PDHK1 (C47H1) Rabbit mAb 3820S from Cell Signaling Technology

Product Specs
ItemPDHK1 (C47H1) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number3820S
Quantity100 µl
ApplicationsW, IP
ReactivityH, M, R, Mk
TargetPDHK
HostRabbit
ClonalityMonoclonal
NCBI Full Gene Namepyruvate dehydrogenase kinase 1
Research AreaMetabolism
IsotypeIgG
CloneC47H1
Molecular Weight47

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) A Hierarchical Microglial-Targeting Nanoplatform for the Therapy of Parkinson’s Disease by Modulating Mitochondrial DysfunctionPharmaceuticsFebruary 22, 2026Yue Xing, Shumeng Liu, Yue Na, Hao Wu, Chi Liu, Bohan Zhang, Zhigang Wang, Xiuhong Wu, Ning Zhang, Fang Geng(CST, Shanghai, China)",17198 Anti-PDH antibody,"Cell Signaling Technology (CST, Shanghai, China)",3820 Anti-PDH (Ser293) antibody,"Cell Signaling Technology (CST, Shanghai, China)",37115 Anti-PDH (Ser232)

(2) Mild Short-Term Caloric Restriction Induces Coordinated Changes That Promote Lipid Deposition While Maintaining Thermogenesis Capacity in Interscapular Brown Adipose Tissue of Male RatsFASEB JFebruary 15, 2026Giuliana Panico, Vincenzo Migliaccio, Gabriella Pinto, Anna Iliano, Gianluca Fasciolo, Martina Coletta, Paola Venditti, Maria Moreno, Angela Amoresano, Pieter de Lange, et al.phosphoglycerate mutase 1 (PGAM1 12 098 Cell Signaling Technology), anti pyruvate dehydrogenase Kinase (PDHK1 3820 Cell Signaling Technology), anti Enolase (ENO 3810, Cell Signaling Technology), anti mitochondrial pyruvate

(3) Senescent Fibroblasts Drive Melanoma Progression Through GCP ‐2 Induced CREB Phosphorylation Enhancing GlycolysisAging CellNovember 19, 2025Abhijit Basu, Vida Farsam, Karmveer Singh, Diana Crisan, Nicolai Treiber, Lars Alexander Schneider, Margit Huber, Jennifer I. Engelmeyer, Björn Schumacher, Pallab Maity, et al.#D3E9; Cell Signaling Technologies), (pCS1 #SC33397; Santacruz), (pPDH‐E1a #AP1062; Millipore), (PDHK1 #3820; LDHA/C #3558; ACO2 #6571; Cell signaling Technologies) and (Ki67; SP6; Thermo Scientific). Isotype

(4) FGF2 supports NANOG expression via pyruvate dehydrogenase–dependent histone acetylation under low oxygen conditionsFrontiers in Cell and Developmental BiologyOctober 28, 2025Petr Fojtík, Martin Senfluk, Katerina Holomkova, Anton Salykin, Jana Gregorova, Pavel Smak, Ondrej Pes, Jan Raska, Deborah Beckerova, Monika Stetkova, et al.,Cell Signaling Technology pPDH (Ser293),1:1000,RRID:AB_10616069,AP1062,Calbiochem PDHK1,1:1000,RRID:AB_1904078,3820,Cell Signaling Technology PDP1,1:1000,RRID:AB_2799686,"65,575",Cell Signaling Technology Vinculin,1:2000,RRID:AB_2728768,"13,901",Cell

(5) Anticancer Effects of Ascorbic Acid: Not All Sides Fit AllCancers (Basel)September 1, 2025Uche O. Arunsi, Jeremiah O. Olugbami, Adegboyega K. Oyelere5% BSA for 1–2 h, the membrane was incubated overnight with primary antibodies PDHK1 (1:1000, Cat #.3820, Cell Signaling Technology, Danvers, MA, USA) and anti-GAPDH (Aldrich-Sigma, Saint Louis, MO, USA).

(6) PDK1-dependent metabolic reprogramming regulates stemness and tumorigenicity of osteosarcoma stem cells through ATF3Cell Death DisJuly 29, 2025Kazuya Tokumura, Kazuya Fukasawa, Jiro Ichikawa, Koki Sadamori, Manami Hiraiwa, Eiichi Hinoiwere used. Primary antibodies: anti-PDK1 (1:1000, Cell Signaling Technology, CST, Danvers, MA, USA, #3820), anti-PDH (1:1000, CST, #2784), anti-p-PDH (1:1000, CST, #31866), anti-SOX2 (1:1000, CST, #14962),

(7) Redirecting glucose flux during in vitro expansion generates epigenetically and metabolically superior T cells for cancer immunotherapyCell MetabolismApril 1, 2025Andrew T. Frisch, Yiyang Wang, Bingxian Xie, Aaron Yang, B. Rhodes Ford, Supriya Joshi, Katarzyna M. Kedziora, Ronal Peralta, Drew Wilfahrt, Steven J. Mullett, et al.2784S, RRID:AB_2162928" anti-mouse PDHK1 (C47H1) (rabbit monoclonal),Cell Signaling Technology,"Cat# 3820T, RRID:AB_1904078" anti-mouse Actin Antibody (C-2) (mouse monoclonal),Santa Cruz Bio,"Cat# sc-8432,

(8) Glutamine Oxidation in Mouse Dorsal Root Ganglia Regulates Pain Resolution and ChronificationJ NeurosciNovember 20, 2024Md Mamunul Haque, Panjamurthy Kuppusamy, Ohannes K. MelemedjianABS204, 07-1223), PDH, LDHA, PDHK1, ASCT2 (1:1,000, Cell Signaling Technology, catalog #3205, 3582, 3820, 5345), and beta-III-tubulin (1:50,000, Promega, catalog #G7121). Statistical analysis and data presentation Data

(9) Inhibition of the ubiquitin-proteasome system reduces the abundance of pyruvate dehydrogenase kinase 1 in cultured myotubesJournal of Muscle Research and Cell MotilitySeptember 1, 2024Blaž Kociper, Nives Škorja Milić, Ivana Ogrizek, Katarina Miš, Sergej Pirkmajerh p-PDHE1α (Ser293),43,Abcam,ab92696,Rb,1:1000,O/N,O/N,Bio-Rad,1706515,"1:50,000",1 h,1 h PDK1,47,CST,3820,Rb,1:1000,O/N,O/N,Bio-Rad,1706515,"1:5,000",1 h,1 h STAT3,"79, 86",CST,4904,Rb,1:1000,O/N,O/N,Bio-Rad,1706515,"1:15,000",5

(10) Disruption of mitochondrial pyruvate oxidation in dorsal root ganglia drives persistent nociceptive sensitization and causes pervasive transcriptomic alterationsPainJuly 1, 2024Md Mamunul Haque, Panjamurthy Kuppusamy, Ohannes K. MelemedjianABS204, 07-1223), PDH, LDHA, PDHK1 (1:1000, Cell Signaling Technology, Danvers, MA, Cat # 3205, 3582, 3820), and beta-III-tubulin (1:50,000, Promega, Madison, WI, Cat # G7121). 2.8. Poly(A) RNA isolation, library

(11) A small molecule macrophage migration inhibitory factor agonist ameliorates age-related myocardial intolerance to ischemia-reperfusion insults via metabolic regulationMetabolismApril 1, 2024Hao Wang, Lily Slotabec, Steven Didik, Zehui Li, Lin Leng, Bi Zhao, Richard Bucala, Ji Li(Santa Cruz Biotechnology, sc-377092, source: mouse, monoclonal), PDK1 (Cell Signaling Technology, Cat #3820, source: rabbit, monoclonal), phosphofructokinase-2 (PFKFB2) (Cell Signaling Technology, Cat #13045,

(12) Exploring the limitations of mitochondrial dye as a genuine horizontal mitochondrial transfer surrogateCommunications biologyMarch 7, 2024Chen C, Li H, Zhang J, Cheng SC.synthase (CS, #14309, Cell signaling technology, 1:1000), anti-pyruvate dehydrogenase kinase 1 (PDHK1, #3820, Cell signaling technology, 1:1000), anti-TOM20 (#11802-1-AP, Proteintech, 1:1000), and anti- Actin

(13) Pyruvate Dehydrogenase-Dependent Metabolic Programming Affects the Oligodendrocyte Maturation and RemyelinationMolecular NeurobiologyJanuary 1, 2024M. Sajad, Insha Zahoor, Faraz Rashid, Mirela Cerghet, Ramandeep Rattan, Shailendra Giriused were O4: R&D Systems-MAB1326, MBP: Cell Signaling 78896, Flag: Pdhk1: Catalog: Cell Signaling 3820, and p-Pdh Ser-293, for the quantification of MBP-expressing OLs, they were imaged using LSCM with 1

(14) Aspirin reprogrammes colorectal cancer cell metabolism and sensitises to glutaminase inhibitionCancer & MetabolismOctober 19, 2023Amy K. Holt, Arafath K. Najumudeen, Tracey J. Collard, Hao Li, Laura M. Millett, Ashley J. Hoskin, Danny N. Legge, Eleanor M. H. Mortensson, Dustin J. Flanagan, Nicholas Jones, et al.(16,757–1-AP, ProteinTech, Group, Inc.), LAT1 (5347, CST), PC (ab126707, Abcam, Cambridge, UK), PDK1 (3820, CST), HK1 (2024, CST), and GLUT1 (21,829–1-AP20, Proteintech, Group, Inc.). All were used at 1:1000

(15) Evidence for Hypoxia-Induced Shift in ATP Production from Glycolysis to Mitochondrial Respiration in Pulmonary Artery Smooth Muscle Cells in Pulmonary Arterial HypertensionJournal of Clinical MedicineJuly 31, 2023Satoshi Akagi, Kazufumi Nakamura, Megumi Kondo, Satoshi Hirohata, Heiichiro Udono, Mikako Nishida, Yukihiro Saito, Masashi Yoshida, Toru Miyoshi, Hiroshi Itogel and blotted onto nitrocellulose membranes. Blots were incubated with anti-PDK1 antibody (1:1000; #3820; Cell Signaling Technology, Danvers, MA, USA), anti-PDH phospho S293 (1:1000; ab177461, Abcam, Cambridge,

(16) Time-dependent effects of hypoxia on cell metabolism, signaling, and iron homeostasis in the hematopoietic progenitor model KG1aFEBS open bioJuly 1, 2023Nahoui-Zarouri I, Léger C, El Samra G, Cottet-Rousselle C, Moulis JM.#2983 p‐T37/46‐4E‐BP1,,236B4 #2855 4E‐BP1,,#9452 eIF4E,,C46H6 #2067 PDK1 (as PDHK1 at CST),,C47H1 #3820 PFKP,,D4B2 #8164 LC3A/B,,D3U4C #12741 CD71 (Transferrin Receptor 1),,D7G9X #13113 FTH1,,D1D4 #4393 IRP1,Home

(17) Integrative proteogenomic characterization of early esophageal cancerNature CommunicationsMarch 25, 2023Lingling Li, Dongxian Jiang, Qiao Zhang, Hui Liu, Fujiang Xu, Chunmei Guo, Zhaoyu Qin, Haixing Wang, Jinwen Feng, Yang Liu, et al.Catalog: C11596, dilution 1:500), Anti-PDHK1 (Cell Signaling Technology, Danvers, MA, USA, Catalog: 3820, dilution 1:1000), Anti-ERK2 (Cell Signaling Technology, Danvers, MA, USA, Catalog: 9108, dilution 1:1000),

(18) Osteocalcin ameliorates cognitive dysfunctions in a mouse model of Alzheimer's Disease by reducing amyloid β burden and upregulating glycolysis in neurogliaCell death discoveryFebruary 6, 2023Shan C, Zhang D, Ma DN, Hou YF, Zhuang QQ, Gong YL, Sun LH, Zhao HY, Tao B, Yang YY, et al.BioLegend), mouse anti-Gapdh (1: 5000 dilution, ab8245, Abcam), rabbit anti Pdk-1 (1: 500 dilution, 3820 S, Cell Signaling Technology), rabbit anti-Ldha (1: 1000 dilution, 2012S, Cell Signaling Technology),

(19) Leucine and Arginine Availability Modulate Mouse Embryonic Stem Cell Proliferation and MetabolismInternational journal of molecular sciencesNovember 18, 2022Correia B, Sousa MI, Branco AF, Rodrigues AS, Ramalho-Santos J.rabbit anti-SDHA (Cat.No:#11998; Cell Signaling, Danvers, MA, USA, 1:1000), rabbit anti-PDHK1 (Cat.No:#3820, Cell Signaling, Danvers, MA, USA; 1:1000), rabbit anti-p-LDHA (Tyr10) (Cat.No:#8176, Cell Signaling,

(20) N-glycosylation stabilizes MerTK and promotes hepatocellular carcinoma tumor growthRedox biologyAugust 1, 2022Liu Y, Lan L, Li Y, Lu J, He L, Deng Y, Fei M, Lu JW, Shangguan F, Lu JP, et al.501965), LDHA (ZN; 501146), PFKM (ZN; 505477), PKM2 (ZN; 505477), PDHK1 (Cell Signaling Technology; 3820S), Lamin B (Proteintech; 12987-1-AP), GAPDH (Abmart; M20028) and β-Actin (Proteintech; 60008-1-1 g). 2.5

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3/18/2019Expression of PDHK1 in Western Blot of Tumor Cells Meng SunDefinitely a great antibody for detecting PDHK1 in western blots, in tumor cells, and T cells

PDHK1 (C47H1) Rabbit mAb

PDHK1 (C47H1) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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PDHK1 (C47H1) Rabbit mAb from Cell Signaling Technology

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