RAD21 (D213) Antibody 4321S from Cell Signaling Technology

Product Specs
ItemRAD21 (D213) Antibody
CompanyCell Signaling Technology
Price $306.00 Inquire
Catalog Number4321S
Quantity100 µl
ApplicationsW, IP, IF-IC
ReactivityH, M, R, Mk
TargetRAD21
HostRabbit
NCBI Gene AliasesCDLS4, HR21, HRAD21, MCD1, MGS, NXP1, SCC1, hHR21
NCBI Full Gene NameRAD21 cohesin complex component
ClonalityPolyclonal
Research AreaCell Cycle / Checkpoint Control
CloneD213
Molecular Weight130

Add to Compare List

Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) CTCF maintains centromere function and mitotic fidelityJournal of Cell ScienceFebruary 1, 2026Erin Walsh, Thomas Laskarzewski, Thomas J. Maresca, Andrew D. Stephensrabbit anti-CTCF antibody (Cell Signaling, 2899) at 1:2500, rabbit anti-RAD21 antibody (Cell Signaling, 4321) at 1:2500, mouse anti-α-tubulin antibody (Sigma-Aldrich, T9026) at 1:5000, and mouse anti-Lamin A/C

(2) The METTL3-YTHDC1 axis mediates architectural RNA m6A modification to modulate the integrity of chromatin TADs in MLLr + AML genomeMolecular CancerDecember 22, 2025Ruishuang Fu, Wenjuan Yu, Rongjie Zhao, Huimin Yang, Beibei Cao, Chunfei Dai, Haoyue Qianjiang, Yujun Xia, Lubo Wang, Jianrong Lu, et al.Technology, Cat# 2622; anti-METTL3, Abcam Cat# ab195352; Anti-RAD21, Cell Signaling Technology, Cat# 4321; Anti-YTHDC1, Abcam, Cat#ab122340; Anti-MLL, Thermo Fisher Scientific, Cat#A300-086 A; Anti-AF9 antibody,

(3) Lentivirus Enables the Detection of Strand-Specific ssDNA Gaps by the DNA Fiber Spreading AssayResearch SquareDecember 12, 2025Melisande shao, Melisande Wong, Evan Brown Ton, Evan Brown Shaoin PBS, followed by overnight incubation with primary antibodies for Rad21 (1:200, Cell Signaling, #4321) and Biotin (1:1000, Jackson ImmunoResearch, 200-002-211) at 4°C. On the following day, cells were subjected

(4) Cirsiliol alleviates diabetic cardiomyopathy by inhibiting oxidative stress and improving energy metabolism through the PPAR-α/AMPK pathwayScientific ReportsDecember 11, 2025Jing Tao, Siqi Liu, Yunzhi Ling, Hanlin Bai, Lei Liu, Ru Yu, Guangling Li2029), PPAR-α (Catalog # 2435), AMPK (Catalog # 5831), LKB1 (Catalog # 3047), and ACADM (Catalog # 4321) were purchased from Cell Signaling Technology. The antibody for IL-8 (Catalog # ab289967) was purchased

(5) Systematic comparison and base-editing-mediated directed protein evolution and functional screening yield superior auxin-inducible degron technologyNat CommunJuly 18, 2025De Xing, Tao Bai, Ozlem Neyisci, Seyedeh Zahra Paylakhi, Alexander J. Duval, Yasemin Tekin, Mazhar Adliantibodies (1:1000 dilution) overnight at 4 °C. Primary antibodies including RAD21 (Cell Signaling, 4321S), CTCF (Cell Signaling, 2899S), DNMT3B (Cell Signaling, 67259), RBAP46/RBAP48 (Cell Signaling, 9067),

(6) CTCF/RAD21 organize the ground state of chromatin–nuclear speckle associationNature Structural & Molecular BiologyJune 1, 2025Ruofan Yu, Shelby Roseman, Allison P. Siegenfeld, Zachary Gardner, Son C. Nguyen, Khoa A. Tran, Eric F. Joyce, Rajan Jain, Brian B. Liau, Ian D. Krantz, et al.4 °C: anti-CTCF antibody (1:5,000, Abcam, ab188408), anti-RAD21 antibody (1:1,000, Cell Signaling, 4321s), anti-GAPDH antibody (1:1,000, Cell Signaling, 5174), anti-H3 antibody (1:2,500, Abcam, ab1791), anti-STAG1

(7) NIPBL-mediated RAD21 facilitates tumorigenicity by the PI3K pathway in non-small-cell lung cancerCommunications BiologyFebruary 20, 2024Xiaoling Xu, Ding Wang, Weizhen Xu, Huihui Li, Ning Chen, Na Li, Qifeng Yao, Jianxiang Zhong, Wei Chen, Weimin Maochromatin samples were then incubated with 1 μg of NIPBL antibody (#ab245539, Abcam), RAD21 antibody (#4321, Cell Signaling Technology, Danvers, MA, USA), H3K27me3 antibody (#21800-1-AP, Proteintech, Rosemont,

(8) STAG2 Regulates Homologous Recombination Repair and Sensitivity to ATM InhibitionAdvanced ScienceNovember 20, 2023Jie Zhou, Run‐Cong Nie, Zhang‐Ping He, Xiao‐Xia Cai, Jie‐Wei Chen, Wen‐ping Lin, Yi‐Xin Yin, Zhi‐Cheng Xiang, Tian‐Chen Zhu, Juan‐Juan Xie, et al.1:10 000), 53BP1 (CST 4937S, IF, 1:200; IB, 1:1000), RPA32 (CST 2208S, IF, 1:200; IB, 1:1000), RAD21 (CST 4321S, IB,1:1000), H4 (Abcam ab177188, IB, 1:1000), H4K20me0 (Abcam ab227804, IB, 1:1000; IHC, 1:100), H4K20me1

(9) Integrative Multi-OMICs Identifies Therapeutic Response Biomarkers and Confirms Fidelity of Clinically Annotated, Serially Passaged Patient-Derived Xenografts Established from Primary and Metastatic Pediatric and AYA Solid TumorsCancersDecember 30, 2022Pandya PH, Jannu AJ, Bijangi-Vishehsaraei K, Dobrota E, Bailey BJ, Barghi F, Shannon HE, Riyahi N, Damayanti NP, Young C, et al.BSA in TBS-T per manufacturer’s instruction and used for detection: rabbit anti-RAD21 (130 kDa, cat# 4321, Cell Signaling Technology, Boston, MA, USA); mouse anti-c-MYC [9E10] (67 kDa, cat# sc-40, Santa Cruz Biotechnology, Inc

(10) Impaired Cdc20 signaling promotes senescence in normal cells and apoptosis in non-small cell lung cancer cellsThe Journal of biological chemistryOctober 1, 2022Volonte D, Sedorovitz M, Galbiati F.(14866), anti-securin (13445), anti-phospho-p53 (9284), anti-γ-H2A.X (9718), Apc2 (12301), and anti-Rad21 (4321) IgGs were from Cell Signaling Technologies; anti-β-actin (mAb C4), anti-p21 (F-5), anti-p53 (6243);

(11) Genetic analysis of cancer drivers reveals cohesin and CTCF as suppressors of PD-L1Proceedings of the National Academy of Sciences of the United States of AmericaFebruary 15, 2022Oreskovic E, Wheeler EC, Mengwasser KE, Fujimura E, Martin TD, Tothova Z, Elledge SJ.catalog no. V9131) from Sigma, STAG1 (catalog no. 14015-1-AP) from Proteintech and RAD21 (catalog no. 4321), CTCF (catalog no. 2899S), STAG2 (catalog no. 4239), PD-L1 (catalog no. 29122), p-p65 (catalog no.

(12) The deacetylation-phosphorylation regulation of SIRT2-SMC1A axis as a mechanism of antimitotic catastrophe in early tumorigenesisScience advancesFebruary 1, 2021Yi F, Zhang Y, Wang Z, Wang Z, Li Z, Zhou T, Xu H, Liu J, Jiang B, Li X, et al.pSer10 H3-P (#3377, CST), α-tubulin (AT819, Beyotime), CBP (#7389, CST), HA-Tag (#3724S, CST), RAD21 (#4321, CST), Rae1 (ab124783, Abcam), cleaved PARP (#5625, CST), cleaved caspase-3 (#25546-1-AP, Proteintech),

(13) Systems Biology Approach Identifies Prognostic Signatures of Poor Overall Survival and Guides the Prioritization of Novel BET-CHK1 Combination Therapy for OsteosarcomaCancersAugust 26, 2020Pandya PH, Cheng L, Saadatzadeh MR, Bijangi-Vishehsaraei K, Tang S, Sinn AL, Trowbridge MA, Coy KL, Bailey BJ, Young CN, et al.anti-BRD4 [E2A7X] (200 kDa, cat# 13440, Cell Signaling Technology); rabbit anti-RAD21 (130 kDa, cat# 4321, Cell Signaling Technology); rabbit anti-phospho-H2A.X serine 139 [p-H2AX-Ser139] (15 kDa, cat# 2577,

(14) Regulation of sister chromatid cohesion by nuclear PD-L1Cell researchJuly 1, 2020Yu J, Qin B, Moyer AM, Nowsheen S, Tu X, Dong H, Boughey JC, Goetz MP, Weinshilboum R, Lou Z, et al.purchased from Origene. Anti-SMC1 antibody (4802S), anti-SMC3 antibody (5696S), anti-SCC1 antibody (4321S), anti-STAG2 antibody (5882S), anti-WAPL antibody (77428S) and anti-PD-L1 antibody (13684S, for Western blot

(15) Topologically Associated Domains Delineate Susceptibility to Somatic HypermutationCell reportsDecember 17, 2019Senigl F, Maman Y, Dinesh RK, Alinikula J, Seth RB, Pecnova L, Omer AD, Rao SSP, Weisz D, Buerstedde JM, et al.#PA5-52247), p65 (CST #8242), c-Rel (CST #12659), Nuclear Pore Proteins (Abcam #ab24609), Rad21 (CST #4321), Pax5 (Novus #NBP2-29905), YY2 (Sigma #HPA030335. ChIP-seq data for NIPBL, H3K4me1 and H3K4me3 were

(16) Superresolution microscopy reveals linkages between ribosomal DNA on heterologous chromosomesThe Journal of cell biologyAugust 5, 2019Potapova TA, Unruh JR, Yu Z, Rancati G, Li H, Stampfer MR, Gerton JL.(ab70493; Abcam), GAPDH (D16H11) rabbit mAb (5174; Cell Signaling Technology), RAD21 (D213) antibody (4321; Cell Signaling Technology), β-Actin (8H10D10) mouse mAb (3700; Cell Signaling Technology), Ki-67 (8D5) mouse mAb

(17) Interaction of the Warsaw breakage syndrome DNA helicase DDX11 with the replication fork-protection factor Timeless promotes sister chromatid cohesionPLoS geneticsOctober 1, 2018Cortone G, Zheng G, Pensieri P, Chiappetta V, Tatè R, Malacaria E, Pichierri P, Yu H, Pisani FM.A300-060A); GAPDH (Cell Signalling, 2118S); Smc1 (Abcam, ab117610); Scc1 (Cell Signaling Technology, 4321S); Mcm4 (Abcam, ab4459); Cdc45 (a rat monoclonal antibody donated by Hans-Peter Nasheuer, Galway, Ireland;

(18) Diet-Induced Circadian Enhancer Remodeling Synchronizes Opposing Hepatic Lipid Metabolic ProcessesCellAugust 9, 2018Guan D, Xiong Y, Borck PC, Jang C, Doulias PT, Papazyan R, Fang B, Jiang C, Zhang Y, Briggs ER, et al.,Santa Cruz Biotechnology,Cat# sc-398394 SREBP1c,Abcam,"Cat# ab3259, RRID:AB_303650" RAD21,Cell Signaling Technology,"Cat# 4321S, RRID:AB_1904106" Chemicals and Reagents,Chemicals and Reagents,Chemicals and Reagents TRIzol,ThermoFisher Scientific

(19) Three-Dimensional Cell Culture Conditions Affect the Proteome of Cancer-Associated FibroblastsJournal of proteome researchAugust 3, 2018Tölle RC, Gaggioli C, Dengjel J.Midwood, K. S.; Chiquet, M.; Tucker, R. P.; Orend, G. Tenascin-C at a glance. J. Cell Sci. 2016, 129 (23), 4321−7. (50) Ishii, K.; Mizokami, A.; Tsunoda, T.; Iguchi, K.; Kato, M.; Hori, Y.; Arima, K.; Namiki, M.;

(20) The hepatic circadian clock fine-tunes the lipogenic response to feeding through RORα/γGenes & DevelopmentJune 15, 2017Yuxiang Zhang, Romeo Papazyan, Manashree Damle, Bin Fang, Jennifer Jager, Dan Feng, Lindsey C. Peed, Dongyin Guan, Zheng Sun, Mitchell A. Lazar(sc-28612), anti-RORγ antibody from Abcam (ab78007), and anti-Rad21 antibody from Cell Signaling Technology (4321S). Gene expression analysis Total RNA was extracted from liver tissue using Trizol reagent (Life Techologies)

Be the First to Write a Review!

RAD21 (D213) Antibody

RAD21 (D213) Antibody from Cell Signaling Technology

Description

Cell Signaling Technology

Citations (30)

Reviews

RAD21 (D213) Antibody from Cell Signaling Technology

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map