-AP), PIK3CG (1:1000; CST, No.5405), AKT (1:1000; CST, No.4691), p-AKT (1:1000; CST, No.4060), RELA (1:1000; ABclonal, No.A16271), p-RELA(1:1000;

(11) The potential effect and mechanism of Saikosaponin A against gastric cancerBMC Complementary Medicine and TherapiesAugust 22, 2023Chao Wang, Ruijuan Zhang, Xu Chen, Mengyun Yuan, Jian Wu, Qingmin Sun, Chunrun Miao, Yali Jingdimethyl sulfoxide (DMSO) at a concentration of 50 mg/ml. Antibodies against p-PI3K (No. 4228S), PI3K (No. 5405S), p-AKT (No. 2965S), AKT (No. 4691S), p-mTOR (No. 2971S), mTOR (No. 2972S), Cleaved Caspase-3 (No. 9554

(12) The potential therapeutic regimen for overcoming resistance to osimertinib due to rare mutations in NSCLCiScienceJuly 21, 2023Rui Han, Caiyu Lin, Chong Zhang, Jun Kang, Conghua Lu, Yiming Zhang, Yubo Wang, Chen Hu, Yong HeThe following primary antibodies were used: Antibodies against PI3K (P110α) (#4255S), PI3K (P110γ) (#5405S), Bim (#2933S), Akt (#9272S), phospho (Ser473)-Akt (#4060S), mTOR (#2983), phospho(Ser2448)-mTOR (#5536),

(13) Combination Treatment Targeting mTOR and MAPK Pathways Has Synergistic Activity in Multiple MyelomaCancersApril 19, 2023Sun K, Jin L, Karolová J, Vorwerk J, Hailfinger S, Opalka B, Zapukhlyak M, Lenz G, Khandanpour C.Cell Signaling Technology (Danvers, MA, USA): PI3Kα (Cat#.4249S), PI3Kβ (Cat.#3011S), PI3K γ (Cat.#5405S), panAKT (Cat.#9272), p-AKT S473 (Cat.#4058), p-AKT T308 (Cat.#2965), p-p70S6K (Cat.#9234), p-S6 (Cat.#2211),

(14) Patulin Alters Insulin Signaling and Metabolic Flexibility in HepG2 and HEK293 CellsToxins (Basel)March 27, 2023Yashodani Pillay, Savania Nagiah, Anil Chuturgoonp44/42 MAPK (ERK1/2) (CST#9102); phosphor-p44/42 MAPK (ERK1/2) (Thr202/Try204) (CST#9106); PI3K (CST#5405); phosphor-ser473 Akt (CST#9271); Akt (CST#9272); PDK-1 (ab110025); phosphor-PDH (E1α) (ab92696); PDH

(15) Stellettin B Sensitizes Glioblastoma to DNA‐Damaging Treatments by Suppressing PI3K‐Mediated Homologous Recombination RepairAdvanced ScienceJanuary 1, 2023Xin Peng, Shaolu Zhang, Yingying Wang, Zhicheng Zhou, Zixiang Yu, Zhenxing Zhong, Liang Zhang, Zhe‐Sheng Chen, Francois X. Claret, Moshe Elkabets, et al.(Cell Signaling Technology, 4249), PI3Kβ (Cell Signaling Technology, 3011), PI3Kγ (Cell Signaling Technology, 5405), PI3Kδ (Cell Signaling Technology, 34050), phospho‐Akt (Thr308, Cell Signaling Technology, 13038),

(16) Neddylation-dependent protein degradation is a nexus between synaptic insulin resistance, neuroinflammation and Alzheimer’s diseaseTranslational NeurodegenerationDecember 1, 2022Alessandro Dario Confettura et al.insoluble material. The supernatant was incubated with 2 µg of rabbit polyclonal anti-PI3Kγ antibody (#5405; Cell Signaling Technology, Frankfurt, Germany) with gentle rotation for 1 h at 4 °C. Secondary antibody-bound

(17) Inhibition of Phosphoinositide 3-Kinase Gamma Protects Endothelial Cells via the Akt Signaling Pathway in Sepsis-Induced Acute Kidney InjuryKidney and Blood Pressure ResearchSeptember 21, 2022Han Li, Jun-Xian Xu, Tiao-Chun Cheng, Li-Jun Tian, Jin-Feng Lin, Xi Luo, Zhao-Lian Bian, Xu-Dong Hanat 100 V for 90 min. After blocking with 5% nonfat milk, membranes were incubated with anti-PI3Kγ (5405, 1:1,000; Cell Signaling Technology), pAkt (4060, 1:2,000, Cell Signaling Technology), Akt (4691, 1:1,000;

(18) Hydrophobic Bile Salts Induce Pro-Fibrogenic Proliferation of Hepatic Stellate Cells through PI3K p110 Alpha SignalingCellsJuly 29, 2022Sebastian Zimny, Dennis Koob, Jingguo Li, Ralf Wimmer, Tobias Schiergens, Jutta Nagel, Florian Paul Reiter, Gerald Denk, Simon HohenesterCatalog ID: #3011, Cell signaling, Danvers, MA, USA), PI3K p110γ (1:1000 in 3% albumin; Catalog ID: #5405, Cell signaling, Danvers, MA, USA), PI3K p110δ (1:1000 in 3% albumin; Catalog ID: #34050, Cell signaling,

(19) P2RY2-AKT activation is a therapeutically actionable consequence of XPO1 inhibition in acute myeloid leukemiaNature CancerJune 6, 2022Kevin H. Lin, Justine C. Rutter, Abigail Xie, Shane T. Killarney, Camille Vaganay, Chaima Benaksas, Frank Ling, Gaetano Sodaro, Paul-Arthur Meslin, Christopher F. Bassil, et al.1:1000 in 5% BSA), cleaved-Caspase3 D175 (CST #9661 diluted 1:500 in 5% BSA), p110-g (D55D5) (CST #5405 diluted 1:1000 in 5% BSA), p110α (C73F8) (CST #4249 diluted 1:1000 in 5% BSA), p110β (C33D4) (CST #3011

(20) Nanoparticle-enhanced radiotherapy synergizes with PD-L1 blockade to limit post-surgical cancer recurrence and metastasisNature communicationsMay 20, 2022Guan X, Sun L, Shen Y, Jin F, Bo X, Zhu C, Han X, Li X, Chen Y, Xu H, et al.the protein was incubated with 1:1000 diluted anti-PI3K p110 gamma antibody (CST, D55D5, Catalog No.5405 T) and anti-GADPH antibody (CST, D16H11, Catalog No.5174 T) at 4°C overnight followed by incubation

Be the First to Write a Review!

PI3 Kinase p110gamma (D55D5) Rabbit mAb

PI3 Kinase p110gamma (D55D5) Rabbit mAb from Cell Signaling Technology

Description

Cell Signaling Technology

Citations (51)

Reviews

PI3 Kinase p110gamma (D55D5) Rabbit mAb from Cell Signaling Technology

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map