Oct-4 (9B7) Mouse mAb 4286S from Cell Signaling Technology

Product Specs
ItemOct-4 (9B7) Mouse mAb
CompanyCell Signaling Technology
Price $336.00 Inquire
Catalog Number4286S
Quantity100 µl
ApplicationsW, IP
ReactivityH, M
TargetOct4A
HostMouse
NCBI Gene AliasesOCT3, OCT4, OTF-3, OTF3, OTF4, Oct-3, Oct-4, Oct3/4
ClonalityMonoclonal
NCBI Full Gene NamePOU class 5 homeobox 1
Research AreaDevelopmental Biology
IsotypeIgG1
Clone9B7
Molecular Weight45

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Evaluation of dECM hydrogel-NAP on 3D organotypic human corneal epithelium in diabetic keratopathy modelScientific ReportsJanuary 14, 2026Simona Casarella, Nicoletta Palmeri, Agata Grazia D’Amico, Assunta Virtuoso, Salvatore Saccone, Elisabetta Pricoco, Davide Scollo, Antonio Longo, Michele Papa, Francesca Boccafoschi, et al.USA); anti-cleaved caspase 3 (#9661, Cell Signaling Technology); anti-Ki-67 (30 − 9) (cat. no. 790–4286, Roche); anti- β-actin (C4) (SC-47778, Santa Cruz Biotechnology). The secondary antibody, goat anti-rabbit

(2) PI3Kα Inhibitor and Degrader Inavolisib Can Co-opt FGFR2 to Enhance Responses in Patients with PIK3CA -Mutated Solid Tumors and in Preclinical ModelsClinical Cancer ResearchNovember 20, 2025Dejan Juric, Kyung Song, Radia M. Johnson, Melissa K. Accordino, Philippe L. Bedard, Andrés Cervantes, Valentina Gambardella, Erika Hamilton, Antoine Italiano, Kevin Kalinsky, et al.analysis with antibodies against Ki67 (rabbit mAb, clone 30-9, Ventana/Roche Diagnostics, cat. No. 790-4286, RRID: AB_2631262), phosphorylated AKT (pAKT; Ser473; D9E XP rabbit mAb, Cell Signaling Technology,

(3) PI3Kα Inhibitor and Degrader Inavolisib Can Co-opt FGFR2 to Enhance Responses in Patients with PIK3CA-Mutated Solid Tumors and in Preclinical ModelsClin Cancer ResOctober 27, 2025Dejan Juric, Kyung Song, Radia M. Johnson, Melissa K. Accordino, Philippe L. Bedard, Andrés Cervantes, Valentina Gambardella, Erika Hamilton, Antoine Italiano, Kevin Kalinsky, et al.analysis with antibodies against Ki67 (rabbit mAb, clone 30-9, Ventana/Roche Diagnostics, cat. No. 790-4286, RRID: AB_2631262), phosphorylated AKT (pAKT; Ser473; D9E XP rabbit mAb, Cell Signaling Technology,

(4) BCL2 drives castration resistance in castration-sensitive prostate cancer by orchestrating reciprocal crosstalk between oncogenic pathwaysCell ReportsJune 24, 2025Rahim Hirani, Subhiksha Nandakumar, Nabila Zaman, Prathiksha Prabhakaraalva, Sarah Ann King, Teja Muralidhar Kalidindi, Romina Ghale, Sai Harisha Rajanala, Deborah C. Fidele, Elisa De Stanchina, et al.Polyclonal,Cell Signaling,Cat#9552; RRID:AB_10694066 KI-67 (30–9); Rabbit Monoclonal,Ventana/Roche,Cat#790–4286 Vimentin; Rabbit Monoclonal,Cell Signaling,Cat#5741; RRID:AB_10695459 E-cadherin; Mouse Monoclonal,BD

(5) Creation and Characterization of a Breast Cancer Tissue Microarray Including Black and White Patients from Florida and Hispanic Patients from Puerto Rico and FloridaCancer Res CommunMay 1, 2025Abigail E. Lantz, Edna R. Gordián, Marilin Rosa, Marileana Rodríguez-Ruíz, Joseph O. Johnson, Ryan Gebert, Allison Bahr, Dung Tsa Chen, Julie Dutil, Jiannong Li, et al.AB_2857956), (ii) PR (Ventana, cat. # 790-2223, RRID: AB_2335976), (iii) Ki-67 (Ventana, cat. # 790-4286, RRID: AB_2631262), and HER2 (Cell Signaling Technology, cat. #4290, RRID: AB_10557104). Additional

(6) Creation and characterization of a breast cancer tissue microarray including Black and White patients from Florida and Hispanic patients from Puerto Rico and FloridaCancer Res CommunMay 1, 2025Abigail E. Lantz, Edna R. Gordián, Marilin Rosa, Marileana Rodríguez Ruíz, Joseph O. Johnson, Ryan Gebert, Allison Bahr, Dung Tsa Chen, Julie Dutil, Jiannong Li, et al.AB_2857956), (ii) PR (Ventana, cat. # 790-2223, RRID: AB_2335976), (iii) Ki-67 (Ventana, cat. # 790-4286, RRID: AB_2631262), and HER2 (Cell Signaling Technology, cat. #4290, RRID: AB_10557104). Additional

(7) Co-Inhibition of tGLI1 and GP130 Using FDA-Approved Ketoconazole and Bazedoxifene Is Synergistic Against the Growth and Metastasis of HER2-Enriched and Triple-Negative Breast CancersCellsDecember 17, 2024Manore S, Zhuang C, Najjar MK, Wong GL, Bindal S, Watabe K, Lin J, Lo HW.GP130 (CST 3732, 1:1000), pSTAT3 (CST 9131L, 1:1000), STAT3 (CST 9139, 1:1000), OCT4 (CST 2750 and CST 4286, 1:1000), Nanog (CST 4903, 1:1000), SOX2 (CST 4900, 1:1000), Cyclin D1 (CST 2922, 1:1000), Bcl2 (CST

(8) Identification of cellular and noncellular components of mature intact human peripheral nerveJournal of the Peripheral Nervous SystemSeptember 1, 2024Gabriela I. Aparicio, Jorge E. Quintero, Lauren Plum, Lingxiao Deng, Kristen Wanczyk, Miriam Henry, Evan Lynch, Michael Murphy, Greg A. Gerhardt, Craig G. van Horne, et al.IV,1042,Collagen IV-Alexa488,Thermo Fisher,53-9871-82,1:50,- MKi-67,30-9,Rabbit IgG mAb,Roche - Ventana,790-4286,-,1:100 / 1 h CC3,ASP175,Rabbit IgG mAB,Cell Signaling,9661,-,1:150 / 1 h Primary antibodies used

(9) Effects of Topoisomerase II alpha Inhibition on Oral Cancer Cell Metabolism and Cancer Stem Cell FunctionDental Research and Oral HealthJuly 3, 2024Thanigaivelan Kanagasabai, Mariam Hawaz, Kayla Ellis, Orlyne Fah, Helana Mikhaeil, Philip Nguyen, Nathalie Tombo, Anil Shanker, Chethan Sampath, Zaid H Khoury, et al.Survivin (Cell signaling # 2808, 1:1000), IL-6 (Santa Cruz # sc-130326, 1:500), Oct-4 (Cell signaling # 4286, 1:1000), Sox2 (Cell signaling # 23064, 1:1000) and β-Actin (Cell Signaling # 3700, 1:1000). RIPA cell lysis

(10) KDF1 Promoted Proliferation, Migration and Invasion of Lung Adenocarcinoma Cells through Activating STAT3 and AKT PathwayBiomedicinesDecember 1, 2023Guo YQ, Gan MF, Bao JQ, Zhou HX, Yang J, Dai CJ, Zheng JM.(p-STAT3) antibody (Cat.No. 9145S, CST, Danvers, MA, USA, dilution 1:200), Ki-67 antibody (Cat.No. 790-4286, Roche, AZ, USA, dilution 1:2) and horseradish-peroxidase-labeled second antibody (Cat.No. RQ7025, Quanhui,

(11) GSK-3484862 targets DNMT1 for degradation in cellsNAR CancerMay 17, 2023Qin Chen, Bigang Liu, Yang Zeng, Jee Won Hwang, Nan Dai, Ivan R Corrêa, Marcos R Estecio, Xing Zhang, Margarida A Santos, Taiping Chen, et al.#5032), DNMT3A (CST, #3598), DNMT3B (CST, #67259), H3 (CST, #14269), GAPDH (CST, #2118), Oct4 (CST, #4286), PCNA (CST, #13110), Uhrf1 (CST, #12387), Actin (Sigma-Aldrich, A2228), Myc tag (Sigma-Aldrich, M4439),

(12) Metastatic prostate cancer diagnosed by fine‐needle aspiration: Contemporary cytopathologic and biomarker assessment with clinical correlatesCancer CytopathologyFebruary 1, 2023Richard L. Cantley, Xiaoming Wang, Zachery R. Reichert, Arul M. Chinnaiyan, Rahul Mannan, Xuhong Cao, Daniel E. Spratt, Ulka N. Vaishampayan, Joshi J. Alumkal, Todd M. Morgan, et al.(Ventana 760‐4605), synaptophysin (Ventana 790‐4407), chromogranin (Ventana 760‐2519), Ki‐67 (Ventana 790‐4286), PTEN (Cell Signaling 9188), ERG (Ventana 790‐4576), PDL1 (Spring Biosciences M4420), RB protein (Cell Signaling

(13) Developing 3D Organoid Raft Cultures from Patient-Derived Xenografts as Rapid Models to Screen Efficacy of Experimental TherapeuticsInternational journal of molecular sciencesNovember 19, 2022Bajpai P, Banerjee NS, Moore DW, Kim HG, Afaq F, Contreras CM, Heslin MJ, Reddy VB, Peter S, Varambally S, et al.Danvers, MA, USA), BCL-W (Cat #2724, Cell Signaling Technology, Danvers, MA, USA) and Ki67 (Cat # 790-4286, Roche, Indianapolis, IN, USA) protein for 1 h at room temperature. After three washes with 0.5% Tween

(14) An FDA-Approved Antifungal, Ketoconazole, and Its Novel Derivative Suppress tGLI1-Mediated Breast Cancer Brain Metastasis by Inhibiting the DNA-Binding Activity of Brain Metastasis-Promoting Transcription Factor tGLI1CancersAugust 31, 2022Doheny D, Manore S, Sirkisoon SR, Zhu D, Aguayo NR, Harrison A, Najjar M, Anguelov M, Cox AO, Furdui CM, et al.(CST; 2643, 1:1000), a custom-made tGLI1-specific antibody (Yenzyme, 1:1000), OCT4 (CST 2750 and CST 4286, 1:1000), Nanog (CST 4903, 1:1000), androgen receptor (CST 5153, 1:1000), α-Tubulin (Sigma T6074, 1:5000),

(15) Differentiation of cancer stem cells into erythroblasts in the presence of CoCl₂Scientific reportsDecember 14, 2021Kumon K, Afify SM, Hassan G, Ueno S, Monzur S, Nawara HM, Quora HAA, Sheta M, Xu Y, Fu X, et al.secondary antibody. The primary antibodies used were anti-Oct-4A (9B7) mouse monoclonal IgG (1: 1000, #4286, Cell Signaling Technology, MA), anti-HIF-1α mouse monoclonal IgG1 clone # 241,809 (1: 1000, R&D Systems,

(16) Modulation of the immune microenvironment of high-risk ductal carcinoma in situ by intralesional pembrolizumab injectionnpj Breast CancerDecember 1, 2021Alexa C. Glencer, Jasmine M. Wong, Nola M. Hylton, Gregor Krings, Emma McCune, Harriet T. Rothschild, Tristan A. Loveday, Michael D. Alvarado, Laura J. Esserman, Michael J. CampbellCell Signaling Technology, Danvers, MA), and Ki67 (proliferation marker, clone 30–9, ready to use, cat# 790–4286, Ventana/Roche). Each section was run through sequential rounds of heat-inactivation epitope retrieval

(17) Patient-derived ovarian cancer explants: preserved viability and histopathological features in long-term agitation-based culturesScientific ReportsDecember 1, 2020Sofia Abreu, Fernanda Silva, Rita Mendes, Teresa F. Mendes, Marta Teixeira, Vítor E. Santo, Erwin R. Boghaert, Ana Félix, Catarina Britostatus were assessed (N = 13) by labelling Ki67 (anti-Ki67, clone 30-9, pre-diluted, Cat. Number 790-4286) and cleaved caspase-3 (cleaved caspase-3, clone Asp 175, dilution 1:100, Cat. Number 9661, Cell Signaling),

(18) Clinicopathological and Molecular Characteristics of Pleomorphic Invasive Lobular CarcinomaInternational Journal of Breast CancerNovember 22, 2020Jennifer M. Segar, Ritu Pandey, Kiah J. Farr, Raymond Nagle, Lauren LeBeau, Victor J. Gonzalez, Pavani Chalasanifrom the FFPE blocks. Immunohistochemistry (IHC) was performed for Ki67 by using Ventana Antibody #790-4286 (Rabbit primary monoclonal antibody), for PTEN by Cell Signaling Technologies #9188 (clone D4.3, XP

(19) Whole exome sequencing reveals the maintained polyclonal nature from primary to metastatic malignant peripheral nerve sheath tumor in two patients with NF1Neuro-oncology advancesJuly 1, 2020Godec A, Jayasinghe R, Chrisinger JSA, Prudner B, Ball T, Wang Y, Srihari D, Kaushal M, Dietz H, Zhang X, et al.1:500 (Cell Signaling Technology, Danvers, MA) with citrate antigen retrieval or prediluted Ki67 (790– 4286; Ventana) with CC1 buffer (950- 124, Ventana) antigen retrieval was performed on subcutaneous tumor

(20) Down-Regulation of ZEB1 by miR-199a-3p Overexpression Restrains Tumor Stem-Like Properties and Mitochondrial Function of Non-Small Cell Lung CancerOncoTargets and TherapyMay 22, 2020Juan Bai, Wen-Yu JiaoAbcam (Cambridge, UK). And anti-ZEB1 (#3396), anti-SOX-2 (#2748), anti-ALDH-1 (#12035), anti-OCT4 (#4286), anti-Bax (#2772), anti-Bcl-2 (#4223), anti-GAPDH (#51332) and all secondary antibodies were from Cell Signaling Technology

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Oct-4 (9B7) Mouse mAb

Oct-4 (9B7) Mouse mAb from Cell Signaling Technology

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Cell Signaling Technology

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Oct-4 (9B7) Mouse mAb from Cell Signaling Technology

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