M-CSF R/CD115 Antibody MAB3291-100 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemM-CSF R/CD115 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $499.00Supplier Page View Company Product Page
Catalog NumberMAB3291-100
Quantity100 ug (also 25 ug, 500 ug)
ApplicationsBioassay,Immunohistochemistry,Immunoprecipitation,Western Blot,Neutralization,Immunocytochemistry,Functional Assay
Conjugate/TagUnconjugated
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ReactivityHuman,Mouse
TargetM-CSF R/CD115
IsotypeIgG1
Clone61701
HostMouse
ImmunogenMouse myeloma cell line NS0-derived recombinant human M-CSF R/CD115, Ile20-Glu512 (Pro54Ala), Accession # P07333.2
NCBI Full Gene Namecolony stimulating factor 1 receptor
NCBI Gene AliasesFIM2, HDLS1, CD115, M-CSF-R, FMS, CSFR, C-FMS, GPSC, BANDDOS, CSF-1R, HDLS
ClonalityMonoclonal
PurityProtein A or G purified from hybridoma culture supernatant
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects human M-CSF R/CD115 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) GM-CSF R alpha or rhGM-CSF Rß is observed.

Sizes Available: 100 ug (also 25 ug, 500 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) An adapted protocol to derive microglia from stem cells and its application in the study of CSF1R-related disordersMolecular neurodegenerationApril 5, 2024Dorion MF, Casas D, Shlaifer I, Yaqubi M, Fleming P, Karpilovsky N, Chen CX, Nicouleau M, Piscopo VEC, MacDougall EJ, et al.

(2) Extracellular vesicles from triple negative breast cancer promote pro-inflammatory macrophages associated with better clinical outcomeProceedings of the National Academy of Sciences of the United States of AmericaApril 26, 2022Tkach M, Thalmensi J, Timperi E, Gueguen P, Névo N, Grisard E, Sirven P, Cocozza F, Gouronnec A, Martin-Jaular L, et al.

(3) Age-related changes in brain phospholipids and bioactive lipids in the APP knock-in mouse model of Alzheimer's diseaseActa neuropathologica communicationsJune 29, 2021Emre C, Do KV, Jun B, Hjorth E, Alcalde SG, Kautzmann MI, Gordon WC, Nilsson P, Bazan NG, Schultzberg M.

(4) Osteopontin Links Myeloid Activation and Disease Progression in Systemic SclerosisCell reports. MedicineNovember 17, 2020Gao X, Jia G, Guttman A, DePianto DJ, Morshead KB, Sun KH, Ramamoorthi N, Vander Heiden JA, Modrusan Z, Wolters PJ, et al.

(5) Phenotype of vigilin expressing breast cancer cells binding to the 69 nt 3'UTR element in CSF-1R mRNATranslational oncologyJanuary 1, 2019Woo HH, Lee SC, Stoffer JB, Rush D, Chambers SK.

(6) IL-34 Upregulated Th17 Production through Increased IL-6 Expression by Rheumatoid Fibroblast-Like SynoviocytesMediators of inflammationJanuary 1, 2017Wang B, Ma Z, Wang M, Sun X, Tang Y, Li M, Zhang Y, Li F, Li X.

(7) Receptor-Type Protein-Tyrosine Phosphatase ζ and Colony Stimulating Factor-1 Receptor in the Intestine: Cellular Expression and Cytokine- and Chemokine Responses by Interleukin-34 and Colony Stimulating Factor-1PloS oneJanuary 1, 2016Zwicker S, Bureik D, Bosma M, Martinez GL, Almer S, Boström EA.

(8) Autocrine CSF1R signaling mediates switching between invasion and proliferation downstream of TGFβ in claudin-low breast tumor cellsOncogeneMay 21, 2015Patsialou A, Wang Y, Pignatelli J, Chen X, Entenberg D, Oktay M, Condeelis JS.

(9) Invasive breast carcinoma cells from patients exhibit MenaINV- and macrophage-dependent transendothelial migrationScience signalingNovember 25, 2014Pignatelli J, Goswami S, Jones JG, Rohan TE, Pieri E, Chen X, Adler E, Cox D, Maleki S, Bresnick A, et al.

(10) Macrophage colony-stimulating factor augments Tie2-expressing monocyte differentiation, angiogenic function, and recruitment in a mouse model of breast cancerPloS oneJanuary 1, 2014Forget MA, Voorhees JL, Cole SL, Dakhlallah D, Patterson IL, Gross AC, Moldovan L, Mo X, Evans R, Marsh CB, et al.

(11) Derepression of an endogenous long terminal repeat activates the CSF1R proto-oncogene in human lymphomaNature medicineMay 1, 2010Lamprecht B, Walter K, Kreher S, Kumar R, Hummel M, Lenze D, Köchert K, Bouhlel MA, Richter J, Soler E, et al.

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M-CSF R/CD115 Antibody

M-CSF R/CD115 Antibody

M-CSF R/CD115 Antibody

M-CSF R/CD115 Antibody

M-CSF R/CD115 Antibody

M-CSF R/CD115 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (11)

Reviews

M-CSF R/CD115 Antibody from R&D Systems, a Bio-Techne Brand

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