Desmin (D93F5) XP ® Rabbit mAb 5332S from Cell Signaling Technology

Product Specs
ItemDesmin (D93F5) XP ® Rabbit mAb
CompanyCell Signaling Technology
Price $371.00 Inquire
Catalog Number5332S
Quantity100 µl
ApplicationsW, IF-F, IF-IC
ReactivityH, M, R
TargetDesmin
HostRabbit
NCBI Gene AliasesCDCD3, CSM1, CSM2, LGMD1D, LGMD1E, LGMD2R
ClonalityMonoclonal
NCBI Full Gene Namedesmin
Research AreaCytoskeletal Signaling
IsotypeIgG
CloneD93F5
Molecular Weight53

Questions and Answers

Can this antibody be used to study desmin expression in mouse models?

Yes, the Desmin (D93F5) XP® Rabbit mAb has been shown to work effectively in mouse models, as evidenced by its use in various studies, including those investigating skeletal muscle responses to chemotherapy agents like irinotecan and 5-fluorouracil, where desmin levels were assessed using this antibody (, ).

Is this antibody suitable for immunofluorescence applications?

The Desmin (D93F5) XP® Rabbit mAb has been utilized in immunofluorescence assays, as indicated in multiple studies where it was employed to visualize desmin in various tissue types, including skeletal muscle and liver tissues (, ).

What is the molecular weight of the protein detected by this antibody?

The Desmin (D93F5) XP® Rabbit mAb detects desmin, which has a molecular weight of approximately 53 kDa. This information is relevant for researchers conducting Western blot analyses to confirm the presence of desmin in their samples (, ).

Are there any specific conditions or treatments where this antibody has been particularly useful?

This antibody has been particularly useful in studies examining the effects of chemotherapy on skeletal muscle, where it was used to assess changes in desmin expression in response to treatments like irinotecan and 5-fluorouracil, highlighting its role in understanding muscle pathology in cancer contexts (, ).

Cell Signaling Technology

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Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Ex-vivo culture of human hypertrophic cardiomyopathy hearts: Functional and metabolic changes during long-term cultureiScienceApril 17, 2026Ali Nassar, Vincent A.J. Warnaar, Inez Duursma, Bauke V. Schomakers, Chahida Chaami, Julien Ochala, Michel van Weeghel, Riekelt H. Houtkooper, Michelle Michels, Andreas Dendorfer, et al.tubulin,Abcam ab48389,AB_869990 Acetylated tubulin,Sigma Aldrich T7451,AB_609894 Desmin,Cell signaling #5332,AB_1903947 cMyBP-C,Santa Cruz SC-137180,AB_2017317 cTnI,Cell Signaling,4002S MHC,Produced in-house,N/A AKT,Cell signaling

(2) Erk3 deletion drives oxidative adaptations in skeletal muscleMolecular MetabolismFebruary 24, 2026Angel Loza-Valdes, Carlos Acosta-Gallo, Toufic Kassouf, Andrei Belykh, Małgorzata Stelmach, Dominika Malińska, Katia El Ghoz, Rabih El-Merahbi, Filip Dziaczkowski, Katarzyna Kolczyńska-Matysiak, et al.(Cell Signaling, 8174S), α-GAPDH (Sigma, G9545), α-MYHC (Bio-Techne, MAB4470), α-desmin (Cell Signaling, 5332T), α-vinculin (Cell Signaling, 13901S), α-MYH4 (DSHB, BF–F3), α-MYH7 (DSHB, BA-D5), α-MYH2, α-(DSHB,

(3) Mafu Yishen Formula ameliorates membranous nephropathy by promotion of regulatory T cell differentiation: a multi-omics studyChinese MedicineJanuary 6, 2026Qihan Zhao, Haoran Dai, Naiqian Zhang, Shuxian Huang, Xiaoyu Cui, Yanyu Cui, Hanxue Jiang, Wu Liu, Yangzi Chen, Yalin Zheng, et al.as needed: rabbit anti-Synaptopodin antibody (Abcam, #ab259976), rabbit anti-Desmin antibody (CST, #5332), rabbit anti-Bcl-6 antibody (BIOSS, #bs-2734R), AF488-labeled goat anti-rat IgG (Abcam, #ab150157),

(4) Nidogen 1-enriched extracellular vesicles promote liver metastasis by inducing EMT and activating stellate cellsiScienceDecember 19, 2025Haipeng Chen, Hengchang Liu, Lin Wang, Jialiang Liu, Tianli Chen, You Zuo, Hanqing Hu, Xishan Wang, Guiyu Wang,Cell Signaling Technology,Cat. No.97585 IL11,R&D Systems,Cat. No.MAB218-SP Desmin,Cell Signaling Technology,Cat. No.5332T Anti-rabbit IgG,Cell Signaling Technology,Cat. No. 7074P2 Anti-mouse IgG,Cell Signaling Technology,Cat.

(5) VGLL2 and TEAD1 fusion proteins identified in human sarcoma drive YAP/TAZ-independent tumorigenesis by engaging EP300ElifeMay 8, 2025Susu Guo, Xiaodi Hu, Jennifer L Cotton, Lifang Ma, Qi Li, Jiangtao Cui, Yongjie Wang, Ritesh P Thakare, Zhipeng Tao, Y Tony Ip, et al.dilutions used in the studies: Ki67 (cat. 12202, 1:500, Cell Signaling Technology) and Desmin (cat. 5332, 1:100, Cell Signaling Technology). Statistics and reproducibility Statistical analyses were performed

(6) The MFN2 Q367H variant reveals a novel pathomechanism connected to mtDNA-mediated inflammationLife Sci AllianceApril 2, 2025Mashiat Zaman, Govinda Sharma, Walaa Almutawa, Tyler Gb Soule, Rasha Sabouny, Matt Joel, Armaan Mohan, Cole Chute, Jeffrey T Joseph, Gerald Pfeffer, et al.Conversion to myoblasts was confirmed by visualization of desmin using desmin (D93F5) XP rabbit mAb (cat. #5332S; CST) and Alexa Fluor 594 chicken anti-rabbit secondary antibody (A-21442; Invitrogen). RNA for qRT-PCR

(7) Small extracellular vesicles from young adipose-derived stem cells ameliorate age-related changes in the heart of old miceStem Cell Res TherMarch 13, 2025Jorge Sanz-Ros, Javier Huete-Acevedo, Cristina Mas-Bargues, Nekane Romero-García, Mar Dromant, Michel van Weeghel, Georges E. Janssens, Consuelo Borrás20 (PBS-t) and incubated overnight at 4 °C with a primary antibody against Desmin (Cell Signaling, 5332; 1:500 dilution) and with Alexa Fluor 488 anti-rabbit (Abcam, ab150077; 1:2000 dilution) for 2 h at

(8) Contribution of hypoxia-inducible factor 1alpha to pathogenesis of sarcomeric hypertrophic cardiomyopathySci RepJanuary 16, 2025Sarala Raj Murthi, Andreas Petry, Bachuki Shashikadze, Jan B. Stöckl, Manuel Schmid, Gianluca Santamaria, Karin Klingel, Damir Kračun, Xinpei Chen, Sabine Bauer, et al.incubated with the following primary antibodies: Hif-1α (#36,169, Cell Signaling Technologies), Desmin (#5332, Cell Signaling Technologies), MYH7 (SAB2106550-100U, Sigma Aldrich, Heidelberg), TPM4 (#PA5-92,152,

(9) Acute resistance exercise and training reduce desmin phosphorylation at serine 31 in human skeletal muscle, making the protein less prone to cleavageScientific reportsNovember 14, 2024Jacko D, Schaaf K, Aussieker T, Masur L, Zacher J, Bersiner K, Bloch W, Gehlert S.libitum. Antibodies used for Western blotting Primary: Desmin (D93F5), total (rabbit monoclonal IgG AB; #5332S; 1:1500; Cell Signaling Technology, Danvers, MA, USA); Desmin, total (rabbit polyclonal IgG AB; #PA5-16705;

(10) Honey vesicle-like nanoparticles protect aged liver from non-alcoholic steatohepatitisActa Pharmaceutica Sinica BAugust 1, 2024Baolong Liu, Phuong Linh Nguyen, Han Yu, Xingzhi Li, Huiren Wang, Tram Gia Bao Nguyen, Prakash Kumar Sahoo, Meghna Sur, Jay Reddy, Sarah Sillman, et al.(ProteinTech Group, Cat. No. 10830-1-AP, Rosemont, IL, USA, dilution, 1/200, v/v), DESMIN (Cell Signaling, Cat. No. 5332, dilution, 1/100, v/v), CD146-APC (Milenyi Biotech, Cat. No. 130-102-846, Auburn, CA, USA, dilution,

(11) VGLL2 and TEAD1 fusion proteins drive YAP/TAZ-independent transcription and tumorigenesis by engaging p300bioRxivJuly 2, 2024Susu Guo, Xiaodi Hu, Jennifer L. Cotton, Lifang Ma, Qi Li, Jiangtao Cui, Yongjie Wang, Ritesh P. Thakare, Zhipeng Tao, Y. Tony Ip, et al.and dilutions used in the studies: Ki67 (cat. 12202, 1:500, Cell Signaling Technology), Desmin (cat. 5332, 1:100, Cell Signaling Technology). Statistics and reproducibility Statistical analyses were performed

(12) Inhibition of the glucocorticoid receptor attenuates proteinuric kidney diseases in multiple speciesNephrology Dialysis TransplantationJune 28, 2024Eleni Stamellou, Shipra Agrawal, Florian Siegerist, Marc Buse, Christoph Kuppe, Tim Lange, Eva Miriam Buhl, Jessica Alam, Thiago Strieder, Peter Boor, et al.incubation with the primary and secondary antibodies. The primary antibody was anti-desmin (Rabbit mAB#5332, Cell Signaling). As secondary antibody, we used biotinylated goat anti–rabbit (Vector Laboratories,

(13) Uncovering the mechanisms of MuRF1-induced ubiquitylation and revealing similarities with MuRF2 and MuRF3Biochemistry and Biophysics ReportsMarch 1, 2024Samuel O. Lord, Peter W.J. Dawson, Jitpisute Chunthorng-Orn, Jimi Ng, Leslie M. Baehr, David C. Hughes, Pooja Sridhar, Timothy Knowles, Sue C. Bodine, Yu-Chiang Lai1:10,000) from Clontech, Anti-MYLPF (MF-5, 1:1000) from Developmental Studies Hybridoma Bank, Desmin (5332, 1:1000) from Cell Signalling Technology, Anti-ubiquitin P4D1 (646302, 1:1000) from BioLegend, Anti-ubiquitylated

(14) Dimethyl fumarate modulates the dystrophic disease program following short-term treatmentJCI InsightNovember 8, 2023Cara A. Timpani, Stephanie Kourakis, Danielle A. Debruin, Dean G. Campelj, Nancy Pompeani, Narges Dargahi, Angelo P. Bautista, Ryan M. Bagaric, Elya J. Ritenis, Lauren Sahakian, et al.Cys106 (from Craig Goodman, Centre for Muscle Research, University of Melbourne), anti-Desmin (1:1,000; 5332; Cell Signaling Technology [CST]), anti-DJ1 (1:1,000; 5933; CST), anti-Dystrobrevin (1:500; 610766;

(15) The microtubule signature in cardiac disease: etiology, disease stage, and age dependencyJournal of comparative physiology. B, Biochemical, systemic, and environmental physiologyOctober 1, 2023Algül S, Dorsch LM, Sorop O, Vink A, Michels M, Dos Remedios CG, Dalinghaus M, Merkus D, Duncker DJ, Kuster DWD, et al.mouse anti-acetylated α-tubulin (T7451, Sigma-Aldrich, Saint Louis, MO, USA), rabbit anti-desmin (#5332, Cell Signaling Technology, Danvers, MA, USA), rabbit anti-detyrosinated α-tubulin (ab48389, Abcam,

(16) Myofiber Baf60c controls muscle regeneration by modulating Dkk3-mediated paracrine signalingJournal of Experimental MedicineSeptember 4, 2023Jingya Xu, Xiaofei Li, Wei Chen, Ziyin Zhang, Yanping Zhou, Yahui Gou, Cheng-an Lv, Lu Jin, Xinyuan Qiu, Shengshan Ma, et al.with 10% BSA/PBS for 1 h at room temperature and incubated overnight at 4°C with anti-Desmin (1:200, 5332s; CST), anti-Dystrophin (1:100, ab15277; Abcam), anti-Pax7 (1:200, Pax7-c; DSHB), anti-MyoD (1:500, sc-32758;

(17) Genetic Characterization of Rat Hepatic Stellate Cell Line PAV-1CellsJune 11, 2023Gäberlein K, Schröder SK, Nanda I, Steinlein C, Haaf T, Buhl EM, Sauvant P, Sapin V, Abergel A, Weiskirchen R.Germany",139,1:1000,r mAb Collagen IV,ab6586,"Abcam, Berlin, Germany",161,1:1000,r pAb Desmin (D93F5),#5332,Cell Signaling,53,1:1000,r mAb Fibronectin,AB1954,Sigma-Aldrich,262,1:3000,r pAb GAPDH (6C5),sc-32233,"Santa Cruz

(18) Formation and function of the meningeal arachnoid barrier around the developing mouse brainDevelopmental cellApril 24, 2023Derk J, Como CN, Jones HE, Joyce LR, Kim S, Spencer BL, Bonney S, O'Rourke R, Pawlikowski B, Doran KS, et al.anti-E-cadherin (1:100, BD Transduction Laboratories 610181), rabbit anti-Desmin (1:100, Cell Signaling (5332S), rabbit anti-Lef1 (1:100, Cell Signaling 2230S, rabbit anti-Claudin 11 (1:100, Thermo Fisher, PIPA568608),

(19) Retinoic acid signaling in mouse retina endothelial cells is required for early angiogenic growthDifferentiationMarch 1, 2023Christina N. Como, Cesar Cervantes, Brad Pawlikowski, Julie SiegenthalerCambridge, UK), Iba1 (Cell Signaling, catalog # 17198, Danver, MA), desmin (Cell Signaling, catalog # 5332), GFAP (Cell Signaling, catalog # 3670), or Claudin-5 (4C3C2) Alexa Fluor 488 (catalog #: 352588, Invitrogen,

(20) Establishment of Bactrian Camel Induced Pluripotent Stem Cells and Prediction of Their Unique Pluripotency GenesInternational Journal of Molecular SciencesJanuary 18, 2023Zongshuai Li, Yina Li, Qiran Zhang, Wenbo Ge, Yong Zhang, Xingxu Zhao, Junjie Hu, Ligang Yuan, Wangdong Zhanganti-rabbit FOX2 (1:400; CST, Danvers, MA, USA; 8186T), anti-rabbit DES (1:400; CST, Danvers, MA, USA; 5332T), anti-mouse GFAP (1:300; CST, Danvers, MA, USA; 3670T), and anti-mouse β-tubulin (1:200; Santa, Dallas,

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Desmin (D93F5) XP ® Rabbit mAb

Desmin (D93F5) XP ® Rabbit mAb from Cell Signaling Technology

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Desmin (D93F5) XP ® Rabbit mAb from Cell Signaling Technology

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