Atg12 (D88H11) Rabbit mAb 4180S from Cell Signaling Technology

Product Specs
ItemAtg12 (D88H11) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number4180S
Quantity100 µl
ApplicationsW, IP
ReactivityH, M, R, Mk
TargetATG12
HostRabbit
NCBI Gene AliasesAPG12, APG12L, FBR93, HAPG12
ClonalityMonoclonal
NCBI Full Gene Nameautophagy related 12
Research AreaAutophagy
IsotypeIgG
CloneD88H11
Molecular Weight16, 55

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Cell Signaling Technology

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Phone: 978-867-2388
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Website: http://www.cellsignal.com/

Website: Technical Support

(1) TANK-binding kinase 1 protects against MASH progression via mitochondrial quality controlExperimental & Molecular MedicineMarch 13, 2026Sung-Min An, Jun Hee Jang, Jin Hyun Sung, Ji Won Myung, Yong Geun Jeon, Won Taek Lee, Jin Won Jeon, Kyung Min Yim, Jae-Ho Lee, Bichen Zhang, et al.cleaved caspase 3 (9661), pY705 STAT3 (9131), STAT3 (9139), pT108/Y182 p38 (9211), p38 (9212), ATG12 (4180), ATG5 (12994), ATG7 (8558), pS403 p62 (39786), p62 (5114), TOM20 (42406), LC3 (12741), pS2481 mammalian

(2) Coronavirus Nsp3 Hijacks CLTC to Modulate Autophagosome Nucleation for Promoting DMV Formation and Viral ReplicationAdvanced ScienceFebruary 21, 2026Juan Xu, Hang Li, Peng Liu, Zhe Jiao, Ding Zhang, Zhelin Su, Sai Niu, Jintao Zhang, Yuejun Shi, Guiqing Peng(Cell Signaling Technology: 12994S; 1:1000), rabbit monoclonal anti‐ATG12 (Cell Signaling Technology: 4180T; 1:1000), rabbit monoclonal anti‐ATG16L1 (Cell Signaling Technology: 8089S; 1:1000), rabbit monoclonal

(3) Selective vulnerability of the aging cholinergic system to amyloid pathology revealed by induced APP overexpressionJournal of NeuroinflammationJanuary 7, 2026Kan Xie, Devon Ryan, Susanne Schröder, Lena Freund, Stefan Bonn, Yu Zhou, Dan Ehningeranti-ATG7 (#8558, clone D12B11, 1:2,000; Cell Signaling Technology), rabbit monoclonal anti-ATG12 (#4180, clone D88H11, 1:2,000; Cell Signaling Technology), rabbit monoclonal anti-beclin 1 (#3495, clone D40C5,

(4) Enterohemorrhagic Escherichia coli targets Annexin A6 and ATG16L1 to inhibit autophagy and induce inflammationAIMS MicrobiologyDecember 17, 2025Litai Xu, Department of Microbiology; BSL-3 Laboratory (Guangdong), Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, China, Min Gao, Yaoguo Wang, Bao Zhang, Wei Zhao, Weizhi Lu, Guanhua Cao, Chengsong Wan, Ying Hua, et al.anti-ATG5,Cell Signaling Technology,12994S,1:2000 monoclonal rabbit anti-ATG12,Cell Signaling Technology,4180S,1:2000 monoclonal rabbit anti-Beclin1,Cell Signaling Technology,3495S,1:2000 monoclonal rabbit anti-Akt,Cell Signaling Technology

(5) Combination treatment of cordycepin and radiation induces apoptosis accompanied by protective autophagy in TM3 mouse Leydig progenitor cellsJournal of Food and Drug AnalysisDecember 15, 2025Yu-Yan Lan, Yi-Ping Lee, Wei-Ru Huang, Chun-Ying Yu, Lyh-Jyh Hao, Chun-Hung Lin, Bu-Miin Huangno. 12994, monoclonal rabbit IgG, 1:2000 dilution, Cell Signaling, Boston, MA, USA), Atg12 (cat. no. 4180, monoclonal rabbit IgG, 1:2000 dilution, Cell Signaling, Boston, MA, USA), or Beclin-1 (cat. no. 3495,

(6) Stra8 links neuronal activity to inhibitory circuit protection in the adult mouse brainCell ReportsNovember 25, 2025Ming Huang, Shuwen Yue, Xiaoyu Zhang, Lan Wu, Jay L. Vivian, Zi-Jun Wang, Ning WangAB_2797913 Atg101,Cell Signaling Technology,Cat#13492T; RRID: AB_2798234 Atg12,Cell Signaling Technology,Cat#4180P; RRID: AB_1903898 Atg5,Cell Signaling Technology,Cat#12994P; RRID: AB_2630393 GFP,Abcam,Cat#ab13970;

(7) Multiomics profiling reveals that P. gingivalis-induced extracellular vesicle reprogramming promotes immune evasion in colorectal cancer through autophagy-mediated STING degradationFront Cell Infect MicrobiolOctober 15, 2025Xu Zhang, Jieying Huang, Guangwei Shang, Yang Lu, Haixia Liu, Yiming Zhang, Fuping Wen, Yuanzhi Xuanti-MMP2 (ab92536, Abcam); anti-ATG5 rabbit mAb (12994, Cell Signaling Technology); anti-ATG12 rabbit mAb (4180, Cell Signaling Technology); anti-SQSTM1/p62 rabbit mAb (39749, Cell Signaling Technology); anti-LC3B

(8) Tank-Binding Kinase 1 protects against MASH progression via mitochondrial quality controlResearch SquareOctober 10, 2025Jin Young Huh, Sung-Min An, Jun Hee Jang, Jin Hyun Sung, Ji Won Myung, Yong Geun Jeon, Won Taek Lee, Jin Won Jeon, Kyung Min Yim, Jae-Ho Lee, et al.cleaved caspase 3 (9661), pY705 STAT3 (9131), STAT3 (9139), pT108/Y182 p38 (9211), p38 (9212), ATG12 (4180), ATG5 (12994), ATG7 (8558), pS403 p62 (39786), p62 (5114), TOM20 (42406), LC3 (12741), pS2481 mTOR

(9) CryoSift - An accessible and automated CNN-driven tool for cryo-EM 2D class selectionbioRxivAugust 1, 2025Jan-Hannes Schäfer, Austin Calza, Keenan Hom, Puneeth Damodar, Ruizhi Peng, Nebojša Bogdanović, Gabriel C. Lander, Scott M. Stagg, Michael A. Cianfroccoligase,11734,41996,PreP,10937,22278,RNApol,10709,12885* Antibody,11341,28537*,ALK,10930,24095,PA3488,11204,32438* AP2 Tgn38,11605,24712*,CST,10718,21567,GS-GN,11139,14587* AP2 Heparin,11604,24711,RNAPol-III,10168,4180,FAsyn,10470,4578* Pks13,11608,26574,RAG1-2,10049,6487,Cas7-11,11268,14848* MSG,11167,34029,N2ase,11795,26764*,T20S,10025,6287* Aldolase,10379,21492*,PRex-1G,10285,20308*,CDK,10561,12042 MAVS,10031,6428,HA-trimer,10097,8731,7TM-1G,10288,0339 Publicly

(10) m6A alters ribosome dynamics to initiate mRNA degradationCellJuly 10, 2025Shino Murakami, Anthony O. Olarerin-George, Jianheng Fox Liu, Sara Zaccara, Ben Hawley, Samie R. Jaffreyantibody. For immunostaining experiments, we used anti-ATG12 rabbit monoclonal antibody (Cell Signaling, 4180T) and anti-ULK1 rabbit monoclonal antibody (Cell Signaling, 8054T) as primary antibodies. We used Alexa

(11) AIMP3 maintains cardiac homeostasis by regulating the editing activity of methionyl-tRNA synthetaseNature Cardiovascular ResearchJune 25, 2025Anindhya S. Das, Charles P. Rabolli, Colton R. Martens, Han-Kai Jiang, Yingshen Zhang, Aubree A. Zimmer, Kevin Lin, Kedryn K. Baskin, Juan D. Alfonzo, Federica Accorneroanti-p62 (CST, 39749S), anti-BAG3 (Proteintech, 68076-1-Ig), anti-BECLIN-1 (CST, 3495), anti-ATG12 (CST, 4180), anti-LC3I/II (CST, 12741), anti-Myc (Proteintech, 16286-1-AP) and anti-poly-ubiquitin (CST, 20326).

(12) PLK1-mediated PDHA1 phosphorylation drives mitochondrial dysfunction, mitophagy, and cancer progression in Cr(VI)-associated lung cancerJournal of Biological ChemistryJune 20, 2025Qiongsi Zhang, Jia Peng, Zhiguo Li, Xiongjian Rao, Derek B. Allison, Qi Qiao, Zhuangzhuang Zhang, Yifan Kong, Yanquan Zhang, Ruixin Wang, et al.RRID:AB_10622025), HA(Cell Signaling Technology Cat# 3724, RRID:AB_1549585), ATG12 (Cell Signaling Technology Cat# 4180, RRID:AB_1903898), P62(Cell Signaling Technology Cat# 39749, RRID:AB_2799160), PINK1(Cell Signaling Technology

(13) Phosphoribosyl ubiquitination of SNARE proteins regulates autophagy during Legionella infectionThe EMBO JournalJune 12, 2025Rukmini Mukherjee, Anshu Bhattacharya, Ines Tomaskovic, João Mello-Vieira, Melinda Elaine Brunstein, Marion Başoğlu, Tineke Veenendaal, Henry Bailey, Thomas Colby, Mohit Misra, et al.Cell Signaling Technology; 1:2000), ATG16L (cat. no. ab188642, Cell Signaling Technology; 1:1000), ATG12 (cat. no. 4180, Cell Signaling Technology; 1:1000), Beclin1 (cat. no. 3738, Cell Signaling Technology; 1:1000), FIP200

(14) Regulation of N-degron recognin-mediated autophagy by the SARS-CoV-2 PLpro ubiquitin deconjugaseAutophagyMay 1, 2025Ayala-Torres C, Liu J, Dantuma NP, Masucci MG.Millipore, 05–1307; 1:1000); anti-ATG9A (Abcam, ab108338; WB:1:1000); anti-ATG12 (Cell Signaling Technology, 4180S; 1:1000). Rabbit polyclonal: anti-FLAG (Sigma-Aldrich, F7425; IF: 1:400); anti-PLpro SARS-CoV-2 (GeneTex,

(15) The African swine fever virus gene MGF_360-4L inhibits interferon signaling by recruiting mitochondrial selective autophagy receptor SQSTM1 degrading MDA5 antagonizing innate immune responsesmBioApril 9, 2025Sun H, Yang J, Zhang Z, Wu M, Tian Z, Liu Y, Zhang X, Zhong J, Yang S, Chen Y, et al.(CST, 44060), rabbit anti-ATG5 (CST, 12994), rabbit anti-ATG7 (CST, 8558), rabbit anti-ATG12 (CST, 4180), and rabbit anti-ATG16L1 (CST, 8089) antibodies. Mouse anti-HSP60 (Proteintech, 2F1E7), rabbit anti-TOM20

(16) Acinetobacter baumannii OmpA hinders host autophagy via the CaMKK2-reliant AMPK-pathwaymBioApril 9, 2025Kyungho Woo, Dong Ho Kim, Ho-Sung Park, Man Hwan Oh, Je Chul Lee, Chul Hee Choi(Cell Signaling Technology, 8089), rabbit anti-p-ATG16L1 (Abcam, ab195242), rabbit anti-ATG12 (Cell Signaling Technology, 4180), rabbit anti-p-Beclin-1 (Cell Signaling Technology, 84966), rabbit anti-caspase 3 (Cell Signaling Technology,

(17) Scutellarin ameliorates ischemia/reperfusion-mediated endothelial dysfunction by upregulating cathepsin D expression to rescue autophagy-lysosomal functionFront PharmacolMarch 3, 2025Qizhen Zhuang, Lu Chen, Wanqian Wu, Qing Wang, Chunmin Kang, Yujuan Xiong, Xianzhang Huang(LC3)(3868s; CST), autophagy-related protein 5 (Atg5)(12994s; CST), autophagy-related protein 12 (Atg12)(4180s; CST), Beclin-1 (3495s; CST), P62 (39749s; CST), CTSD (A19680; Abclonal), LAMP1 (9091s; CST), ubiquitin

(18) Targeting NLRC5 in cardiomyocytes protects postinfarction cardiac injury by enhancing autophagy flux through the CAVIN1/CAV1 axisCommun BiolFebruary 23, 2025Lingfeng Gu, Sibo Wang, Liuhua Zhou, Wenjing Wang, Yulin Bao, Ye He, Tongtong Yang, Jiateng Sun, Qiqi Jiang, Tiankai Shan, et al.antibodies. The following primary antibodies were used: NLRC5 (ab105411) from Abcam, CAV1 (3267S), Atg12 (4180T), Atg5 (12994T), p70S6K (2708T), p-p70S6K (9234T), AMPKα (5831T), p-AMPKα (2535T), β-actin (4970S) from

(19) Hypoxia promotes tumor immune evasion by suppressing MHC-I expression and antigen presentationThe EMBO JournalJanuary 3, 2025Hala Estephan, Arun Tailor, Robert Parker, McKenzie Kreamer, Ioanna Papandreou, Leticia Campo, Alistair Easton, Eui Jung Moon, Nicholas C Denko, Nicola Ternette, et al.I)",Abcam,ab70328 LMP2,Abcam,ab3328 β-tubulin,Abcam,ab6046 p62,Cell Signaling,88588 LC3B,Cell Signaling,3868 ATG5,Cell Signaling,2630 ATG12,Cell Signaling,4180 ATF4,Cell Signaling,11815 IREα,Cell Signaling,3294 PERK,Cell Signaling,3192 LMP7,Cell Signaling,13635 NBR1,Santa Cruz

(20) Transcriptome profiling of DPP stimulated DPSCs identifies the role of autophagy in odontogenic differentiationJournal of Structural BiologyDecember 1, 2024Yinghua Chen, Cassandra Villani, Amudha Ganapathy, Anne Georgenonfat milk and probed with primary antibodies (Beclin-1(#3495), LC3A/B(#12741), Atg5 (#12994), Atg12 (#4180), Atg16L1 (#8089), Atg7 (#8558), Atg3 (#3415): all from Cell signaling.) overnight at 4 °C. They were

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Atg12 (D88H11) Rabbit mAb

Atg12 (D88H11) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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Atg12 (D88H11) Rabbit mAb from Cell Signaling Technology

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